|
1 | Locus | Length | Locus description |
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301 | YBR097W | 1454 | YBR097W VPS15 SGDID:S000000301, Chr II from 436951-441315, Genome Release 64-1-1, Verified ORF, "Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p" |
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302 | YBR098W | 691 | YBR098W MMS4 SGDID:S000000302, Chr II from 441515-443590, Genome Release 64-1-1, Verified ORF, "Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination, DNA repair, and joint molecule formation/resolution during meiotic recombination" |
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303 | YBR101C | 290 | YBR101C FES1 SGDID:S000000305, Chr II from 444693-443821, Genome Release 64-1-1, reverse complement, Verified ORF, "Hsp70 (Ssa1p) nucleotide exchange factor, cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum" |
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304 | YBR102C | 753 | YBR102C EXO84 SGDID:S000000306, Chr II from 447323-445062, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis" |
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305 | YBR103W | 535 | YBR103W SIF2 SGDID:S000000307, Chr II from 447709-449316, Genome Release 64-1-1, Verified ORF, "WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus" |
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306 | YBR104W | 329 | YBR104W YMC2 SGDID:S000000308, Chr II from 449667-450656, Genome Release 64-1-1, Verified ORF, "Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc1p" |
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307 | YBR105C | 362 | YBR105C VID24 SGDID:S000000309, Chr II from 451969-450881, Genome Release 64-1-1, reverse complement, Verified ORF, "Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; promotes proteasome-dependent catabolite degradation of FBPase" |
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308 | YBR106W | 188 | YBR106W PHO88 SGDID:S000000310, Chr II from 452658-453224, Genome Release 64-1-1, Verified ORF, "Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations" |
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309 | YBR107C | 245 | YBR107C IML3 SGDID:S000000311, Chr II from 454530-453793, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein with a role in kinetochore function, localizes to the outer kinetochore in a Ctf19p-dependent manner, interacts with Chl4p and Ctf19p" |
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310 | YBR108W | 947 | YBR108W AIM3 SGDID:S000000312, Chr II from 454822-457665, Genome Release 64-1-1, Verified ORF, "Protein interacting with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss" |
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311 | YBR109C | 147 | YBR109C CMD1 SGDID:S000000313, Chr II from 458362-457919, Genome Release 64-1-1, reverse complement, Verified ORF, "Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin" |
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312 | YBR110W | 449 | YBR110W ALG1 SGDID:S000000314, Chr II from 458872-460221, Genome Release 64-1-1, Verified ORF, "Mannosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability, mutation is functionally complemented by human ortholog" |
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313 | YBR111C | 231 | YBR111C YSA1 SGDID:S000000315, Chr II from 461873-461178, Genome Release 64-1-1, reverse complement, Verified ORF, "Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; shown to metabolize O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate" |
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314 | YBR111W-A | 96 | YBR111W-A SUS1 SGDID:S000028510, Chr II from 462139-462209,462290-462429,462500-462579, Genome Release 64-1-1, Verified ORF, "Component of both the SAGA histone acetylase and TREX-2 complexes; interacts with RNA polymerase II; involved in mRNA export coupled transcription activation and elongation; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP" |
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315 | YBR112C | 966 | YBR112C CYC8 SGDID:S000000316, Chr II from 465770-462870, Genome Release 64-1-1, reverse complement, Verified ORF, "General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+]" |
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316 | YBR114W | 790 | YBR114W RAD16 SGDID:S000000318, Chr II from 467248-469620, Genome Release 64-1-1, Verified ORF, "Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex" |
![Ortho button](graphics/orthoButton.png) |
317 | YBR115C | 1392 | YBR115C LYS2 SGDID:S000000319, Chr II from 473926-469748, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p" |
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318 | YBR117C | 681 | YBR117C TKL2 SGDID:S000000321, Chr II from 476437-474392, Genome Release 64-1-1, reverse complement, Verified ORF, "Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids" |
![Ortho button](graphics/orthoButton.png) |
319 | YBR118W | 458 | YBR118W TEF2 SGDID:S000000322, Chr II from 477671-479047, Genome Release 64-1-1, Verified ORF, "Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes; may also have a role in tRNA re-export from the nucleus" |
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320 | YBR119W | 298 | YBR119W MUD1 SGDID:S000000323, Chr II from 479338-479345,479435-480323, Genome Release 64-1-1, Verified ORF, "U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing" |
![Ortho button](graphics/orthoButton.png) |
321 | YBR120C | 162 | YBR120C CBP6 SGDID:S000000324, Chr II from 480923-480435, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial protein required for translation of the COB mRNA; forms a complex with Cbp3p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex" |
![Ortho button](graphics/orthoButton.png) |
322 | YBR121C | 667 | YBR121C GRS1 SGDID:S000000325, Chr II from 483367-481364, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation" |
![Ortho button](graphics/orthoButton.png) |
323 | YBR122C | 177 | YBR122C MRPL36 SGDID:S000000326, Chr II from 484503-483970, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region" |
![Ortho button](graphics/orthoButton.png) |
324 | YBR123C | 649 | YBR123C TFC1 SGDID:S000000327, Chr II from 486691-484742, Genome Release 64-1-1, reverse complement, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63" |
![Ortho button](graphics/orthoButton.png) |
325 | YBR125C | 393 | YBR125C PTC4 SGDID:S000000329, Chr II from 488380-487199, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity" |
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326 | YBR126C | 495 | YBR126C TPS1 SGDID:S000000330, Chr II from 490392-488905, Genome Release 64-1-1, reverse complement, Verified ORF, "Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway" |
![Ortho button](graphics/orthoButton.png) |
327 | YBR127C | 517 | YBR127C VMA2 SGDID:S000000331, Chr II from 492822-491269, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm" |
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328 | YBR128C | 344 | YBR128C ATG14 SGDID:S000000332, Chr II from 494115-493081, Genome Release 64-1-1, reverse complement, Verified ORF, "Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I (with Vps34/15/30p); Atg14p targets complex I to the phagophore assembly site (PAS); required for localizing additional ATG proteins to the PAS; homolog of human Barkor" |
![Ortho button](graphics/orthoButton.png) |
329 | YBR129C | 328 | YBR129C OPY1 SGDID:S000000333, Chr II from 495339-494353, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
![Ortho button](graphics/orthoButton.png) |
330 | YBR130C | 425 | YBR130C SHE3 SGDID:S000000334, Chr II from 496869-495592, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance" |