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1 | Locus | Length | Locus description |
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3301 | YKL112W | 731 | YKL112W ABF1 SGDID:S000001595, Chr XI from 226570-228765, Genome Release 64-1-1, Verified ORF, "DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair" |
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3302 | YKL113C | 382 | YKL113C RAD27 SGDID:S000001596, Chr XI from 225875-224727, Genome Release 64-1-1, reverse complement, Verified ORF, "5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family" |
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3303 | YKL114C | 367 | YKL114C APN1 SGDID:S000001597, Chr XI from 224455-223352, Genome Release 64-1-1, reverse complement, Verified ORF, "Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine" |
![Ortho button](graphics/orthoButton.png) |
3304 | YKL116C | 518 | YKL116C PRR1 SGDID:S000001599, Chr XI from 222900-221344, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor" |
![Ortho button](graphics/orthoButton.png) |
3305 | YKL117W | 216 | YKL117W SBA1 SGDID:S000001600, Chr XI from 220324-220974, Genome Release 64-1-1, Verified ORF, "Co-chaperone that binds to and regulates Hsp90 family chaperones; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins and like p23 can regulate telomerase activity" |
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3306 | YKL119C | 215 | YKL119C VPH2 SGDID:S000001602, Chr XI from 219217-218570, Genome Release 64-1-1, reverse complement, Verified ORF, "Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)" |
![Ortho button](graphics/orthoButton.png) |
3307 | YKL120W | 324 | YKL120W OAC1 SGDID:S000001603, Chr XI from 217344-218318, Genome Release 64-1-1, Verified ORF, "Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, thiosulfate, and isopropylmalate; member of the mitochondrial carrier family" |
![Ortho button](graphics/orthoButton.png) |
3308 | YKL121W | 852 | YKL121W DGR2 SGDID:S000001604, Chr XI from 214142-216700, Genome Release 64-1-1, Uncharacterized ORF, "Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds" |
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3309 | YKL122C | 167 | YKL122C SRP21 SGDID:S000001605, Chr XI from 212998-212495, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm" |
![Ortho button](graphics/orthoButton.png) |
3310 | YKL124W | 579 | YKL124W SSH4 SGDID:S000001607, Chr XI from 210593-212332, Genome Release 64-1-1, Verified ORF, "Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the multivesicular body; identified as a high-copy suppressor of a SHR3 deletion, increasing steady-state levels of amino acid permeases" |
![Ortho button](graphics/orthoButton.png) |
3311 | YKL125W | 627 | YKL125W RRN3 SGDID:S000001608, Chr XI from 208247-210130, Genome Release 64-1-1, Verified ORF, "Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA" |
![Ortho button](graphics/orthoButton.png) |
3312 | YKL126W | 680 | YKL126W YPK1 SGDID:S000001609, Chr XI from 205707-207749, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase that phosphorylates and downregulates flippase activator Fpk1p; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK" |
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3313 | YKL127W | 570 | YKL127W PGM1 SGDID:S000001610, Chr XI from 203541-205253, Genome Release 64-1-1, Verified ORF, "Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism" |
![Ortho button](graphics/orthoButton.png) |
3314 | YKL128C | 295 | YKL128C PMU1 SGDID:S000001611, Chr XI from 201771-200884, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant" |
![Ortho button](graphics/orthoButton.png) |
3315 | YKL129C | 1272 | YKL129C MYO3 SGDID:S000001612, Chr XI from 200167-196349, Genome Release 64-1-1, reverse complement, Verified ORF, "One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization" |
![Ortho button](graphics/orthoButton.png) |
3316 | YKL130C | 246 | YKL130C SHE2 SGDID:S000001613, Chr XI from 196028-195288, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud" |
![Ortho button](graphics/orthoButton.png) |
3317 | YKL132C | 430 | YKL132C RMA1 SGDID:S000001615, Chr XI from 194866-193574, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative dihydrofolate synthetase; has similarity to Fol3p and to E. coli folylpolyglutamate synthetase/dihydrofolate synthetase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
![Ortho button](graphics/orthoButton.png) |
3318 | YKL133C | 463 | YKL133C YKL133C SGDID:S000001616, Chr XI from 193070-191679, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; has similarity to Mgr3p, but unlike MGR3, is not required for growth of cells lacking the mitochondrial genome (null mutation does not confer a petite-negative phenotype)" |
![Ortho button](graphics/orthoButton.png) |
3319 | YKL134C | 772 | YKL134C OCT1 SGDID:S000001617, Chr XI from 191442-189124, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial intermediate peptidase, cleaves destabilizing N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis" |
![Ortho button](graphics/orthoButton.png) |
3320 | YKL135C | 726 | YKL135C APL2 SGDID:S000001618, Chr XI from 188640-186460, Genome Release 64-1-1, reverse complement, Verified ORF, "Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting" |
![Ortho button](graphics/orthoButton.png) |
3321 | YKL137W | 111 | YKL137W CMC1 SGDID:S000001620, Chr XI from 185957-186292, Genome Release 64-1-1, Verified ORF, "Evolutionarily conserved copper-binding protein of the mitochondrial intermembrane space, may be involved in delivering copper from the matrix to the cytochrome c oxidase complex; contains a twin CX9C motif" |
![Ortho button](graphics/orthoButton.png) |
3322 | YKL138C | 131 | YKL138C MRPL31 SGDID:S000001621, Chr XI from 185681-185286, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
![Ortho button](graphics/orthoButton.png) |
3323 | YKL138C-A | 69 | YKL138C-A HSK3 SGDID:S000028421, Chr XI from 185012-184803, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" |
![Ortho button](graphics/orthoButton.png) |
3324 | YKL139W | 528 | YKL139W CTK1 SGDID:S000001622, Chr XI from 182958-184544, Genome Release 64-1-1, Verified ORF, "Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13" |
![Ortho button](graphics/orthoButton.png) |
3325 | YKL140W | 548 | YKL140W TGL1 SGDID:S000001623, Chr XI from 180779-182425, Genome Release 64-1-1, Verified ORF, "Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes" |
![Ortho button](graphics/orthoButton.png) |
3326 | YKL141W | 198 | YKL141W SDH3 SGDID:S000001624, Chr XI from 179667-180263, Genome Release 64-1-1, Verified ORF, "Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain" |
![Ortho button](graphics/orthoButton.png) |
3327 | YKL142W | 219 | YKL142W MRP8 SGDID:S000001625, Chr XI from 178515-179174, Genome Release 64-1-1, Verified ORF, "Protein of unknown function; undergoes sumoylation; transcription induced under cell wall stress; protein levels are reduced under anaerobic conditions; originally thought to be a mitochondrial ribosomal protein based on sequence analysis" |
![Ortho button](graphics/orthoButton.png) |
3328 | YKL143W | 463 | YKL143W LTV1 SGDID:S000001626, Chr XI from 176781-178172, Genome Release 64-1-1, Verified ORF, "Component of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; required for ribosomal small subunit export from nucleus; required for growth at low temperature" |
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3329 | YKL144C | 212 | YKL144C RPC25 SGDID:S000001627, Chr XI from 176481-175843, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA polymerase III subunit C25, required for transcription initiation; forms a heterodimer with Rpc17p; paralog of Rpb7p" |
![Ortho button](graphics/orthoButton.png) |
3330 | YKL145W | 467 | YKL145W RPT1 SGDID:S000001628, Chr XI from 174213-175616, Genome Release 64-1-1, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance" |