Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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Genome Summary: Searched sequences
Species:
Saccharomyces cerevisiae S288C
Number of sequences:
5887
records
Previous ‹‹ ›› Next Total records: 0 2221 - 2250
1LocusLengthLocus description
Ortho button 2221YGR162W   952   YGR162W TIF4631 SGDID:S000003394, Chr VII from 824059-826917, Genome Release 64-1-1, Verified ORF, "Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit"   
Ortho button 2222YGR163W   341   YGR163W GTR2 SGDID:S000003395, Chr VII from 827552-828577, Genome Release 64-1-1, Verified ORF, "Putative GTP binding protein that negatively regulates Ran/Tc4 GTPase cycle; activates transcription; subunit of EGO and GSE complexes; required for sorting of Gap1p; localizes to cytoplasm and to chromatin; homolog of human RagC and RagD"   
Ortho button 2223YGR165W   345   YGR165W MRPS35 SGDID:S000003397, Chr VII from 829116-830153, Genome Release 64-1-1, Verified ORF, "Mitochondrial ribosomal protein of the small subunit; null mutant does not grow on glycerol, is sensitive to 2,4-dichlorophenol, and accumulates large lipid droplets"   
Ortho button 2224YGR166W   560   YGR166W TRS65 SGDID:S000003398, Chr VII from 830515-832197, Genome Release 64-1-1, Verified ORF, "Subunit of TRAPPII, a multimeric guanine nucleotide-exchange factor for Ypt1p; involved in intra-Golgi traffic and the retrograde pathway from the endosome to Golgi; role in cell wall beta-glucan biosynthesis and the stress response"   
Ortho button 2225YGR167W   233   YGR167W CLC1 SGDID:S000003399, Chr VII from 832456-833157, Genome Release 64-1-1, Verified ORF, "Clathrin light chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; thought to regulate clathrin function; two Clathrin heavy chains (CHC1) form the clathrin triskelion structural component"   
Ortho button 2226YGR168C   376   YGR168C YGR168C SGDID:S000003400, Chr VII from 834482-833352, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YGR168C is not an essential gene"   
Ortho button 2227YGR169C   404   YGR169C PUS6 SGDID:S000003401, Chr VII from 835903-834689, Genome Release 64-1-1, reverse complement, Verified ORF, "tRNA:pseudouridine synthase, catalyzes the conversion of uridine to pseudouridine at position 31 in cytoplasmic and mitochondrial tRNAs; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability"   
Ortho button 2228YGR169C-A   92   YGR169C-A YGR169C-A SGDID:S000028521, Chr VII from 836665-836387, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function"   
Ortho button 2229YGR170W   1138   YGR170W PSD2 SGDID:S000003402, Chr VII from 837142-840558, Genome Release 64-1-1, Verified ORF, "Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes, converts phosphatidylserine to phosphatidylethanolamine"   
Ortho button 2230YGR171C   575   YGR171C MSM1 SGDID:S000003403, Chr VII from 842551-840824, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p"   
Ortho button 2231YGR172C   248   YGR172C YIP1 SGDID:S000003404, Chr VII from 843591-842845, Genome Release 64-1-1, reverse complement, Verified ORF, "Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF4"   
Ortho button 2232YGR173W   368   YGR173W RBG2 SGDID:S000003405, Chr VII from 843854-844960, Genome Release 64-1-1, Verified ORF, "Protein with a role in translation; forms a complex with Gir2p; has similarity to mammalian developmentally regulated GTP-binding protein"   
Ortho button 2233YGR174C   170   YGR174C CBP4 SGDID:S000003406, Chr VII from 846405-845893, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial protein required for assembly of cytochrome bc1 complex; interacts with the Cbp3p-Cbp6p complex and newly synthesized cytochrome b (Cobp) to promote assembly of Cobp into the cytochrome bc1 complex"   
Ortho button 2234YGR174W-A   28   YGR174W-A YGR174W-A SGDID:S000028639, Chr VII from 846655-846741, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; predicted to have a role in cell budding based on computational "guilt by association" analysis"   
Ortho button 2235YGR175C   496   YGR175C ERG1 SGDID:S000003407, Chr VII from 848423-846933, Genome Release 64-1-1, reverse complement, Verified ORF, "Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine"   
