UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPR178W

Length:

465

Number of sequences:

5887

Description:

YPR178W PRP4 SGDID:S000006382, Chr XVI from 892332-893729, Genome Release 64-1-1, Verified ORF, "Splicing factor, component of the U4/U6-U5 snRNP complex"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P20053	465	PRP4_YEAST U4/U6 small nuclear ribonucleoprot...	465	0	956	100	100	GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.
2	Q6PH57	340	GBB1_DANRE Guanine nucleotide-binding protein...	344	1e-28	119	27	46
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
3	P17343	340	GBB1_CAEEL Guanine nucleotide-binding protein...	339	1e-28	119	29	46
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040013; P:negative regulation of locomotion; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.
4	Q61ZF6	340	GBB1_CAEBR Guanine nucleotide-binding protein...	339	1e-28	119	29	46
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
5	Q9HAV0	340	GBB4_HUMAN Guanine nucleotide-binding protein...	344	3e-28	117	28	46	GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
6	P54313	340	GBB2_RAT Guanine nucleotide-binding protein G...	344	7e-28	117	28	45	GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.
									GO:0005246; F:calcium channel regulator activity; IMP:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
7	P62880	340	GBB2_MOUSE Guanine nucleotide-binding protein...	344	7e-28	117	28	45	GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:MGI.
8	P62879	340	GBB2_HUMAN Guanine nucleotide-binding protein...	344	7e-28	117	28	45	GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome.
9	P11017	340	GBB2_BOVIN Guanine nucleotide-binding protein...	344	7e-28	117	28	45	GO:0005834; C:heterotrimeric G-protein complex; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
									GO:0003924; F:GTPase activity; IDA:MGI.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
10	P79959	340	GBB1_XENLA Guanine nucleotide-binding protein...	344	3e-26	112	28	46
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
11	P26308	340	GBB1_DROME Guanine nucleotide-binding protein...	345	2e-25	110	26	44	GO:0005875; C:microtubule associated complex; IDA:FlyBase.
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0045176; P:apical protein localization; TAS:FlyBase.::GO:0055059; P:asymmetric neuroblast division; IMP:FlyBase.
12	O35353	340	GBB4_RAT Guanine nucleotide-binding protein s...	344	5e-25	108	28	46
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
13	P29387	340	GBB4_MOUSE Guanine nucleotide-binding protein...	344	7e-25	108	28	46
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:MGI.
14	P16520	340	GBB3_HUMAN Guanine nucleotide-binding protein...	346	9e-25	107	25	47	GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0008217; P:regulation of blood pressure; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome.
15	P52287	340	GBB3_RAT Guanine nucleotide-binding protein G...	346	2e-24	107	25	46
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
16	Q61011	340	GBB3_MOUSE Guanine nucleotide-binding protein...	343	1e-23	105	24	46	GO:0005834; C:heterotrimeric G-protein complex; TAS:MGI.
									GO:0003924; F:GTPase activity; TAS:MGI.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:MGI.
17	Q08E38	504	PRP19_BOVIN Pre-mRNA-processing factor 19 OS=...	305	1e-23	106	25	43	GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
18	Q9JMJ4	504	PRP19_RAT Pre-mRNA-processing factor 19 OS=Ra...	305	1e-23	106	25	42	GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
19	Q99KP6	504	PRP19_MOUSE Pre-mRNA-processing factor 19 OS=...	305	1e-23	106	25	42	GO:0005811; C:lipid particle; IDA:MGI.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0001833; P:inner cell mass cell proliferation; IMP:MGI.::GO:0008610; P:lipid biosynthetic process; IDA:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.::GO:0048711; P:positive regulation of astrocyte differentiation; IDA:MGI.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; IMP:MGI.
20	P79147	340	GBB3_CANFA Guanine nucleotide-binding protein...	343	2e-23	104	24	46	GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
21	Q9UMS4	504	PRP19_HUMAN Pre-mRNA-processing factor 19 OS=...	305	2e-23	105	25	42	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:BHF-UCL.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:BHF-UCL.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:MGI.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0000245; P:spliceosomal complex assembly; IMP:BHF-UCL.
22	Q5ZMA2	505	PRP19_CHICK Pre-mRNA-processing factor 19 OS=...	289	9e-23	104	26	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
23	Q9D7H2	328	WDR5B_MOUSE WD repeat-containing protein 5B O...	340	4e-22	100	27	46
24	Q10051	492	PRP19_CAEEL Pre-mRNA-processing factor 19 hom...	379	3e-21	99.8	25	45	GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
									GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
25	Q4V8C4	328	WDR5B_RAT WD repeat-containing protein 5B OS=...	316	3e-21	97.4	27	46
26	O74319	642	TAF73_SCHPO Transcription initiation factor T...	326	9e-21	99	23	40	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005669; C:transcription factor TFIID complex; TAS:PomBase.
									GO:0000991; F:core RNA polymerase II binding transcription factor activity; IC:PomBase.
									GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IGI:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:PomBase.
27	P49695	742	PKWA_THECU Probable serine/threonine-protein ...	251	3e-20	97.4	29	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
28	Q8YTC2	1258	Y2800_NOSS1 Uncharacterized WD repeat-contain...	221	3e-20	97.8	29	48
									GO:0043531; F:ADP binding; IEA:InterPro.
									GO:0006952; P:defense response; IEA:InterPro.
29	A8X8C6	368	TG125_CAEBR WD repeat-containing protein tag-...	260	3e-20	95.1	27	43
30	Q8YV57	1683	Y2124_NOSS1 Uncharacterized WD repeat-contain...	207	8e-20	96.7	32	48
									GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:InterPro.
31	P93107	606	PF20_CHLRE Flagellar WD repeat-containing pro...	251	1e-19	95.5	25	45	GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.

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