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1 | Locus | Length | Locus description |
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1291 | YDR406W | 1529 | YDR406W PDR15 SGDID:S000002814, Chr IV from 1279210-1283799, Genome Release 64-1-1, Verified ORF, "Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element" |
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1292 | YDR407C | 1289 | YDR407C TRS120 SGDID:S000002815, Chr IV from 1287938-1284069, Genome Release 64-1-1, reverse complement, Verified ORF, "One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic" |
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1293 | YDR408C | 214 | YDR408C ADE8 SGDID:S000002816, Chr IV from 1288859-1288215, Genome Release 64-1-1, reverse complement, Verified ORF, "Phosphoribosyl-glycinamide transformylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway" |
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1294 | YDR409W | 904 | YDR409W SIZ1 SGDID:S000002817, Chr IV from 1289406-1292120, Genome Release 64-1-1, Verified ORF, "SUMO/Smt3 ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to proteins; binds Ubc9p and may bind septins; specifically required for sumoylation of septins in vivo; localized to the septin ring" |
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1295 | YDR410C | 239 | YDR410C STE14 SGDID:S000002818, Chr IV from 1293091-1292372, Genome Release 64-1-1, reverse complement, Verified ORF, "Farnesyl cysteine-carboxyl methyltransferase, mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane" |
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1296 | YDR411C | 341 | YDR411C DFM1 SGDID:S000002819, Chr IV from 1294394-1293369, Genome Release 64-1-1, reverse complement, Verified ORF, "Endoplasmic reticulum (ER) localized protein involved in ER-associated protein degradation (ERAD), ER stress and homeostasis; interacts with components of ERAD-L and ERAD-C and Cdc48p; derlin-like family member similar to Der1p" |
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1297 | YDR412W | 235 | YDR412W RRP17 SGDID:S000002820, Chr IV from 1294693-1295400, Genome Release 64-1-1, Verified ORF, "Component of the pre-60S pre-ribosomal particle; required for cell viability under standard (aerobic) conditions but not under anaerobic conditions; exonuclease required for 5′ end processing of pre-60S ribosomal RNA" |
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1298 | YDR414C | 362 | YDR414C ERD1 SGDID:S000002822, Chr IV from 1296686-1295598, Genome Release 64-1-1, reverse complement, Verified ORF, "Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p)" |
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1299 | YDR415C | 374 | YDR415C YDR415C SGDID:S000002823, Chr IV from 1298161-1297037, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
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1300 | YDR416W | 859 | YDR416W SYF1 SGDID:S000002824, Chr IV from 1298432-1301011, Genome Release 64-1-1, Verified ORF, "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; homologs in human and C. elegans" |
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1301 | YDR418W | 165 | YDR418W RPL12B SGDID:S000002826, Chr IV from 1301616-1302113, Genome Release 64-1-1, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins" |
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1302 | YDR419W | 632 | YDR419W RAD30 SGDID:S000002827, Chr IV from 1303174-1305072, Genome Release 64-1-1, Verified ORF, "DNA polymerase eta, involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; mutations in human pol eta are responsible for XPV" |
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1303 | YDR420W | 1802 | YDR420W HKR1 SGDID:S000002828, Chr IV from 1306267-1311675, Genome Release 64-1-1, Verified ORF, "Mucin family member that functions as an osmosensor in the Sho1p-mediated HOG pathway with Msb2p; proposed to be a negative regulator of filamentous growth; mutant displays defects in beta-1,3 glucan synthesis and bud site selection" |
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1304 | YDR421W | 950 | YDR421W ARO80 SGDID:S000002829, Chr IV from 1312040-1314892, Genome Release 64-1-1, Verified ORF, "Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids" |
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1305 | YDR422C | 815 | YDR422C SIP1 SGDID:S000002830, Chr IV from 1317773-1315326, Genome Release 64-1-1, reverse complement, Verified ORF, "Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions" |
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1306 | YDR423C | 409 | YDR423C CAD1 SGDID:S000002831, Chr IV from 1319275-1318046, Genome Release 64-1-1, reverse complement, Verified ORF, "AP-1-like basic leucine zipper (bZIP) transcriptional activator involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA" |
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1307 | YDR424C | 92 | YDR424C DYN2 SGDID:S000002832, Chr IV from 1319617-1319387,1319720-1319698,1319841-1319817, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic light chain dynein, microtubule motor protein; proposed to be involved in the assembly of the nuclear pore complex" |
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1308 | YDR425W | 625 | YDR425W SNX41 SGDID:S000002833, Chr IV from 1320064-1321941, Genome Release 64-1-1, Verified ORF, "Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; interacts with Snx4p" |
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1309 | YDR427W | 393 | YDR427W RPN9 SGDID:S000002835, Chr IV from 1322205-1323386, Genome Release 64-1-1, Verified ORF, "Non-ATPase regulatory subunit of the 26S proteasome, has similarity to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects" |
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1310 | YDR428C | 261 | YDR428C BNA7 SGDID:S000002836, Chr IV from 1324239-1323454, Genome Release 64-1-1, reverse complement, Verified ORF, "Formylkynurenine formamidase, involved in the de novo biosynthesis of NAD from tryptophan via kynurenine" |
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1311 | YDR429C | 274 | YDR429C TIF35 SGDID:S000002837, Chr IV from 1325301-1324477, Genome Release 64-1-1, reverse complement, Verified ORF, "eIF3g subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for translation; stimulates resumption of ribosomal scanning during translation reinitiation" |
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1312 | YDR430C | 989 | YDR430C CYM1 SGDID:S000002838, Chr IV from 1328470-1325501, Genome Release 64-1-1, reverse complement, Verified ORF, "Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology" |
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1313 | YDR432W | 414 | YDR432W NPL3 SGDID:S000002840, Chr IV from 1328783-1330027, Genome Release 64-1-1, Verified ORF, "RNA-binding protein that promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; required for pre-mRNA splicing; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm" |
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1314 | YDR434W | 534 | YDR434W GPI17 SGDID:S000002842, Chr IV from 1331237-1332841, Genome Release 64-1-1, Verified ORF, "Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Sp homolog" |
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1315 | YDR435C | 328 | YDR435C PPM1 SGDID:S000002843, Chr IV from 1333969-1332983, Genome Release 64-1-1, reverse complement, Verified ORF, "Carboxyl methyltransferase, methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits" |
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1316 | YDR436W | 710 | YDR436W PPZ2 SGDID:S000002844, Chr IV from 1334821-1336953, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance" |
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1317 | YDR437W | 140 | YDR437W GPI19 SGDID:S000002845, Chr IV from 1337352-1337774, Genome Release 64-1-1, Verified ORF, "Subunit of GPI-GlcNAc transferase involved in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), which is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis, shares similarity with mammalian PIG-P" |
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1318 | YDR438W | 370 | YDR438W THI74 SGDID:S000002846, Chr IV from 1338274-1339386, Genome Release 64-1-1, Verified ORF, "Mitochondrial transporter repressible by thiamine" |
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1319 | YDR439W | 347 | YDR439W LRS4 SGDID:S000002847, Chr IV from 1339676-1340719, Genome Release 64-1-1, Verified ORF, "Nucleolar protein that forms a complex with Csm1p, and then Mam1p at kinetochores during meiosis I to mediate accurate homolog segregation; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation" |
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1320 | YDR440W | 582 | YDR440W DOT1 SGDID:S000002848, Chr IV from 1342493-1344241, Genome Release 64-1-1, Verified ORF, "Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic checkpoint control, and DNA damage response" |