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1 | Locus | Length | Locus description |
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2401 | YHR005C | 472 | YHR005C GPA1 SGDID:S000001047, Chr VIII from 114917-113499, Genome Release 64-1-1, reverse complement, Verified ORF, "GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates Vps34p at the endosome" |
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2402 | YHR005C-A | 93 | YHR005C-A TIM10 SGDID:S000003530, Chr VIII from 115901-115620, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane" |
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2403 | YHR006W | 541 | YHR006W STP2 SGDID:S000001048, Chr VIII from 117814-119439, Genome Release 64-1-1, Verified ORF, "Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes" |
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2404 | YHR007C | 530 | YHR007C ERG11 SGDID:S000001049, Chr VIII from 121683-120091, Genome Release 64-1-1, reverse complement, Verified ORF, "Lanosterol 14-alpha-demethylase; catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p" |
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2405 | YHR007C-A | 71 | YHR007C-A YHR007C-A SGDID:S000028830, Chr VIII from 122765-122550, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
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2406 | YHR008C | 233 | YHR008C SOD2 SGDID:S000001050, Chr VIII from 123590-122889, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial manganese superoxide dismutase, protects cells against oxygen toxicity; phosphorylated" |
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2407 | YHR009C | 523 | YHR009C TDA3 SGDID:S000001051, Chr VIII from 125680-124109, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1" |
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2408 | YHR010W | 136 | YHR010W RPL27A SGDID:S000001052, Chr VIII from 126521-126551,127113-127492, Genome Release 64-1-1, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein" |
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2409 | YHR011W | 446 | YHR011W DIA4 SGDID:S000001053, Chr VIII from 127780-129120, Genome Release 64-1-1, Verified ORF, "Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive and pseudohyphal growth" |
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2410 | YHR012W | 282 | YHR012W VPS29 SGDID:S000001054, Chr VIII from 129481-129528,129648-130448, Genome Release 64-1-1, Verified ORF, "Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval" |
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2411 | YHR013C | 238 | YHR013C ARD1 SGDID:S000001055, Chr VIII from 131446-130730, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); acetylates many proteins and thus affects telomeric silencing, cell cycle, heat-shock resistance, mating, and sporulation; human Ard1p levels are elevated in cancer cells" |
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2412 | YHR014W | 291 | YHR014W SPO13 SGDID:S000001056, Chr VIII from 132047-132922, Genome Release 64-1-1, Verified ORF, "Meiosis-specific protein, involved in maintaining sister chromatid cohesion during meiosis I as well as promoting proper attachment of kinetochores to the spindle during meiosis I and meiosis II" |
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2413 | YHR015W | 659 | YHR015W MIP6 SGDID:S000001057, Chr VIII from 134554-136533, Genome Release 64-1-1, Verified ORF, "Putative RNA-binding protein, interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export" |
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2414 | YHR016C | 468 | YHR016C YSC84 SGDID:S000001058, Chr VIII from 138240-136881,138455-138409, Genome Release 64-1-1, reverse complement, Verified ORF, "Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p" |
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2415 | YHR017W | 385 | YHR017W YSC83 SGDID:S000001059, Chr VIII from 138694-139851, Genome Release 64-1-1, Verified ORF, "Non-essential mitochondrial protein of unknown function; mRNA induced during meiosis, peaking between mid to late prophase of meiosis I; similar to S. douglasii YSD83" |
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2416 | YHR018C | 463 | YHR018C ARG4 SGDID:S000001060, Chr VIII from 141402-140011, Genome Release 64-1-1, reverse complement, Verified ORF, "Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway" |
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2417 | YHR019C | 554 | YHR019C DED81 SGDID:S000001061, Chr VIII from 143558-141894, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA" |
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2418 | YHR020W | 688 | YHR020W YHR020W SGDID:S000001062, Chr VIII from 143996-146062, Genome Release 64-1-1, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to proline-tRNA ligase; YHR020W is an essential gene" |
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2419 | YHR021C | 82 | YHR021C RPS27B SGDID:S000001063, Chr VIII from 148116-147871,148669-148667, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein" |
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2420 | YHR021W-A | 151 | YHR021W-A ECM12 SGDID:S000003531, Chr VIII from 149225-149680, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; may contribute to cell wall biosynthesis, mutants display zymolyase hypersensitivity" |
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2421 | YHR022C | 256 | YHR022C YHR022C SGDID:S000001064, Chr VIII from 150345-149575, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YHR022C is not an essential gene" |
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2422 | YHR022C-A | 29 | YHR022C-A YHR022C-A SGDID:S000028645, Chr VIII from 151306-151217, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
![Ortho button](graphics/orthoButton.png) |
2423 | YHR023W | 1928 | YHR023W MYO1 SGDID:S000001065, Chr VIII from 151666-157452, Genome Release 64-1-1, Verified ORF, "Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively" |
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2424 | YHR024C | 482 | YHR024C MAS2 SGDID:S000001066, Chr VIII from 159192-157744, Genome Release 64-1-1, reverse complement, Verified ORF, "Larger subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins" |
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2425 | YHR025W | 357 | YHR025W THR1 SGDID:S000001067, Chr VIII from 159438-160511, Genome Release 64-1-1, Verified ORF, "Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway" |
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2426 | YHR026W | 213 | YHR026W VMA16 SGDID:S000001068, Chr VIII from 160844-161485, Genome Release 64-1-1, Verified ORF, "Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain" |
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2427 | YHR027C | 993 | YHR027C RPN1 SGDID:S000001069, Chr VIII from 164711-161730, Genome Release 64-1-1, reverse complement, Verified ORF, "Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein-protein interactions" |
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2428 | YHR028C | 818 | YHR028C DAP2 SGDID:S000001070, Chr VIII from 167434-164978, Genome Release 64-1-1, reverse complement, Verified ORF, "Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p" |
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2429 | YHR029C | 294 | YHR029C YHI9 SGDID:S000001071, Chr VIII from 168561-167677, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production" |
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2430 | YHR030C | 484 | YHR030C SLT2 SGDID:S000001072, Chr VIII from 170344-168890, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine MAP kinase; involved in regulating maintenance of cell wall integrity, progression through the cell cycle, and nuclear mRNA retention in heat shock; required for mitophagy and pexophagy; affects recruitment of mitochondria to the phagophore assembly site (PAS); regulated by the PKC1-mediated signaling pathway" |