rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q29RK2 | 1178 | PYC_BOVIN Pyruvate carboxylase, mitochondrial... | 456 | 3e-92 | 327 | 41 | 60 | GO:0005743; C:mitochondrial inner membrane; ISS:AgBase.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 32 | Q05920 | 1178 | PYC_MOUSE Pyruvate carboxylase, mitochondrial... | 456 | 5e-92 | 327 | 40 | 60 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 33 | P11498 | 1178 | PYC_HUMAN Pyruvate carboxylase, mitochondrial... | 456 | 5e-92 | 327 | 40 | 60 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0009374; F:biotin binding; TAS:ProtInc.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; TAS:Reactome. | | | | | | | | | | GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 34 | P52873 | 1178 | PYC_RAT Pyruvate carboxylase, mitochondrial O... | 456 | 7e-92 | 327 | 40 | 60 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0009374; F:biotin binding; IMP:RGD.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IDA:RGD. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IDA:RGD.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.::GO:0006107; P:oxaloacetate metabolic process; IDA:RGD.::GO:0006090; P:pyruvate metabolic process; IDA:RGD. | 35 | O52058 | 449 | ACCC_ALLVD Biotin carboxylase OS=(Chromatium ... | 456 | 2e-91 | 308 | 38 | 59 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 36 | P43873 | 448 | ACCC_HAEIN Biotin carboxylase OS=Haemophilus ... | 454 | 2e-90 | 305 | 40 | 58 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 37 | P24182 | 449 | ACCC_ECOLI Biotin carboxylase OS=Escherichia ... | 454 | 9e-90 | 303 | 40 | 57 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:EcoCyc. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IMP:EcoCyc.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IMP:EcoliWiki. | 38 | Q8X9B6 | 449 | ACCC_ECO57 Biotin carboxylase OS=Escherichia ... | 454 | 2e-89 | 302 | 39 | 57 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 39 | O17732 | 1175 | PYC1_CAEEL Pyruvate carboxylase 1 OS=Caenorha... | 67 | 0.56 | 38.1 | 36 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 40 | P46392 | 598 | BCCA_MYCLE Acetyl-/propionyl-coenzyme A carbo... | 52 | 4.2 | 35 | 38 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 41 | Q9UUE1 | 1185 | PYC_SCHPO Pyruvate carboxylase OS=Schizosacch... | 63 | 0.31 | 39.3 | 30 | 56 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; ISS:PomBase. | | | | | | | | | | GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0006094; P:gluconeogenesis; ISS:PomBase. | 42 | Q0CLK1 | 1193 | PYC_ASPTN Pyruvate carboxylase OS=Aspergillus... | 458 | 1e-85 | 308 | 39 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 43 | O93918 | 1193 | PYC_ASPTE Pyruvate carboxylase OS=Aspergillus... | 458 | 1e-85 | 307 | 39 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 44 | Q9HES8 | 1192 | PYC_ASPNG Pyruvate carboxylase OS=Aspergillus... | 458 | 2e-84 | 304 | 39 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 45 | P11154 | 1178 | PYC1_YEAST Pyruvate carboxylase 1 OS=Saccharo... | 100 | 2.9 | 35.8 | 27 | 50 | GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004736; F:pyruvate carboxylase activity; IMP:SGD. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IMP:SGD. | 46 | P32327 | 1180 | PYC2_YEAST Pyruvate carboxylase 2 OS=Saccharo... | 68 | 3.7 | 35.4 | 31 | 57 | GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IMP:SGD. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IMP:SGD. | 47 | Q8X1T3 | 1175 | PYC_PICAN Pyruvate carboxylase OS=Pichia angu... | 461 | 2e-77 | 282 | 38 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 48 | P78992 | 1189 | PYC_PICPA Pyruvate carboxylase OS=Pichia past... | 462 | 6e-76 | 278 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 49 | Q13085 | 2346 | ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo ... | 510 | 4e-59 | 228 | 31 | 50 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome. | 50 | Q5SWU9 | 2345 | ACACA_MOUSE Acetyl-CoA carboxylase 1 OS=Mus m... | 510 | 5e-59 | 228 | 31 | 50 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; IDA:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IDA:UniProtKB.::GO:0055088; P:lipid homeostasis; IMP:MGI.::GO:0044268; P:multicellular organismal protein metabolic process; IMP:MGI.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0001894; P:tissue homeostasis; IMP:MGI. | 51 | Q9TTS3 | 2346 | ACACA_BOVIN Acetyl-CoA carboxylase 1 OS=Bos t... | 510 | 8e-59 | 227 | 31 | 49 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB. | 52 | Q28559 | 2346 | ACACA_SHEEP Acetyl-CoA carboxylase 1 OS=Ovis ... | 510 | 1e-58 | 226 | 31 | 49 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB. | 53 | P11029 | 2324 | ACAC_CHICK Acetyl-CoA carboxylase OS=Gallus g... | 510 | 8e-58 | 224 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 54 | P11497 | 2345 | ACACA_RAT Acetyl-CoA carboxylase 1 OS=Rattus ... | 510 | 1e-55 | 217 | 31 | 49 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0009374; F:biotin binding; IMP:RGD.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; IDA:RGD.::GO:0006633; P:fatty acid biosynthetic process; IDA:RGD.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IMP:RGD. | 55 | O00763 | 2458 | ACACB_HUMAN Acetyl-CoA carboxylase 2 OS=Homo ... | 526 | 1e-52 | 207 | 30 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; IDA:UniProtKB.::GO:0006853; P:carnitine shuttle; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome. | 56 | Q8S6N5 | 2267 | ACC1_ORYSJ Acetyl-CoA carboxylase 1 OS=Oryza ... | 513 | 1e-50 | 200 | 30 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 57 | B9FK36 | 2327 | ACC2_ORYSJ Acetyl-CoA carboxylase 2 OS=Oryza ... | 513 | 2e-50 | 200 | 29 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 58 | Q38970 | 2254 | ACC1_ARATH Acetyl-CoA carboxylase 1 OS=Arabid... | 513 | 4e-50 | 199 | 29 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030497; P:fatty acid elongation; IMP:TAIR.::GO:0010072; P:primary shoot apical meristem specification; IMP:TAIR.::GO:0009735; P:response to cytokinin stimulus; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR. | 59 | A6ZMR9 | 2273 | HFA1_YEAS7 Acetyl-CoA carboxylase, mitochondr... | 509 | 2e-49 | 197 | 29 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 60 | P32874 | 2273 | HFA1_YEAST Acetyl-CoA carboxylase, mitochondr... | 509 | 2e-49 | 196 | 29 | 47 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IGI:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IGI:SGD. | 61 | F4I1L3 | 2355 | ACC2_ARATH Acetyl-CoA carboxylase 2 OS=Arabid... | 514 | 2e-49 | 196 | 29 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. |