|
1 | Locus | Length | Locus description |
|
451 | YBR252W | 147 | YBR252W DUT1 SGDID:S000000456, Chr II from 722611-723054, Genome Release 64-1-1, Verified ORF, "deoxyuridine triphosphate diphosphatase (dUTPase); catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability; also has diphosphatase activity on deoxyinosine triphosphate" |
|
452 | YBR253W | 121 | YBR253W SRB6 SGDID:S000000457, Chr II from 723270-723635, Genome Release 64-1-1, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
|
453 | YBR254C | 175 | YBR254C TRS20 SGDID:S000000458, Chr II from 724263-723736, Genome Release 64-1-1, reverse complement, Verified ORF, "One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder" |
|
454 | YBR255C-A | 120 | YBR255C-A YBR255C-A SGDID:S000007649, Chr II from 726917-726618,727074-727012, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; may interact with respiratory chain complexes III (ubiquinol-cytochrome c reductase) or IV (cytochrome c oxidase); identified by sequence comparison with hemiascomycetous yeast species" |
|
455 | YBR255W | 694 | YBR255W MTC4 SGDID:S000000459, Chr II from 724456-726540, Genome Release 64-1-1, Verified ORF, "Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1" |
|
456 | YBR256C | 238 | YBR256C RIB5 SGDID:S000000460, Chr II from 728102-727386, Genome Release 64-1-1, reverse complement, Verified ORF, "Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway" |
|
457 | YBR257W | 279 | YBR257W POP4 SGDID:S000000461, Chr II from 728885-729724, Genome Release 64-1-1, Verified ORF, "Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; binds to the RPR1 RNA subunit in RNase P" |
|
458 | YBR258C | 142 | YBR258C SHG1 SGDID:S000000462, Chr II from 730162-729734, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres" |
|
459 | YBR259W | 688 | YBR259W YBR259W SGDID:S000000463, Chr II from 730387-732453, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; YBR259W is not an essential gene" |
|
460 | YBR260C | 666 | YBR260C RGD1 SGDID:S000000464, Chr II from 734639-732639, Genome Release 64-1-1, reverse complement, Verified ORF, "GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization" |
|
461 | YBR261C | 232 | YBR261C TAE1 SGDID:S000000465, Chr II from 735530-734832, Genome Release 64-1-1, reverse complement, Verified ORF, "AdoMet-dependent proline methyltransferase; catalyzes the dimethylation of ribosomal proteins Rpl12 and Rps25 at N-terminal proline residues; has a role in protein synthesis; fusion protein localizes to the cytoplasm" |
|
462 | YBR262C | 106 | YBR262C AIM5 SGDID:S000000466, Chr II from 736040-735720, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss" |
|
463 | YBR263W | 490 | YBR263W SHM1 SGDID:S000000467, Chr II from 736264-737736, Genome Release 64-1-1, Verified ORF, "Mitochondrial serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis; reverse reaction generates serine" |
|
464 | YBR264C | 199 | YBR264C YPT10 SGDID:S000000468, Chr II from 738369-737770, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTP-binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles" |
|
465 | YBR265W | 320 | YBR265W TSC10 SGDID:S000000469, Chr II from 738582-739544, Genome Release 64-1-1, Verified ORF, "3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family" |
|
466 | YBR267W | 393 | YBR267W REI1 SGDID:S000000471, Chr II from 739841-741022, Genome Release 64-1-1, Verified ORF, "Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network" |
|
467 | YBR268W | 105 | YBR268W MRPL37 SGDID:S000000472, Chr II from 741299-741616, Genome Release 64-1-1, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
|
468 | YBR269C | 138 | YBR269C FMP21 SGDID:S000000473, Chr II from 742576-742160, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
|
469 | YBR270C | 545 | YBR270C BIT2 SGDID:S000000474, Chr II from 744398-742761, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Subunit of TORC2, a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; similar to Bit61p" |
|
470 | YBR271W | 419 | YBR271W YBR271W SGDID:S000000475, Chr II from 744852-746111, Genome Release 64-1-1, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; predicted to be involved in ribosome biogenesis" |
|
471 | YBR272C | 480 | YBR272C HSM3 SGDID:S000000476, Chr II from 747803-746361, Genome Release 64-1-1, reverse complement, Verified ORF, "Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); involved in DNA mismatch repair during slow growth; weak similarity to Msh1p; related to human 19S subunit S5b" |
|
472 | YBR273C | 436 | YBR273C UBX7 SGDID:S000000477, Chr II from 749371-748061, Genome Release 64-1-1, reverse complement, Verified ORF, "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p" |
|
473 | YBR274W | 527 | YBR274W CHK1 SGDID:S000000478, Chr II from 749594-751177, Genome Release 64-1-1, Verified ORF, "Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase" |
|
474 | YBR275C | 1916 | YBR275C RIF1 SGDID:S000000479, Chr II from 757106-751356, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation" |
|
475 | YBR276C | 807 | YBR276C PPS1 SGDID:S000000480, Chr II from 760043-757620, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle" |
|
476 | YBR278W | 201 | YBR278W DPB3 SGDID:S000000482, Chr II from 760294-760899, Genome Release 64-1-1, Verified ORF, "Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle" |
|
477 | YBR279W | 445 | YBR279W PAF1 SGDID:S000000483, Chr II from 761257-762594, Genome Release 64-1-1, Verified ORF, "Component of the Paf1p complex; binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cell cycle-regulated genes; homolog of human PD2/hPAF1; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay" |
|
478 | YBR280C | 637 | YBR280C SAF1 SGDID:S000000484, Chr II from 764697-762784, Genome Release 64-1-1, reverse complement, Verified ORF, "F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1" |
|
479 | YBR281C | 878 | YBR281C DUG2 SGDID:S000000485, Chr II from 767606-764970, Genome Release 64-1-1, reverse complement, Verified ORF, "Probable di- and tri-peptidase; forms a complex with Dug1p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)" |
|
480 | YBR282W | 146 | YBR282W MRPL27 SGDID:S000000486, Chr II from 768240-768680, Genome Release 64-1-1, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |