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1 | Locus | Length | Locus description |
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2461 | YHR059W | 130 | YHR059W FYV4 SGDID:S000001101, Chr VIII from 220108-220500, Genome Release 64-1-1, Verified ORF, "Protein of unknown function, required for survival upon exposure to K1 killer toxin" |
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2462 | YHR060W | 181 | YHR060W VMA22 SGDID:S000001102, Chr VIII from 220725-221270, Genome Release 64-1-1, Verified ORF, "Peripheral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)" |
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2463 | YHR061C | 314 | YHR061C GIC1 SGDID:S000001103, Chr VIII from 222478-221534, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain" |
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2464 | YHR062C | 293 | YHR062C RPP1 SGDID:S000001104, Chr VIII from 223758-222877, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs" |
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2465 | YHR063C | 379 | YHR063C PAN5 SGDID:S000001105, Chr VIII from 225169-224030, Genome Release 64-1-1, reverse complement, Verified ORF, "2-dehydropantoate 2-reductase, part of the pantothenic acid pathway, structurally homologous to E. coli panE" |
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2466 | YHR064C | 538 | YHR064C SSZ1 SGDID:S000001106, Chr VIII from 227141-225525, Genome Release 64-1-1, reverse complement, Verified ORF, "Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP" |
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2467 | YHR065C | 501 | YHR065C RRP3 SGDID:S000001107, Chr VIII from 229037-227532, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity" |
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2468 | YHR066W | 453 | YHR066W SSF1 SGDID:S000001108, Chr VIII from 229335-230696, Genome Release 64-1-1, Verified ORF, "Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family" |
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2469 | YHR067W | 280 | YHR067W HTD2 SGDID:S000001109, Chr VIII from 230970-231812, Genome Release 64-1-1, Verified ORF, "Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology" |
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2470 | YHR068W | 387 | YHR068W DYS1 SGDID:S000001110, Chr VIII from 232133-233296, Genome Release 64-1-1, Verified ORF, "Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric" |
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2471 | YHR069C | 359 | YHR069C RRP4 SGDID:S000001111, Chr VIII from 234658-233579, Genome Release 64-1-1, reverse complement, Verified ORF, "Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain RNA binding domains; has similarity to human hRrp4p (EXOSC2)" |
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2472 | YHR070W | 499 | YHR070W TRM5 SGDID:S000001112, Chr VIII from 234881-236380, Genome Release 64-1-1, Verified ORF, "tRNA(m(1)G37)methyltransferase, methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya" |
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2473 | YHR071W | 229 | YHR071W PCL5 SGDID:S000001113, Chr VIII from 237004-237693, Genome Release 64-1-1, Verified ORF, "Cyclin, interacts with and phosphorylated by Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity" |
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2474 | YHR072W | 731 | YHR072W ERG7 SGDID:S000001114, Chr VIII from 239098-241293, Genome Release 64-1-1, Verified ORF, "Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis" |
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2475 | YHR072W-A | 58 | YHR072W-A NOP10 SGDID:S000007455, Chr VIII from 241664-241840, Genome Release 64-1-1, Verified ORF, "Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA" |
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2476 | YHR073W | 996 | YHR073W OSH3 SGDID:S000001115, Chr VIII from 242582-245572, Genome Release 64-1-1, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" |
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2477 | YHR074W | 714 | YHR074W QNS1 SGDID:S000001116, Chr VIII from 246193-248337, Genome Release 64-1-1, Verified ORF, "Glutamine-dependent NAD(+) synthetase, essential for the formation of NAD(+) from nicotinic acid adenine dinucleotide" |
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2478 | YHR075C | 400 | YHR075C PPE1 SGDID:S000001117, Chr VIII from 249641-248439, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein" |
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2479 | YHR076W | 343 | YHR076W PTC7 SGDID:S000001118, Chr VIII from 251101-251155,251249-252225, Genome Release 64-1-1, Verified ORF, "Type 2C protein phosphatase (PP2C); alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope" |
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2480 | YHR077C | 1089 | YHR077C NMD2 SGDID:S000001119, Chr VIII from 255637-252374,255756-255751, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance" |
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2481 | YHR078W | 552 | YHR078W YHR078W SGDID:S000001120, Chr VIII from 256360-258018, Genome Release 64-1-1, Uncharacterized ORF, "High osmolarity-regulated gene of unknown function" |
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2482 | YHR079C | 1115 | YHR079C IRE1 SGDID:S000001121, Chr VIII from 261591-258244, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; Kar2p binds inactive Ire1p and releases from it upon ER stress" |
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2483 | YHR079C-A | 91 | YHR079C-A SAE3 SGDID:S000001957, Chr VIII from 262354-262192,262553-262441, Genome Release 64-1-1, reverse complement, Verified ORF, "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p" |
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2484 | YHR080C | 1345 | YHR080C YHR080C SGDID:S000001122, Chr VIII from 266838-262801, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
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2485 | YHR081W | 184 | YHR081W LRP1 SGDID:S000001123, Chr VIII from 267538-268092, Genome Release 64-1-1, Verified ORF, "Nuclear exosome-associated nucleic acid binding protein; involved in RNA processing, surveillance, degradation, tethering, and export; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination" |
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2486 | YHR082C | 1029 | YHR082C KSP1 SGDID:S000001124, Chr VIII from 271548-268459, Genome Release 64-1-1, reverse complement, Verified ORF, "Ser/thr protein kinase; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10" |
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2487 | YHR083W | 329 | YHR083W SAM35 SGDID:S000001125, Chr VIII from 272627-273616, Genome Release 64-1-1, Verified ORF, "Essential component of the sorting and assembly machinery (SAM complex or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane" |
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2488 | YHR084W | 688 | YHR084W STE12 SGDID:S000001126, Chr VIII from 274174-276240, Genome Release 64-1-1, Verified ORF, "Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth" |
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2489 | YHR085W | 334 | YHR085W IPI1 SGDID:S000001127, Chr VIII from 276764-277768, Genome Release 64-1-1, Verified ORF, "Essential component of the Rix1 complex (with Rix1p and Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles" |
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2490 | YHR086W | 523 | YHR086W NAM8 SGDID:S000001128, Chr VIII from 278153-279724, Genome Release 64-1-1, Verified ORF, "RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function" |