|
1 | Locus | Length | Locus description |
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3391 | YKL213C | 715 | YKL213C DOA1 SGDID:S000001696, Chr XI from 34107-31960, Genome Release 64-1-1, reverse complement, Verified ORF, "WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase" |
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3392 | YKL214C | 203 | YKL214C YRA2 SGDID:S000001697, Chr XI from 31693-31082, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus" |
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3393 | YKL215C | 1286 | YKL215C OXP1 SGDID:S000001698, Chr XI from 30687-26827, Genome Release 64-1-1, reverse complement, Verified ORF, "5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
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3394 | YKL216W | 314 | YKL216W URA1 SGDID:S000001699, Chr XI from 25215-26159, Genome Release 64-1-1, Verified ORF, "Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid" |
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3395 | YKL217W | 616 | YKL217W JEN1 SGDID:S000001700, Chr XI from 22234-24084, Genome Release 64-1-1, Verified ORF, "Monocarboxylate/proton symporter of the plasma membrane; transport activity is dependent on the pH gradient across the membrane; mediates high-affinity uptake of carbon sources lactate, pyuvate, and acetate, and also of the micronutrient selenite, whose structure mimics that of monocarboxylates; expression and localization are tightly regulated, with transcription repression, mRNA degradation, and protein endocytosis and degradation all occurring in the presence of glucose" |
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3396 | YKL218C | 326 | YKL218C SRY1 SGDID:S000001701, Chr XI from 18339-17359, Genome Release 64-1-1, reverse complement, Verified ORF, "3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required in the presence of hydroxyaspartate; highly similar to mouse serine racemase (Srr) but has no serine racemase activity" |
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3397 | YKL219W | 407 | YKL219W COS9 SGDID:S000001702, Chr XI from 14485-15708, Genome Release 64-1-1, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
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3398 | YKL220C | 711 | YKL220C FRE2 SGDID:S000001703, Chr XI from 11226-9091, Genome Release 64-1-1, reverse complement, Verified ORF, "Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels" |
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3399 | YKL221W | 473 | YKL221W MCH2 SGDID:S000001704, Chr XI from 6107-7528, Genome Release 64-1-1, Verified ORF, "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" |
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3400 | YKL222C | 705 | YKL222C YKL222C SGDID:S000001705, Chr XI from 5620-3503, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; similar to transcriptional regulators from the zinc cluster (binuclear cluster) family; null mutant is sensitive to caffeine" |
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3401 | YKL224C | 123 | YKL224C PAU16 SGDID:S000001707, Chr XI from 2181-1810, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions" |
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3402 | YKR001C | 704 | YKR001C VPS1 SGDID:S000001709, Chr XI from 442722-440608, Genome Release 64-1-1, reverse complement, Verified ORF, "Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization, endocytosis, late Golgi-retention of some proteins, regulation of peroxisome biogenesis" |
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3403 | YKR002W | 568 | YKR002W PAP1 SGDID:S000001710, Chr XI from 443232-444938, Genome Release 64-1-1, Verified ORF, "Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs; required for gene looping" |
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3404 | YKR003W | 448 | YKR003W OSH6 SGDID:S000001711, Chr XI from 445381-446727, Genome Release 64-1-1, Verified ORF, "Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery" |
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3405 | YKR004C | 377 | YKR004C ECM9 SGDID:S000001712, Chr XI from 447706-446799,448036-447811, Genome Release 64-1-1, reverse complement, Verified ORF, "Non-essential protein of unknown function" |
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3406 | YKR005C | 525 | YKR005C YKR005C SGDID:S000001713, Chr XI from 449951-448521,450167-450021, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
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3407 | YKR006C | 264 | YKR006C MRPL13 SGDID:S000001714, Chr XI from 451217-450423, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" |
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3408 | YKR007W | 184 | YKR007W MEH1 SGDID:S000001715, Chr XI from 451434-451988, Genome Release 64-1-1, Verified ORF, "Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification" |
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3409 | YKR008W | 625 | YKR008W RSC4 SGDID:S000001716, Chr XI from 452201-454078, Genome Release 64-1-1, Verified ORF, "Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p" |
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3410 | YKR009C | 900 | YKR009C FOX2 SGDID:S000001717, Chr XI from 457054-454352, Genome Release 64-1-1, reverse complement, Verified ORF, "Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities" |
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3411 | YKR010C | 771 | YKR010C TOF2 SGDID:S000001718, Chr XI from 461239-458924, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for rDNA silencing and mitotic rDNA condensation; stimulates Cdc14p phosphatase activity and biphasic release to promote rDNA repeat segregation; required for condensin recruitment to the replication fork barrier site" |
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3412 | YKR011C | 353 | YKR011C YKR011C SGDID:S000001719, Chr XI from 462696-461635, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" |
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3413 | YKR013W | 329 | YKR013W PRY2 SGDID:S000001721, Chr XI from 463959-464948, Genome Release 64-1-1, Verified ORF, "Protein of unknown function" |
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3414 | YKR014C | 234 | YKR014C YPT52 SGDID:S000001722, Chr XI from 466071-465367, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis" |
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3415 | YKR015C | 568 | YKR015C YKR015C SGDID:S000001723, Chr XI from 468667-466961, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
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3416 | YKR016W | 540 | YKR016W FCJ1 SGDID:S000001724, Chr XI from 469717-471339, Genome Release 64-1-1, Verified ORF, "Mitochondrial inner membrane protein involved in formation and molecular structure of crista junctions; impairs oligomerization of F1F0-ATP synthase; null shows altered mitochondrial morphology and abnormal mitochondrial genome maintenance" |
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3417 | YKR017C | 551 | YKR017C YKR017C SGDID:S000001725, Chr XI from 473349-471694, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; contains a RING finger motif" |
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3418 | YKR018C | 725 | YKR018C YKR018C SGDID:S000001726, Chr XI from 475900-473723, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
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3419 | YKR019C | 615 | YKR019C IRS4 SGDID:S000001727, Chr XI from 478063-476216, Genome Release 64-1-1, reverse complement, Verified ORF, "EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS" |
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3420 | YKR020W | 164 | YKR020W VPS51 SGDID:S000001728, Chr XI from 478338-478832, Genome Release 64-1-1, Verified ORF, "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; links the (VFT/GARP) complex to the SNARE Tlg1p" |