|
1 | Locus | Length | Locus description |
![Ortho button](graphics/orthoButton.png) |
961 | YDR072C | 527 | YDR072C IPT1 SGDID:S000002479, Chr IV from 591344-589761, Genome Release 64-1-1, reverse complement, Verified ORF, "Inositolphosphotransferase, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), the most abundant sphingolipid;, can mutate to resistance to the antifungals syringomycin E and DmAMP1 and to K. lactis zymocin" |
![Ortho button](graphics/orthoButton.png) |
962 | YDR073W | 169 | YDR073W SNF11 SGDID:S000002480, Chr IV from 592439-592948, Genome Release 64-1-1, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p" |
![Ortho button](graphics/orthoButton.png) |
963 | YDR074W | 896 | YDR074W TPS2 SGDID:S000002481, Chr IV from 593893-596583, Genome Release 64-1-1, Verified ORF, "Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway" |
![Ortho button](graphics/orthoButton.png) |
964 | YDR075W | 308 | YDR075W PPH3 SGDID:S000002482, Chr IV from 597156-598082, Genome Release 64-1-1, Verified ORF, "Catalytic subunit of protein phosphatase PP4 complex; active complex is composed of Pph3p and Psy2p, with Psy4p apparently providing additional substrate specificity in some cases; regulates recovery from the DNA damage checkpoint and also the gene conversion- and single-strand annealing-mediated pathways of meiotic double-strand break repair; involved in activation of Gln3p to alleviate nitrogen catabolite repression; Pph3p and Psy2p localize to foci on meiotic chromosomes" |
![Ortho button](graphics/orthoButton.png) |
965 | YDR076W | 406 | YDR076W RAD55 SGDID:S000002483, Chr IV from 598468-599688, Genome Release 64-1-1, Verified ORF, "Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p" |
![Ortho button](graphics/orthoButton.png) |
966 | YDR077W | 338 | YDR077W SED1 SGDID:S000002484, Chr IV from 600793-601809, Genome Release 64-1-1, Verified ORF, "Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites" |
![Ortho button](graphics/orthoButton.png) |
967 | YDR078C | 223 | YDR078C SHU2 SGDID:S000002485, Chr IV from 602869-602198, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu1p, Psy3p, and Csm2p" |
![Ortho button](graphics/orthoButton.png) |
968 | YDR079C-A | 72 | YDR079C-A TFB5 SGDID:S000007603, Chr IV from 603811-603593, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair" |
![Ortho button](graphics/orthoButton.png) |
969 | YDR079W | 111 | YDR079W PET100 SGDID:S000002486, Chr IV from 603064-603399, Genome Release 64-1-1, Verified ORF, "Chaperone that specifically facilitates the assembly of cytochrome c oxidase, integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme" |
![Ortho button](graphics/orthoButton.png) |
970 | YDR080W | 992 | YDR080W VPS41 SGDID:S000002487, Chr IV from 604008-606986, Genome Release 64-1-1, Verified ORF, "Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport" |
![Ortho button](graphics/orthoButton.png) |
971 | YDR081C | 925 | YDR081C PDC2 SGDID:S000002488, Chr IV from 610081-607304, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes" |
![Ortho button](graphics/orthoButton.png) |
972 | YDR082W | 494 | YDR082W STN1 SGDID:S000002489, Chr IV from 610441-611925, Genome Release 64-1-1, Verified ORF, "Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping" |
![Ortho button](graphics/orthoButton.png) |
973 | YDR083W | 392 | YDR083W RRP8 SGDID:S000002490, Chr IV from 612073-613251, Genome Release 64-1-1, Verified ORF, "Nucleolar protein involved in rRNA processing, pre-rRNA cleavage at site A2; also involved in telomere maintenance; mutation is synthetically lethal with a gar1 mutation" |
![Ortho button](graphics/orthoButton.png) |
974 | YDR084C | 199 | YDR084C TVP23 SGDID:S000002491, Chr IV from 614004-613405, Genome Release 64-1-1, reverse complement, Verified ORF, "Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
![Ortho button](graphics/orthoButton.png) |
975 | YDR085C | 620 | YDR085C AFR1 SGDID:S000002492, Chr IV from 616150-614288, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for pheromone-induced projection (shmoo) formation; regulates septin architecture during mating; has an RVXF motif that mediates targeting of Glc7p to mating projections; interacts with Cdc12p" |
