| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q4WY82 | 1121 | PPOC_ASPFU Linoleate 10R-lipoxygenase OS=A110... | 1101 | 0 | 1429 | 61 | 76 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.::GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 2 | B0Y6R2 | 1079 | PPOA_ASPFC Psi-producing oxygenase A OS=(Aspe... | 1068 | 0 | 1248 | 55 | 72 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0052878; F:linoleate 8R-lipoxygenase activity; IEA:EC.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 3 | Q4WPX2 | 1079 | PPOA_ASPFU Psi-producing oxygenase A OS=A1100... | 1068 | 0 | 1248 | 55 | 72 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0052878; F:linoleate 8R-lipoxygenase activity; IEA:EC.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 4 | G5EB19 | 1081 | PPOA_EMENI Psi-producing oxygenase A OS=194 /... | 1069 | 0 | 1210 | 54 | 70 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0052878; F:linoleate 8R-lipoxygenase activity; IEA:EC.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 5 | Q6RET3 | 1081 | PPOA_EMEND Psi-producing oxygenase A OS=Emeri... | 1069 | 0 | 1210 | 54 | 70 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0052878; F:linoleate 8R-lipoxygenase activity; IEA:EC.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 6 | Q9UUS2 | 1165 | LIDS_GAEGR Linoleate diol synthase OS=Gaeuman... | 1125 | 0 | 912 | 42 | 58 | | | | | | | | | | | GO:0052879; F:9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0052878; F:linoleate 8R-lipoxygenase activity; IEA:EC.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 7 | Q05769 | 604 | PGH2_MOUSE Prostaglandin G/H synthase 2 OS=Mu... | 402 | 5e-28 | 124 | 28 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:MGI. | | | | | | | | | | GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0042640; P:anagen; IMP:MGI.::GO:0050873; P:brown fat cell differentiation; IMP:BHF-UCL.::GO:0019371; P:cyclooxygenase pathway; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.::GO:0090336; P:positive regulation of brown fat cell differentiation; IMP:BHF-UCL.::GO:0031622; P:positive regulation of fever generation; IDA:BHF-UCL.::GO:0008217; P:regulation of blood pressure; IMP:MGI.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 8 | P35355 | 604 | PGH2_RAT Prostaglandin G/H synthase 2 OS=Ratt... | 400 | 3e-26 | 118 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; TAS:RGD.::GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IMP:RGD.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IDA:RGD.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:RGD.::GO:0030282; P:bone mineralization; IMP:MGI.::GO:0071318; P:cellular response to ATP; IEP:RGD.::GO:0071260; P:cellular response to mechanical stimulus; IEP:RGD.::GO:0034644; P:cellular response to UV; IEP:RGD.::GO:0019371; P:cyclooxygenase pathway; ISS:UniProtKB.::GO:0046697; P:decidualization; IMP:RGD.::GO:0007566; P:embryo implantation; IMP:RGD.::GO:0006954; P:inflammatory response; IMP:RGD.::GO:0007612; P:learning; IMP:RGD.::GO:0035633; P:maintenance of blood-brain barrier; IMP:RGD.::GO:0007613; P:memory; IMP:RGD.::GO:0051926; P:negative regulation of calcium ion transport; IMP:RGD.::GO:0045786; P:negative regulation of cell cycle; IGI:RGD.::GO:0008285; P:negative regulation of cell proliferation; IDA:RGD.::GO:0045986; P:negative regulation of smooth muscle contraction; IMP:RGD.::GO:0032227; P:negative regulation of synaptic transmission, dopaminergic; IMP:RGD.::GO:0030728; P:ovulation; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.::GO:0031622; P:positive regulation of fever generation; IDA:BHF-UCL.::GO:0090271; P:positive regulation of fibroblast growth factor production; IMP:BHF-UCL.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:RGD.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.::GO:0090362; P:positive regulation of platelet-derived growth factor production; IMP:BHF-UCL.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045987; P:positive regulation of smooth muscle contraction; IMP:RGD.::GO:0031915; P:positive regulation of synaptic plasticity; IMP:RGD.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IMP:RGD.::GO:0071636; P:positive regulation of transforming growth factor beta production; IMP:BHF-UCL.::GO:0045907; P:positive regulation of vasoconstriction; IMP:RGD.::GO:0010575; P:positive regulation vascular endothelial growth factor production; IMP:BHF-UCL.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0009750; P:response to fructose stimulus; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IMP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.::GO:0010042; P:response to manganese ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0006979; P:response to oxidative stress; IEA:InterPro.::GO:0034612; P:response to tumor necrosis factor; IEP:RGD.::GO:0033280; P:response to vitamin D; IEP:RGD.::GO:0019233; P:sensory perception of pain; IMP:RGD. | 9 | O62725 | 604 | PGH2_MUSVI Prostaglandin G/H synthase 2 OS=Mu... | 400 | 7e-25 | 114 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019371; P:cyclooxygenase pathway; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 10 | P27607 | 603 | PGH2_CHICK Prostaglandin G/H synthase 2 OS=Ga... | 414 | 3e-24 | 112 | 28 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019371; P:cyclooxygenase pathway; ISS:UniProtKB.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 11 | P70682 | 604 | PGH2_CAVPO Prostaglandin G/H synthase 2 OS=Ca... | 399 | 5e-24 | 112 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019371; P:cyclooxygenase pathway; ISS:UniProtKB.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 12 | P35354 | 604 | PGH2_HUMAN Prostaglandin G/H synthase 2 OS=Ho... | 405 | 8e-24 | 111 | 26 | 40 | GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; NAS:UniProtKB.