Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR180W
Length:
347
Number of sequences:
5887
Description:
YPR180W AOS1 SGDID:S000006384, Chr XVI from 895961-897004, Genome Release 64-1-1, Verified ORF, "Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06624    347   RHC31_YEAST DNA damage tolerance protein RHC3...3470     708     100     100GO:0031510; C:SUMO activating enzyme complex; IPI:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019948; F:SUMO activating enzyme activity; IDA:SGD.
GO:0016925; P:protein sumoylation; IDA:SGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
2Q5NVN7    346   SAE1_PONAB SUMO-activating enzyme subunit 1 O...3412e-54     187     34     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
3Q9UBE0    346   SAE1_HUMAN SUMO-activating enzyme subunit 1 O...3412e-54     187     34     55GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043008; F:ATP-dependent protein binding; IDA:UniProtKB.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0004839; F:ubiquitin activating enzyme activity; TAS:UniProtKB.
GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0016567; P:protein ubiquitination; TAS:UniProtKB.
4Q6AXQ0    349   SAE1_RAT SUMO-activating enzyme subunit 1 OS=...3341e-51     180     33     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
5Q9R1T2    350   SAE1_MOUSE SUMO-activating enzyme subunit 1 O...3345e-50     176     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
6A2VE14    346   SAE1_BOVIN SUMO-activating enzyme subunit 1 O...3411e-49     175     33     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
7Q8JGT5    344   SAE1_XENLA SUMO-activating enzyme subunit 1 O...3426e-48     170     31     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
8Q28DS0    347   SAE1_XENTR SUMO-activating enzyme subunit 1 O...3401e-46     167     30     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
9P79064    307   RAD31_SCHPO DNA damage tolerance protein rad3...3433e-46     165     31     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0031510; C:SUMO activating enzyme complex; TAS:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019948; F:SUMO activating enzyme activity; ISS:PomBase.
GO:0016925; P:protein sumoylation; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.::GO:0006974; P:response to DNA damage stimulus; IMP:PomBase.
10Q6IQS6    348   SAE1_DANRE SUMO-activating enzyme subunit 1 O...3391e-43     159     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
11Q54WI4    330   SAE1_DICDI SUMO-activating enzyme subunit 1 O...3387e-35     135     28     48GO:0031510; C:SUMO activating enzyme complex; ISS:dictyBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019948; F:SUMO activating enzyme activity; ISS:dictyBase.
GO:0016925; P:protein sumoylation; ISS:dictyBase.
12Q17820    343   SAE1_CAEEL SUMO-activating enzyme subunit aos...3423e-29     119     25     47
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040019; P:positive regulation of embryonic development; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase.
13P0DI13    320   SA1B2_ARATH SUMO-activating enzyme subunit 1B...3469e-29     117     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
14P0DI12    320   SA1B1_ARATH SUMO-activating enzyme subunit 1B...3469e-29     117     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
15Q8VY78    322   SAE1A_ARATH SUMO-activating enzyme subunit 1A...3463e-28     116     25     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
16Q9SJT1    700   SAE2_ARATH SUMO-activating enzyme subunit 2 O...1410.000000000001     72.4     28     50GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; IDA:TAIR.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0016925; P:protein sumoylation; IDA:TAIR.
17B0W377    438   MOCS3_CULQU Adenylyltransferase and sulfurtra...1540.00000000001     68.9     31     51GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
18O42939    628   UBA2_SCHPO Ubiquitin-activating enzyme E1-lik...1680.00000000002     68.6     27     47GO:0031510; C:SUMO activating enzyme complex; TAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:PomBase.
GO:0016925; P:protein sumoylation; IGI:PomBase.
19Q0CFD4    484   UBA4_ASPTN Adenylyltransferase and sulfurtran...1240.00000000003     67.8     30     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
20Q9NAN1    582   SAE2_CAEEL SUMO-activating enzyme subunit uba...1330.00000000005     67.4     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; IDA:WormBase.
GO:0009952; P:anterior/posterior pattern specification; IGI:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
21Q2TWN3    463   UBA4_ASPOR Adenylyltransferase and sulfurtran...1030.00000000005     67.4     31     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
22Q756K6    443   UBA4_ASHGO Adenylyltransferase and sulfurtran...1240.00000000005     67     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
23A5DMB6    424   UBA4_PICGU Adenylyltransferase and sulfurtran...1590.00000000007     66.6     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
24A2R3H4    482   UBA4_ASPNC Adenylyltransferase and sulfurtran...1230.0000000002     65.9     29     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
25Q54L40    661   SAE2_DICDI SUMO-activating enzyme subunit 2 O...1510.0000000002     65.9     26     50GO:0031510; C:SUMO activating enzyme complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:dictyBase.
GO:0016925; P:protein sumoylation; ISS:dictyBase.
26A1CAZ7    492   UBA4_ASPCL Adenylyltransferase and sulfurtran...1230.0000000002     65.5     28     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
27Q7D5X9    392   MOEZ_MYCTU Probable adenylyltransferase/sulfu...1230.0000000003     64.7     29     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.::GO:0008146; F:sulfotransferase activity; IDA:MTBBASE.
GO:0042783; P:active evasion of host immune response; IMP:MTBBASE.::GO:0006535; P:cysteine biosynthetic process from serine; TAS:Reactome.
28B4HYP0    453   MOCS3_DROSE Adenylyltransferase and sulfurtra...1520.0000000004     64.3     25     49GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
29Q6FR35    433   UBA4_CANGA Adenylyltransferase and sulfurtran...1260.0000000007     63.5     29     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
30A4RPM5    490   UBA4_MAGO7 Adenylyltransferase and sulfurtran...1230.0000000009     63.5     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0043581; P:mycelium development; IEP:PAMGO_MGG.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
31Q09810    401   UBA4_SCHPO Adenylyltransferase and sulfurtran...1020.000000001     62.8     33     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:PomBase.::GO:0042292; F:URM1 activating enzyme activity; ISS:PomBase.
GO:0034599; P:cellular response to oxidative stress; ISS:PomBase.::GO:0032447; P:protein urmylation; IC:PomBase.::GO:0002143; P:tRNA wobble position uridine thiolation; ISS:PomBase.
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