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1 | Locus | Length | Locus description |
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661 | YCR108C | 63 | YCR108C YCR108C SGDID:S000028536, Chr III from 316188-315997, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
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662 | YDL001W | 430 | YDL001W RMD1 SGDID:S000002159, Chr IV from 447984-449276, Genome Release 64-1-1, Verified ORF, "Cytoplasmic protein required for sporulation" |
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663 | YDL002C | 203 | YDL002C NHP10 SGDID:S000002160, Chr IV from 447578-446967, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein related to mammalian high mobility group proteins; preferentially binds DNA ends, protecting them from exonucleatic cleavage; likely component of the chromatin-remodeling complex INO80 complex; proposed to be involved in DNA repair" |
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664 | YDL003W | 566 | YDL003W MCD1 SGDID:S000002161, Chr IV from 444683-446383, Genome Release 64-1-1, Verified ORF, "Essential subunit of the cohesin complex required for sister chromatid cohesion in mitosis and meiosis; apoptosis induces cleavage and translocation of a C-terminal fragment to mitochondria; expression peaks in S phase" |
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665 | YDL004W | 160 | YDL004W ATP16 SGDID:S000002162, Chr IV from 443029-443511, Genome Release 64-1-1, Verified ORF, "Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" |
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666 | YDL005C | 431 | YDL005C MED2 SGDID:S000002163, Chr IV from 442309-441014, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
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667 | YDL006W | 281 | YDL006W PTC1 SGDID:S000002164, Chr IV from 439909-440754, Genome Release 64-1-1, Verified ORF, "Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p, inactivating osmosensing MAPK cascade; involved in Fus3p activation during pheromone response; deletion affects precursor tRNA splicing, mitochondrial inheritance, and sporulation" |
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668 | YDL007C-A | 85 | YDL007C-A YDL007C-A SGDID:S000113557, Chr IV from 436824-436567, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
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669 | YDL007W | 437 | YDL007W RPT2 SGDID:S000002165, Chr IV from 438047-439360, Genome Release 64-1-1, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle" |
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670 | YDL008W | 165 | YDL008W APC11 SGDID:S000002166, Chr IV from 433497-433994, Genome Release 64-1-1, Verified ORF, "Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; contains a RING-H2 domain that is required for activity" |
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671 | YDL010W | 231 | YDL010W GRX6 SGDID:S000002168, Chr IV from 432330-433025, Genome Release 64-1-1, Verified ORF, "Cis-golgi localized monothiol glutaredoxin that binds an iron-sulfur cluster; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; functional overlap with GRX7" |
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672 | YDL012C | 107 | YDL012C YDL012C SGDID:S000002170, Chr IV from 431386-431108,431517-431473, Genome Release 64-1-1, reverse complement, Verified ORF, "Tail-anchored plasma membrane protein containing a conserved CYSTM module, possibly involved in response to stress; may contribute to non-homologous end-joining (NHEJ) based on ydl012c htz1 double null phenotype" |
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673 | YDL013W | 619 | YDL013W SLX5 SGDID:S000002171, Chr IV from 429067-430926, Genome Release 64-1-1, Verified ORF, "Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex, stimulated by SUMO-modified substrates; contains a RING domain and two SIMs (SUMO-interacting motifs); forms SUMO-dependent nuclear foci, including DNA repair centers" |
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674 | YDL014W | 327 | YDL014W NOP1 SGDID:S000002172, Chr IV from 427364-428347, Genome Release 64-1-1, Verified ORF, "Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin" |
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675 | YDL015C | 310 | YDL015C TSC13 SGDID:S000002173, Chr IV from 426934-426002, Genome Release 64-1-1, reverse complement, Verified ORF, "Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation, localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions, coimmunoprecipitates with elongases Fen1p and Sur4p" |
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676 | YDL017W | 507 | YDL017W CDC7 SGDID:S000002175, Chr IV from 424209-425732, Genome Release 64-1-1, Verified ORF, "DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression" |
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677 | YDL018C | 225 | YDL018C ERP3 SGDID:S000002176, Chr IV from 423510-422833, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" |
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678 | YDL019C | 1283 | YDL019C OSH2 SGDID:S000002177, Chr IV from 421514-417663, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" |
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679 | YDL020C | 531 | YDL020C RPN4 SGDID:S000002178, Chr IV from 416708-415113, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses" |
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680 | YDL021W | 311 | YDL021W GPM2 SGDID:S000002179, Chr IV from 413953-414888, Genome Release 64-1-1, Verified ORF, "Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event" |
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681 | YDL022W | 391 | YDL022W GPD1 SGDID:S000002180, Chr IV from 411825-413000, Genome Release 64-1-1, Verified ORF, "NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p" |
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682 | YDL024C | 468 | YDL024C DIA3 SGDID:S000002182, Chr IV from 409857-408451, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function, involved in invasive and pseudohyphal growth" |
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683 | YDL025C | 620 | YDL025C RTK1 SGDID:S000002183, Chr IV from 407206-405344, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1" |
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684 | YDL027C | 420 | YDL027C YDL027C SGDID:S000002185, Chr IV from 404957-403695, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene" |
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685 | YDL028C | 764 | YDL028C MPS1 SGDID:S000002186, Chr IV from 403291-400997, Genome Release 64-1-1, reverse complement, Verified ORF, "Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p" |
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686 | YDL029W | 391 | YDL029W ARP2 SGDID:S000002187, Chr IV from 399340-399361,399485-400638, Genome Release 64-1-1, Verified ORF, "Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity" |
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687 | YDL030W | 530 | YDL030W PRP9 SGDID:S000002188, Chr IV from 397537-399129, Genome Release 64-1-1, Verified ORF, "Subunit of the SF3a splicing factor complex, required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex" |
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688 | YDL031W | 995 | YDL031W DBP10 SGDID:S000002189, Chr IV from 394217-397204, Genome Release 64-1-1, Verified ORF, "Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis" |
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689 | YDL033C | 417 | YDL033C SLM3 SGDID:S000002191, Chr IV from 393912-392659, Genome Release 64-1-1, reverse complement, Verified ORF, "tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human ortholog is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF)" |
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690 | YDL035C | 961 | YDL035C GPR1 SGDID:S000002193, Chr IV from 392057-389172, Genome Release 64-1-1, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" |