Ortho button 2236YGR177C   535   YGR177C ATF2 SGDID:S000003409, Chr VII from 850436-848829, Genome Release 64-1-1, reverse complement, Verified ORF, "Alcohol acetyltransferase, may play a role in steroid detoxification; forms volatile esters during fermentation, which is important for brewing and winemaking"   
Ortho button 2237YGR178C   722   YGR178C PBP1 SGDID:S000003410, Chr VII from 853215-851047, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; similar to human ataxin-2; interacts with Pab1p to regulate mRNA polyadenylation; interacts with Mkt1p to regulate HO translation"   
Ortho button 2238YGR179C   406   YGR179C OKP1 SGDID:S000003411, Chr VII from 854895-853675, Genome Release 64-1-1, reverse complement, Verified ORF, "Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly"   
Ortho button 2239YGR180C   345   YGR180C RNR4 SGDID:S000003412, Chr VII from 856301-855264, Genome Release 64-1-1, reverse complement, Verified ORF, "Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits"   
Ortho button 2240YGR181W   105   YGR181W TIM13 SGDID:S000003413, Chr VII from 858287-858604, Genome Release 64-1-1, Verified ORF, "Mitochondrial intermembrane space protein, forms a complex with Tim8p that delivers a subset of hydrophobic proteins to the TIM22 complex for insertion into the inner membrane"   
Ortho button 2241YGR183C   66   YGR183C QCR9 SGDID:S000003415, Chr VII from 859260-859063,859476-859474, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex"   
Ortho button 2242YGR184C   1950   YGR184C UBR1 SGDID:S000003416, Chr VII from 865753-859901, Genome Release 64-1-1, reverse complement, Verified ORF, "E3 ubiquitin ligase (N-recognin), forms heterodimer with Rad6p to ubiquitinate substrates in the N-end rule pathway; regulates peptide transport via Cup9p ubiquitination; mutation in human UBR1 causes Johansson-Blizzard Syndrome (JBS)"   
Ortho button 2243YGR185C   394   YGR185C TYS1 SGDID:S000003417, Chr VII from 867520-866336, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic tyrosyl-tRNA synthetase, required for cytoplasmic protein synthesis; interacts with positions 34 and 35 of the tRNATyr anticodon; mutations in human ortholog YARS are associated with Charcot-Marie-Tooth (CMT) neuropathies"   
Ortho button 2244YGR186W   735   YGR186W TFG1 SGDID:S000003418, Chr VII from 867774-869981, Genome Release 64-1-1, Verified ORF, "TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74"   
Ortho button 2245YGR187C   394   YGR187C HGH1 SGDID:S000003419, Chr VII from 871416-870232, Genome Release 64-1-1, reverse complement, Verified ORF, "Nonessential protein of unknown function; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16)"   
Ortho button 2246YGR188C   1021   YGR188C BUB1 SGDID:S000003420, Chr VII from 875109-872044, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase involved in the cell cycle checkpoint into anaphase; forms complex with Mad1p and Bub3p crucial to preventing cell cycle progression into anaphase in the presence of spindle damage; CDC28-mediated phosphorylation at Bub1p-T566 is important for its degradation in anaphase and adaptation of the checkpoint to prolonged mitotic arrest, but not to its kinase activity or chromosome segregation function; associates with centromere DNA via Skp1p"   
Ortho button 2247YGR189C   507   YGR189C CRH1 SGDID:S000003421, Chr VII from 878192-876669, Genome Release 64-1-1, reverse complement, Verified ORF, "Chitin transglycosylase that functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress"   
Ortho button 2248YGR191W   603   YGR191W HIP1 SGDID:S000003423, Chr VII from 880420-882231, Genome Release 64-1-1, Verified ORF, "High-affinity histidine permease, also involved in the transport of manganese ions"   
Ortho button 2249YGR192C   332   YGR192C TDH3 SGDID:S000003424, Chr VII from 883810-882812, Genome Release 64-1-1, reverse complement, Verified ORF, "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall"   
Ortho button 2250YGR193C   410   YGR193C PDX1 SGDID:S000003425, Chr VII from 885741-884509, Genome Release 64-1-1, reverse complement, Verified ORF, "Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core"   
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