Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YAL002W
Length:
1274
Number of sequences:
5887
Description:
YAL002W VPS8 SGDID:S000000002, Chr I from 143707-147531, Genome Release 64-1-1, Verified ORF, "Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P39702    1274   VPS8_YEAST Vacuolar protein sorting-associate...12740     2612     100     100GO:0033263; C:CORVET complex; IDA:SGD.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0005770; C:late endosome; IDA:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.
GO:0051020; F:GTPase binding; IDA:SGD.::GO:0043495; F:protein anchor; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.
2Q0P5W1    1427   VPS8_MOUSE Vacuolar protein sorting-associate...1620.39     38.9     22     42
GO:0008270; F:zinc ion binding; IEA:InterPro.
3Q8N3P4    1428   VPS8_HUMAN Vacuolar protein sorting-associate...3640.000000000000001     86.3     23     45
GO:0008270; F:zinc ion binding; IEA:InterPro.
4O13756    1272   VPS8_SCHPO Vacuolar protein sorting-associate...3500.00000003     62     23     40GO:0033263; C:CORVET complex; ISS:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0008270; F:zinc ion binding; NAS:PomBase.
GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0045324; P:late endosome to vacuole transport; ISS:PomBase.
5Q9W328    313   LST8_DROME Protein LST8 homolog OS=Drosophila...750.17     39.3     25     45GO:0005737; C:cytoplasm; ISS:UniProtKB.
6Q5KU39    853   VPS41_MOUSE Vacuolar protein sorting-associat...1950.2     39.7     21     40GO:0005769; C:early endosome; IDA:MGI.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005874; C:microtubule; IDA:MGI.
GO:0008017; F:microtubule binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
7P49754    854   VPS41_HUMAN Vacuolar protein sorting-associat...1950.51     38.5     21     40GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005798; C:Golgi-associated vesicle; IMP:UniProtKB.::GO:0030897; C:HOPS complex; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
8Q16MY0    659   WDR48_AEDAE WD repeat-containing protein 48 h...1450.59     38.1     26     41
9Q29HG9    315   LST8_DROPS Protein LST8 homolog OS=Drosophila...740.66     37.4     26     46GO:0005737; C:cytoplasm; ISS:UniProtKB.
10O13282    643   TAF5_SCHPO Transcription initiation factor TF...1230.78     37.7     24     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0000124; C:SAGA complex; IDA:PomBase.::GO:0005669; C:transcription factor TFIID complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0016573; P:histone acetylation; IC:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IC:PomBase.
11Q9BVC4    326   LST8_HUMAN Target of rapamycin complex subuni...981.2     36.6     24     42GO:0005829; C:cytosol; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0032008; P:positive regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.
12Q17QU5    326   LST8_BOVIN Target of rapamycin complex subuni...981.3     36.6     24     42GO:0005737; C:cytoplasm; ISS:UniProtKB.
13P38129    798   TAF5_YEAST Transcription initiation factor TF...362     36.6     39     61GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.::GO:0005669; C:transcription factor TFIID complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032947; F:protein complex scaffold; IMP:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0016573; P:histone acetylation; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IC:SGD.
14Q9P6N4    906   PEP5_SCHPO Vacuolar membrane protein pep5 OS=...832.3     36.2     28     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0000329; C:fungal-type vacuole membrane; ISS:PomBase.::GO:0030897; C:HOPS complex; ISS:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0006895; P:Golgi to endosome transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0045324; P:late endosome to vacuole transport; ISS:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0042144; P:vacuole fusion, non-autophagic; ISS:PomBase.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:PomBase.
15B0X2V9    670   WDR48_CULQU WD repeat-containing protein 48 h...1512.6     35.8     25     44
16Q9LW83    850   CE101_ARATH G-type lectin S-receptor-like ser...683.8     35.4     38     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0044459; C:plasma membrane part; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
17Q9DCJ1    326   LST8_MOUSE Target of rapamycin complex subuni...983.8     35     24     41
GO:0030838; P:positive regulation of actin filament polymerization; IMP:MGI.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.
18Q803V5    326   LST8_DANRE Target of rapamycin complex subuni...985.5     34.7     26     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
19Q5ZMM3    475   RHG15_CHICK Rho GTPase-activating protein 15 ...1005.8     34.7     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
20Q9R1F8    784   TLR2_CRIGR Toll-like receptor 2 OS=Cricetulus...1039     34.3     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
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