Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR173C
Length:
437
Number of sequences:
5887
Description:
YPR173C VPS4 SGDID:S000006377, Chr XVI from 887837-886524, Genome Release 64-1-1, reverse complement, Verified ORF, "AAA-ATPase involved in multivesicular body (MVB) protein sorting, ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P52917    437   VPS4_YEAST Vacuolar protein sorting-associate...4370     895     100     100GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0042803; F:protein homodimerization activity; IDA:SGD.
GO:0070676; P:intralumenal vesicle formation; IMP:SGD.::GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IMP:SGD.::GO:0051260; P:protein homooligomerization; IDA:SGD.::GO:0045053; P:protein retention in Golgi apparatus; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IMP:SGD.
2Q09803    432   VPS4_SCHPO Suppressor protein of bem1/bed5 do...4360     539     62     76GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0045053; P:protein retention in Golgi apparatus; ISS:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
3O75351    444   VPS4B_HUMAN Vacuolar protein sorting-associat...4490     528     60     74GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005774; C:vacuolar membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IMP:UniProtKB.::GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0032510; P:endosome to lysosome transport via multivesicular body sorting pathway; IMP:UniProtKB.::GO:0032367; P:intracellular cholesterol transport; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0033993; P:response to lipid; IDA:UniProtKB.
4Q0VD48    444   VPS4B_BOVIN Vacuolar protein sorting-associat...4520     528     60     73GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
5Q5R658    444   VPS4B_PONAB Vacuolar protein sorting-associat...4490     527     60     74GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
6Q9UN37    437   VPS4A_HUMAN Vacuolar protein sorting-associat...4440     521     59     74GO:0005829; C:cytosol; TAS:Reactome.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0000910; P:cytokinesis; IDA:UniProtKB.::GO:0016197; P:endosome transport; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
7Q793F9    437   VPS4A_RAT Vacuolar protein sorting-associated...4440     520     59     74GO:0005769; C:early endosome; IDA:RGD.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IPI:RGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016197; P:endosome transport; IC:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
8Q8VEJ9    437   VPS4A_MOUSE Vacuolar protein sorting-associat...4440     520     59     74GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
9P46467    444   VPS4B_MOUSE Vacuolar protein sorting-associat...4497e-178     512     61     73GO:0005829; C:cytosol; IDA:MGI.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007032; P:endosome organization; IMP:MGI.::GO:0006813; P:potassium ion transport; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
10Q54PT2    444   VPS4_DICDI Vacuolar protein sorting-associate...4462e-175     505     57     73GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0016197; P:endosome transport; ISS:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
11Q5RII9    485   KTNA1_DANRE Katanin p60 ATPase-containing sub...3352e-82     268     47     61GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0048676; P:axon extension involved in development; IMP:ZFIN.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0031122; P:cytoplasmic microtubule organization; IMP:ZFIN.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
12Q9SEX2    523   KTNA1_ARATH Katanin p60 ATPase-containing sub...3674e-82     268     41     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043622; P:cortical microtubule organization; IMP:TAIR.::GO:0009825; P:multidimensional cell growth; IMP:TAIR.::GO:0009832; P:plant-type cell wall biogenesis; IMP:TAIR.::GO:0010091; P:trichome branching; IMP:TAIR.
13Q5U3S1    488   KATL1_DANRE Katanin p60 ATPase-containing sub...3743e-81     265     43     57GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
14B5X3X5    486   KTNA1_SALSA Katanin p60 ATPase-containing sub...3361e-80     263     46     60GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
15O61577    516   KTNA1_STRPU Katanin p60 ATPase-containing sub...3572e-80     263     44     59GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
16A0JMA9    542   KATL2_XENTR Katanin p60 ATPase-containing sub...2555e-80     263     50     69GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
17Q1HGK7    492   KTNA1_CHICK Katanin p60 ATPase-containing sub...3363e-79     259     46     61GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
18P40328    754   TBP6_YEAST Probable 26S protease subunit YTA6...3275e-79     266     44     60GO:0005938; C:cell cortex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
19Q9PUL2    486   KTNA1_XENLA Katanin p60 ATPase-containing sub...3847e-79     259     41     56GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
20Q0IIR9    492   KTNA1_XENTR Katanin p60 ATPase-containing sub...3361e-78     258     44     60GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
21Q4R407    491   KTNA1_MACFA Katanin p60 ATPase-containing sub...3364e-78     257     45     61GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
22O75449    491   KTNA1_HUMAN Katanin p60 ATPase-containing sub...3366e-78     256     45     61GO:0005813; C:centrosome; IDA:HPA.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051329; P:interphase of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
23B3EX35    490   KATL1_SORAR Katanin p60 ATPase-containing sub...4031e-77     255     40     57GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
24B7NZ88    490   KATL1_RABIT Katanin p60 ATPase-containing sub...3856e-77     254     42     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
25B4USW8    490   KATL1_OTOGA Katanin p60 ATPase-containing sub...4037e-77     253     40     57GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
26Q9D3R6    539   KATL2_MOUSE Katanin p60 ATPase-containing sub...3271e-76     254     43     60GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
27Q6E0V2    491   KTNA1_RAT Katanin p60 ATPase-containing subun...3392e-76     253     45     60GO:0030424; C:axon; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005634; C:nucleus; TAS:RGD.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; TAS:RGD.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051013; P:microtubule severing; IDA:RGD.::GO:0007067; P:mitosis; TAS:RGD.::GO:0010977; P:negative regulation of neuron projection development; IDA:RGD.::GO:0008104; P:protein localization; TAS:RGD.
28Q9BW62    490   KATL1_HUMAN Katanin p60 ATPase-containing sub...3864e-76     251     41     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
29A9RA82    490   KATL1_PAPAN Katanin p60 ATPase-containing sub...3869e-76     251     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
30Q8K0T4    488   KATL1_MOUSE Katanin p60 ATPase-containing sub...3383e-75     249     44     61GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
31Q5XIK7    488   KATL1_RAT Katanin p60 ATPase-containing subun...3863e-75     249     41     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
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