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006928; P:cellular component movement; TAS:ProtInc.::GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.::GO:0019371; P:cyclooxygenase pathway; IDA:BHF-UCL.::GO:0090336; P:positive regulation of brown fat cell differentiation; ISS:BHF-UCL.::GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.::GO:0031622; P:positive regulation of fever generation; ISS:BHF-UCL.::GO:0090271; P:positive regulation of fibroblast growth factor production; ISS:BHF-UCL.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:BHF-UCL.::GO:0090362; P:positive regulation of platelet-derived growth factor production; ISS:BHF-UCL.::GO:0031394; P:positive regulation of prostaglandin biosynthetic process; NAS:BHF-UCL.::GO:0071636; P:positive regulation of transforming growth factor beta production; ISS:BHF-UCL.::GO:0010575; P:positive regulation vascular endothelial growth factor production; ISS:BHF-UCL.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 13 | O02768 | 604 | PGH2_RABIT Prostaglandin G/H synthase 2 OS=Or... | 405 | 2e-23 | 110 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019371; P:cyclooxygenase pathway; ISS:UniProtKB.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 14 | O19183 | 604 | PGH2_HORSE Prostaglandin G/H synthase 2 OS=Eq... | 400 | 4e-23 | 108 | 27 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019371; P:cyclooxygenase pathway; ISS:UniProtKB.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 15 | O62664 | 600 | PGH1_BOVIN Prostaglandin G/H synthase 1 OS=Bo... | 479 | 7e-23 | 108 | 26 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 16 | P79208 | 603 | PGH2_SHEEP Prostaglandin G/H synthase 2 OS=Ov... | 404 | 9e-23 | 107 | 26 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019371; P:cyclooxygenase pathway; ISS:UniProtKB.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 17 | O62698 | 604 | PGH2_BOVIN Prostaglandin G/H synthase 2 OS=Bo... | 405 | 2e-22 | 107 | 25 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019371; P:cyclooxygenase pathway; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 18 | P05979 | 600 | PGH1_SHEEP Prostaglandin G/H synthase 1 OS=Ov... | 431 | 5e-22 | 105 | 27 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 19 | P23219 | 599 | PGH1_HUMAN Prostaglandin G/H synthase 1 OS=Ho... | 431 | 3e-19 | 96.7 | 27 | 40 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005792; C:microsome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0019371; P:cyclooxygenase pathway; IDA:BHF-UCL.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 20 | O97554 | 606 | PGH1_RABIT Prostaglandin G/H synthase 1 OS=Or... | 402 | 7e-19 | 95.9 | 25 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 21 | P22437 | 602 | PGH1_MOUSE Prostaglandin G/H synthase 1 OS=Mu... | 430 | 7e-19 | 95.5 | 25 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; IEA:EC. | | | | | | | | | | GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.::GO:0008217; P:regulation of blood pressure; IMP:MGI.::GO:0042127; P:regulation of cell proliferation; IGI:MGI.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 22 | Q63921 | 602 | PGH1_RAT Prostaglandin G/H synthase 1 OS=Ratt... | 431 | 3e-17 | 90.5 | 26 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:UniProtKB.::GO:0005635; C:nuclear envelope; IDA:RGD. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0008289; F:lipid binding; IMP:RGD.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.::GO:0004666; F:prostaglandin-endoperoxide synthase activity; TAS:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0007612; P:learning; IMP:RGD.::GO:0035633; P:maintenance of blood-brain barrier; IMP:RGD.::GO:0007613; P:memory; IMP:RGD.::GO:0032811; P:negative regulation of epinephrine secretion; IMP:RGD.::GO:0010700; P:negative regulation of norepinephrine secretion; IMP:RGD.::GO:0045987; P:positive regulation of smooth muscle contraction; IMP:RGD.::GO:0045907; P:positive regulation of vasoconstriction; IMP:RGD.::GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0006979; P:response to oxidative stress; IEA:InterPro.::GO:0019233; P:sensory perception of pain; IMP:RGD. | 23 | Q7QH73 | 767 | PERC_ANOGA Chorion peroxidase OS=Anopheles ga... | 385 | 0.0000003 | 58.5 | 22 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW. | 24 | O08469 | 410 | CPXY_BACSU Cytochrome P450 OS=Bacillus subtil... | 108 | 0.0000008 | 56.6 | 35 | 51 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 25 | P0A514 | 396 | CP121_MYCTU Cytochrome P450 121 OS=Mycobacter... | 123 | 0.000002 | 55.5 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070025; F:carbon monoxide binding; IDA:MTBBASE.::GO:0009975; F:cyclase activity; IDA:MTBBASE.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:MTBBASE.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE. | 26 | P0A515 | 396 | CP121_MYCBO Cytochrome P450 121 OS=Mycobacter... | 123 | 0.000002 | 55.5 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 27 | P33006 | 428 | CPXL_PSESP Cytochrome P450-terp OS=Pseudomona... | 106 | 0.000002 | 55.5 | 30 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 28 | P82600 | 790 | PERC_AEDAE Chorion peroxidase OS=Aedes aegypt... | 397 | 0.000004 | 55.1 | 22 | 37 | GO:0005576; C:extracellular region; IC:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004601; F:peroxidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007306; P:eggshell chorion assembly; IDA:UniProtKB.::GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW. | 29 | Q06069 | 410 | CPXM_BACME Cytochrome P450(MEG) OS=Bacillus m... | 125 | 0.000005 | 53.9 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 30 | O31785 | 405 | PKSS_BACSU Polyketide biosynthesis cytochrome... | 66 | 0.000009 | 53.1 | 39 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 31 | Q00616 | 403 | NOR1_CYLTO Cytochrome P450 55A2 OS=Cylindroca... | 81 | 0.00002 | 52.4 | 35 | 54 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |
