Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR180W
Length:
347
Number of sequences:
5887
Description:
YPR180W AOS1 SGDID:S000006384, Chr XVI from 895961-897004, Genome Release 64-1-1, Verified ORF, "Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q09810    401   UBA4_SCHPO Adenylyltransferase and sulfurtran...1020.000000001     62.8     33     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:PomBase.::GO:0042292; F:URM1 activating enzyme activity; ISS:PomBase.
GO:0034599; P:cellular response to oxidative stress; ISS:PomBase.::GO:0032447; P:protein urmylation; IC:PomBase.::GO:0002143; P:tRNA wobble position uridine thiolation; ISS:PomBase.
32O59954    482   UBA4_EMENI Adenylyltransferase and sulfurtran...1230.000000002     62.4     28     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
33B0Y0P7    493   UBA4_ASPFC Adenylyltransferase and sulfurtran...1230.000000003     62     28     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
34A5DSR2    455   UBA4_LODEL Adenylyltransferase and sulfurtran...1260.000000003     61.6     30     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
35Q9Z1F9    638   SAE2_MOUSE SUMO-activating enzyme subunit 2 O...1310.000000003     62     28     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:MGI.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
36P12282    249   MOEB_ECOLI Molybdopterin-synthase adenylyltra...1030.000000003     60.5     30     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
37Q9VLJ8    453   MOCS3_DROME Adenylyltransferase and sulfurtra...1520.000000004     61.2     25     49GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
38Q7ZVX6    462   UBA3_DANRE NEDD8-activating enzyme E1 catalyt...980.000000004     61.2     30     54
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0045116; P:protein neddylation; IEA:InterPro.
39P31254    1058   UBA1Y_MOUSE Ubiquitin-like modifier-activatin...1850.000000005     61.2     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
40Q4WV19    493   UBA4_ASPFU Adenylyltransferase and sulfurtran...1230.000000005     60.8     28     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
41P45211    243   MOEB_HAEIN Molybdopterin-synthase adenylyltra...1470.000000008     58.9     25     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
42Q7PY41    441   MOCS3_ANOGA Adenylyltransferase and sulfurtra...1540.00000002     59.3     29     47GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
43Q9V6U8    450   UBA3_DROME NEDD8-activating enzyme E1 catalyt...950.00000002     59.3     32     49GO:0043234; C:protein complex; IPI:FlyBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0045116; P:protein neddylation; IDA:FlyBase.
44Q6BHZ2    448   UBA4_DEBHA Adenylyltransferase and sulfurtran...1260.00000002     59.3     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
45P52488    636   UBA2_YEAST Ubiquitin-activating enzyme E1-lik...1450.00000002     59.3     25     48GO:0031510; C:SUMO activating enzyme complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; IPI:SGD.
GO:0016925; P:protein sumoylation; IDA:SGD.
46Q29PG5    451   MOC32_DROPS Adenylyltransferase and sulfurtra...1520.00000002     58.9     24     48GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
47Q29504    1058   UBA1_RABIT Ubiquitin-like modifier-activating...1980.00000003     58.9     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
48B4GKQ3    451   MOCS3_DROPE Adenylyltransferase and sulfurtra...1520.00000003     58.9     24     48GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
49Q54QG9    442   UBA3_DICDI NEDD8-activating enzyme E1 catalyt...1080.00000003     58.5     31     53
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; ISS:dictyBase.
GO:0045116; P:protein neddylation; ISS:dictyBase.
50B5DS72    451   MOC31_DROPS Adenylyltransferase and sulfurtra...1520.00000003     58.5     24     48GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
51P52495    1021   UBA1_CANAW Ubiquitin-activating enzyme E1 1 O...1540.00000004     58.9     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
52O44510    402   MOCS3_CAEEL Adenylyltransferase and sulfurtra...1570.00000004     58.2     25     49GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
53A8WRE3    402   MOCS3_CAEBR Adenylyltransferase and sulfurtra...1540.00000004     58.2     25     48GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
54Q9UBT2    640   SAE2_HUMAN SUMO-activating enzyme subunit 2 O...1310.00000004     58.5     27     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0019948; F:SUMO activating enzyme activity; IDA:UniProtKB.
GO:0016925; P:protein sumoylation; IDA:UniProtKB.
55B4NXF7    453   MOCS3_DROYA Adenylyltransferase and sulfurtra...1520.00000004     58.2     24     48GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
56Q7SXG4    650   SAE2_DANRE SUMO-activating enzyme subunit 2 O...1370.00000005     58.2     26     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
57A5GFZ6    455   MOCS3_PIG Adenylyltransferase and sulfurtrans...1730.00000006     57.8     25     45GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016779; F:nucleotidyltransferase activity; ISS:UniProtKB.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.::GO:0042292; F:URM1 activating enzyme activity; ISS:UniProtKB.
GO:0018192; P:enzyme active site formation via L-cysteine persulfide; ISS:UniProtKB.::GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0034227; P:tRNA thio-modification; ISS:UniProtKB.::GO:0002098; P:tRNA wobble uridine modification; ISS:UniProtKB.
58A7THV5    436   UBA4_VANPO Adenylyltransferase and sulfurtran...1860.00000006     57.8     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
59A1A4L8    455   MOCS3_BOVIN Adenylyltransferase and sulfurtra...1230.00000006     57.8     28     49GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016779; F:nucleotidyltransferase activity; ISS:UniProtKB.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.::GO:0042292; F:URM1 activating enzyme activity; ISS:UniProtKB.
GO:0018192; P:enzyme active site formation via L-cysteine persulfide; ISS:UniProtKB.::GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0034227; P:tRNA thio-modification; ISS:UniProtKB.::GO:0002098; P:tRNA wobble uridine modification; ISS:UniProtKB.
60P92974    1077   UBE12_ARATH Ubiquitin-activating enzyme E1 2 ...3180.00000007     57.8     23     38GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
61Q6B908    355   MOEB_GRATL Probable molybdopterin-synthase ad...1270.00000007     57     28     49GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
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