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1 | Locus | Length | Locus description |
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781 | YDL131W | 440 | YDL131W LYS21 SGDID:S000002289, Chr IV from 227393-228715, Genome Release 64-1-1, Verified ORF, "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys20p" |
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782 | YDL132W | 815 | YDL132W CDC53 SGDID:S000002290, Chr IV from 224304-226751, Genome Release 64-1-1, Verified ORF, "Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation" |
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783 | YDL133C-A | 25 | YDL133C-A RPL41B SGDID:S000002293, Chr IV from 221801-221724, Genome Release 64-1-1, reverse complement, Verified ORF, "Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Ap and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable" |
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784 | YDL133W | 437 | YDL133W SRF1 SGDID:S000002291, Chr IV from 222427-223740, Genome Release 64-1-1, Verified ORF, "Regulator of phospholipase D (Spo14p); interacts with Spo14p and regulates its catalytic activity; capable of buffering the toxicity of C16:0 platelet activating factor, a lipid that accumulates intraneuronally in Alzheimer's patients" |
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785 | YDL134C | 369 | YDL134C PPH21 SGDID:S000002292, Chr IV from 220771-219662, Genome Release 64-1-1, reverse complement, Verified ORF, "Catalytic subunit of protein phosphatase 2A (PP2A), functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis" |
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786 | YDL135C | 202 | YDL135C RDI1 SGDID:S000002294, Chr IV from 219288-218680, Genome Release 64-1-1, reverse complement, Verified ORF, "Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p and Rho1p" |
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787 | YDL136W | 120 | YDL136W RPL35B SGDID:S000002295, Chr IV from 217600-217602,218008-218367, Genome Release 64-1-1, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein" |
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788 | YDL137W | 181 | YDL137W ARF2 SGDID:S000002296, Chr IV from 216529-217074, Genome Release 64-1-1, Verified ORF, "ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p" |
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789 | YDL138W | 763 | YDL138W RGT2 SGDID:S000002297, Chr IV from 213351-215642, Genome Release 64-1-1, Verified ORF, "Plasma membrane high glucose sensor that regulates glucose transport; contains 12 predicted transmembrane segments and a long C-terminal tail required for induction of hexose transporters; highly similar to Snf3p" |
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790 | YDL139C | 223 | YDL139C SCM3 SGDID:S000002298, Chr IV from 212046-211375, Genome Release 64-1-1, reverse complement, Verified ORF, "Nonhistone component of centromeric chromatin that binds stoichiometrically to CenH3-H4 histones, required for kinetochore assembly; required for G2/M progression and localization of Cse4p; may protect Cse4p from ubiquitylation" |
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791 | YDL140C | 1733 | YDL140C RPO21 SGDID:S000002299, Chr IV from 210561-205360, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime" |
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792 | YDL141W | 690 | YDL141W BPL1 SGDID:S000002300, Chr IV from 203039-205111, Genome Release 64-1-1, Verified ORF, "Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation" |
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793 | YDL142C | 283 | YDL142C CRD1 SGDID:S000002301, Chr IV from 202570-201719, Genome Release 64-1-1, reverse complement, Verified ORF, "Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis" |
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794 | YDL143W | 528 | YDL143W CCT4 SGDID:S000002302, Chr IV from 199996-201582, Genome Release 64-1-1, Verified ORF, "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" |
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795 | YDL144C | 356 | YDL144C YDL144C SGDID:S000002303, Chr IV from 199732-198662, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL144C is not an essential gene." |
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796 | YDL145C | 1201 | YDL145C COP1 SGDID:S000002304, Chr IV from 198176-194571, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway" |
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797 | YDL146W | 491 | YDL146W LDB17 SGDID:S000002305, Chr IV from 192750-194225, Genome Release 64-1-1, Verified ORF, "Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck" |
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798 | YDL147W | 445 | YDL147W RPN5 SGDID:S000002306, Chr IV from 190924-192261, Genome Release 64-1-1, Verified ORF, "Subunit of the COP9 signalosome (CSN) and non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p; Rpn5p is an essential protein" |
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799 | YDL148C | 810 | YDL148C NOP14 SGDID:S000002307, Chr IV from 190586-188154, Genome Release 64-1-1, reverse complement, Verified ORF, "Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA" |
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800 | YDL149W | 997 | YDL149W ATG9 SGDID:S000002308, Chr IV from 184925-187918, Genome Release 64-1-1, Verified ORF, "Transmembrane protein involved in forming Cvt and autophagic vesicles; cycles between the phagophore assembly site (PAS) and other cytosolic punctate structures, not found in autophagosomes; may be involved in membrane delivery to the PAS" |
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801 | YDL150W | 422 | YDL150W RPC53 SGDID:S000002309, Chr IV from 183343-184611, Genome Release 64-1-1, Verified ORF, "RNA polymerase III subunit C53" |
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802 | YDL153C | 610 | YDL153C SAS10 SGDID:S000002312, Chr IV from 183018-181186, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit; disrupts silencing when overproduced; mutant has increased aneuploidy tolerance" |
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803 | YDL154W | 901 | YDL154W MSH5 SGDID:S000002313, Chr IV from 178334-181039, Genome Release 64-1-1, Verified ORF, "Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans" |
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804 | YDL155W | 427 | YDL155W CLB3 SGDID:S000002314, Chr IV from 176773-178056, Genome Release 64-1-1, Verified ORF, "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation" |
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805 | YDL156W | 522 | YDL156W YDL156W SGDID:S000002315, Chr IV from 174918-176486, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; potential regulatory target of Mbp1p, which binds to the YDL156W promoter region" |
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806 | YDL157C | 118 | YDL157C YDL157C SGDID:S000002316, Chr IV from 174588-174232, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
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807 | YDL159W | 515 | YDL159W STE7 SGDID:S000002318, Chr IV from 172481-174028, Genome Release 64-1-1, Verified ORF, "Signal transducing MAP kinase kinase involved in pheromone response, where it phosphorylates Fus3p, and in the pseudohyphal/invasive growth pathway, through phosphorylation of Kss1p; phosphorylated by Ste11p, degraded by ubiquitin pathway" |
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808 | YDL159W-A | 43 | YDL159W-A YDL159W-A SGDID:S000007599, Chr IV from 172182-172313, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species" |
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809 | YDL160C | 506 | YDL160C DHH1 SGDID:S000002319, Chr IV from 171930-170410, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation" |
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810 | YDL160C-A | 80 | YDL160C-A YDL160C-A SGDID:S000028520, Chr IV from 169608-169366, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; mutant in a srs2 mutant background displays MMS hypersensitivity; ortholog of human MHF2, a component of the Fanconi anemia (FA) complex that is involved in maintaining genome stability" |