![Ortho button](graphics/orthoButton.png) |
976 | YDR086C | 80 | YDR086C SSS1 SGDID:S000002493, Chr IV from 617170-616928, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p" |
![Ortho button](graphics/orthoButton.png) |
977 | YDR087C | 278 | YDR087C RRP1 SGDID:S000002494, Chr IV from 618306-617470, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential evolutionarily conserved nucleolar protein necessary for biogenesis of 60S ribosomal subunits and processing of pre-rRNAs to mature rRNAs, associated with several distinct 66S pre-ribosomal particles" |
![Ortho button](graphics/orthoButton.png) |
978 | YDR088C | 382 | YDR088C SLU7 SGDID:S000002495, Chr IV from 619645-618497, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA splicing factor, required for ATP-independent portion of 2nd catalytic step of spliceosomal RNA splicing; interacts with Prp18p; contains zinc knuckle domain" |
![Ortho button](graphics/orthoButton.png) |
979 | YDR089W | 869 | YDR089W YDR089W SGDID:S000002496, Chr IV from 622112-624721, Genome Release 64-1-1, Uncharacterized ORF, "Protein of unknown function; deletion confers resistance to Nickel" |
![Ortho button](graphics/orthoButton.png) |
980 | YDR090C | 310 | YDR090C YDR090C SGDID:S000002497, Chr IV from 625998-625066, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
![Ortho button](graphics/orthoButton.png) |
981 | YDR091C | 608 | YDR091C RLI1 SGDID:S000002498, Chr IV from 628534-626708, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential iron-sulfur protein required for ribosome biogenesis and translation initiation and termination; facilitates binding of a multifactor complex (MFC) of initiation factors to the small ribosomal subunit; predicted ABC family ATPase" |
![Ortho button](graphics/orthoButton.png) |
982 | YDR092W | 153 | YDR092W UBC13 SGDID:S000002499, Chr IV from 629876-629905,630174-630605, Genome Release 64-1-1, Verified ORF, "Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus" |
![Ortho button](graphics/orthoButton.png) |
983 | YDR093W | 1612 | YDR093W DNF2 SGDID:S000002500, Chr IV from 631282-636120, Genome Release 64-1-1, Verified ORF, "Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase" |
![Ortho button](graphics/orthoButton.png) |
984 | YDR096W | 894 | YDR096W GIS1 SGDID:S000002503, Chr IV from 637139-639823, Genome Release 64-1-1, Verified ORF, "JmjC domain-containing histone demethylase and transcription factor; involved in expression of genes during nutrient limitation; negatively regulates DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis; has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity; contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain" |
![Ortho button](graphics/orthoButton.png) |
985 | YDR097C | 1242 | YDR097C MSH6 SGDID:S000002504, Chr IV from 643837-640109, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p" |
![Ortho button](graphics/orthoButton.png) |
986 | YDR098C | 285 | YDR098C GRX3 SGDID:S000002505, Chr IV from 645035-644178, Genome Release 64-1-1, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage" |
![Ortho button](graphics/orthoButton.png) |
987 | YDR098C-A | 440 | YDR098C-A YDR098C-A SGDID:S000007390, Chr IV from 651126-649804, Genome Release 64-1-1, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
![Ortho button](graphics/orthoButton.png) |
988 | YDR098C-B | 1755 | YDR098C-B YDR098C-B SGDID:S000007391, Chr IV from 649820-645858,651126-649822, Genome Release 64-1-1, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
![Ortho button](graphics/orthoButton.png) |
989 | YDR099W | 273 | YDR099W BMH2 SGDID:S000002506, Chr IV from 653607-654428, Genome Release 64-1-1, Verified ORF, "14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling" |
![Ortho button](graphics/orthoButton.png) |
990 | YDR100W | 143 | YDR100W TVP15 SGDID:S000002507, Chr IV from 655013-655444, Genome Release 64-1-1, Verified ORF, "Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p" |