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1 | Locus | Length | Locus description |
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3901 | YLR352W | 807 | YLR352W YLR352W SGDID:S000004344, Chr XII from 831116-833539, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function with similarity to F-box proteins; interacts with Skp1p and Cdc53p; YLR352W is not an essential gene" |
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3902 | YLR353W | 603 | YLR353W BUD8 SGDID:S000004345, Chr XII from 834352-836163, Genome Release 64-1-1, Verified ORF, "Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole" |
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3903 | YLR354C | 335 | YLR354C TAL1 SGDID:S000004346, Chr XII from 837357-836350, Genome Release 64-1-1, reverse complement, Verified ORF, "Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate" |
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3904 | YLR355C | 395 | YLR355C ILV5 SGDID:S000004347, Chr XII from 839253-838066, Genome Release 64-1-1, reverse complement, Verified ORF, "Bifunctional acetohydroxyacid reductoisomerase and mtDNA binding protein; involved in branched-chain amino acid biosynthesis and maintenance of wild-type mitochondrial DNA; found in mitochondrial nucleoids" |
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3905 | YLR356W | 197 | YLR356W ATG33 SGDID:S000004348, Chr XII from 840321-840914, Genome Release 64-1-1, Verified ORF, "Mitochondrial mitophagy-specific protein; required primarily for mitophagy induced at the post-log phase; not required for other types of selective autophagy or macroautophagy; conserved within fungi, but not in higher eukaryotes" |
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3906 | YLR357W | 889 | YLR357W RSC2 SGDID:S000004349, Chr XII from 841331-844000, Genome Release 64-1-1, Verified ORF, "Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance" |
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3907 | YLR359W | 482 | YLR359W ADE13 SGDID:S000004351, Chr XII from 844282-845730, Genome Release 64-1-1, Verified ORF, "Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency" |
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3908 | YLR360W | 439 | YLR360W VPS38 SGDID:S000004352, Chr XII from 846103-847422, Genome Release 64-1-1, Verified ORF, "Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxypeptidase Y (CPY) sorting; binds Vps30p and Vps34p to promote production of phosphatidylinositol 3-phosphate (PtdIns3P) which stimulates kinase activity" |
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3909 | YLR361C | 578 | YLR361C DCR2 SGDID:S000004353, Chr XII from 849124-847388, Genome Release 64-1-1, reverse complement, Verified ORF, "Phosphoesterase involved in downregulation of the unfolded protein response, at least in part via dephosphorylation of Ire1p; dosage-dependent positive regulator of the G1/S phase transition through control of the timing of START" |
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3910 | YLR361C-A | 98 | YLR361C-A YLR361C-A SGDID:S000028845, Chr XII from 849679-849383, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
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3911 | YLR362W | 717 | YLR362W STE11 SGDID:S000004354, Chr XII from 849866-852019, Genome Release 64-1-1, Verified ORF, "Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p" |
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3912 | YLR363C | 218 | YLR363C NMD4 SGDID:S000004355, Chr XII from 853151-852495, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein interacting with Nam7p, may be involved in the nonsense-mediated mRNA decay pathway" |
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3913 | YLR363W-A | 85 | YLR363W-A YLR363W-A SGDID:S000007620, Chr XII from 853461-853718, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" |
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3914 | YLR364W | 109 | YLR364W GRX8 SGDID:S000004356, Chr XII from 854062-854391, Genome Release 64-1-1, Verified ORF, "Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic" |
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3915 | YLR367W | 130 | YLR367W RPS22B SGDID:S000004359, Chr XII from 856442-856574,857058-857317, Genome Release 64-1-1, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins" |
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3916 | YLR368W | 598 | YLR368W MDM30 SGDID:S000004360, Chr XII from 857540-859336, Genome Release 64-1-1, Verified ORF, "F-box component of an SCF ubiquitin protein ligase complex; associates with and is required for Fzo1p ubiquitination and for mitochondria fusion; stimulates nuclear export of specific mRNAs; promotes ubiquitin-mediated degradation of Gal4p in some strains" |
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3917 | YLR369W | 657 | YLR369W SSQ1 SGDID:S000004361, Chr XII from 859552-861525, Genome Release 64-1-1, Verified ORF, "Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia" |
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3918 | YLR370C | 178 | YLR370C ARC18 SGDID:S000004362, Chr XII from 862254-861718, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" |
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3919 | YLR371W | 1356 | YLR371W ROM2 SGDID:S000004363, Chr XII from 862714-866784, Genome Release 64-1-1, Verified ORF, "GDP/GTP exchange factor (GEF) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEF" |
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3920 | YLR372W | 345 | YLR372W SUR4 SGDID:S000004364, Chr XII from 867354-868391, Genome Release 64-1-1, Verified ORF, "Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis" |
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3921 | YLR373C | 901 | YLR373C VID22 SGDID:S000004365, Chr XII from 871367-868662, Genome Release 64-1-1, reverse complement, Verified ORF, "Glycosylated integral membrane protein localized to the plasma membrane; plays a role in fructose-1,6-bisphosphatase (FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles" |
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3922 | YLR375W | 343 | YLR375W STP3 SGDID:S000004367, Chr XII from 871697-872728, Genome Release 64-1-1, Verified ORF, "Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids" |
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3923 | YLR376C | 242 | YLR376C PSY3 SGDID:S000004368, Chr XII from 873554-872826, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair; deletion results in a mutator phenotype; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C" |
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3924 | YLR377C | 348 | YLR377C FBP1 SGDID:S000004369, Chr XII from 874792-873746, Genome Release 64-1-1, reverse complement, Verified ORF, "Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; interacts with Vid30p" |
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3925 | YLR378C | 480 | YLR378C SEC61 SGDID:S000004370, Chr XII from 877178-875736, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER" |
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3926 | YLR380W | 408 | YLR380W CSR1 SGDID:S000004372, Chr XII from 878282-879508, Genome Release 64-1-1, Verified ORF, "Phosphatidylinositol transfer protein with a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance" |
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3927 | YLR381W | 733 | YLR381W CTF3 SGDID:S000004373, Chr XII from 879723-881924, Genome Release 64-1-1, Verified ORF, "Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to spindle microtubules" |
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3928 | YLR382C | 894 | YLR382C NAM2 SGDID:S000004374, Chr XII from 884751-882067, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance" |
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3929 | YLR383W | 1114 | YLR383W SMC6 SGDID:S000004375, Chr XII from 885288-888632, Genome Release 64-1-1, Verified ORF, "Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 complex; required for growth, DNA repair, interchromosomal and sister chromatid recombination; homologous to S. pombe rad18" |
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3930 | YLR384C | 1349 | YLR384C IKI3 SGDID:S000004376, Chr XII from 892900-888851, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)" |