UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPR168W

Length:

157

Number of sequences:

5887

Description:

YPR168W NUT2 SGDID:S000006372, Chr XVI from 878076-878549, Genome Release 64-1-1, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for transcriptional activation and has a role in basal transcription"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q06213	157	MED10_YEAST Mediator of RNA polymerase II tra...	157	9e-112	321	100	100	GO:0070847; C:core mediator complex; IDA:SGD.::GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
									GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
2	Q6FQ75	199	MED10_CANGA Mediator of RNA polymerase II tra...	140	3e-73	224	72	89	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
3	Q6CVN3	161	MED10_KLULA Mediator of RNA polymerase II tra...	143	4e-65	202	65	85	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
4	Q758M1	151	MED10_ASHGO Mediator of RNA polymerase II tra...	139	5e-61	192	65	83	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
5	Q5A3K2	170	MED10_CANAL Mediator of RNA polymerase II tra...	145	1e-38	135	46	70	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
6	Q6BWK1	147	MED10_DEBHA Mediator of RNA polymerase II tra...	135	2e-32	118	44	62	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
7	A3LPQ8	146	MED10_PICST Mediator of RNA polymerase II tra...	135	4e-31	115	43	65	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
8	Q2H8S0	167	MED10_CHAGB Mediator of RNA polymerase II tra...	138	2e-21	90.1	35	57	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
9	Q7RXK7	253	MED10_NEUCR Mediator of RNA polymerase II tra...	92	4e-20	87.8	42	63	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
10	Q1E0Q7	242	MED10_COCIM Mediator of RNA polymerase II tra...	139	2e-18	83.6	33	55	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
11	Q5B5I6	165	MED10_EMENI Mediator of RNA polymerase II tra...	151	3e-16	75.9	29	52	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
12	Q6C5P0	143	MED10_YARLI Mediator of RNA polymerase II tra...	124	7e-16	74.7	36	56	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
13	Q4WJH6	159	MED10_ASPFU Mediator of RNA polymerase II tra...	149	0.000000000000006	72.4	29	48	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
14	Q0U8U9	133	MED10_PHANO Mediator of RNA polymerase II tra...	123	0.00000000000001	71.2	35	55	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
15	Q0CTF3	155	MED10_ASPTN Mediator of RNA polymerase II tra...	146	0.00000000000001	71.6	27	51	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
16	A1CR70	167	MED10_ASPCL Mediator of RNA polymerase II tra...	81	0.00000000000001	71.2	40	60	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
17	A1D434	167	MED10_NEOFI Mediator of RNA polymerase II tra...	155	0.0000000000001	68.9	27	47	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
18	P87310	138	MED10_SCHPO Mediator of RNA polymerase II tra...	140	0.0000000000001	68.6	27	53	GO:0005829; C:cytosol; IDA:PomBase.::GO:0016592; C:mediator complex; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; TAS:PomBase.
19	Q9CXU0	135	MED10_MOUSE Mediator of RNA polymerase II tra...	130	0.0000000001	59.7	29	50	GO:0016592; C:mediator complex; IDA:MGI.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
									GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
20	Q5R6P5	135	MED10_PONAB Mediator of RNA polymerase II tra...	130	0.0000000002	59.3	29	50
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
21	Q9BTT4	135	MED10_HUMAN Mediator of RNA polymerase II tra...	130	0.0000000002	59.3	29	50
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
									GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
22	Q3ZCF2	135	MED10_BOVIN Mediator of RNA polymerase II tra...	130	0.0000000002	59.3	29	50
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
23	Q6IP67	135	MED10_XENLA Mediator of RNA polymerase II tra...	125	0.0000000002	59.3	28	50	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
24	Q6DJ25	135	MED10_XENTR Mediator of RNA polymerase II tra...	130	0.0000000002	58.9	30	49	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
25	Q4R6W4	135	MED10_MACFA Mediator of RNA polymerase II tra...	130	0.0000000003	58.5	29	49	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
26	Q0VIA1	134	MED10_DANRE Mediator of RNA polymerase II tra...	130	0.0000000003	58.5	30	50	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
									GO:0007507; P:heart development; IMP:ZFIN.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
27	Q4PDA7	197	MED10_USTMA Mediator of RNA polymerase II tra...	114	0.00000006	52.8	30	48	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
28	Q7Q5R5	130	MED10_ANOGA Mediator of RNA polymerase II tra...	58	0.0000006	48.9	33	64	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
29	Q16G71	130	MED10_AEDAE Mediator of RNA polymerase II tra...	58	0.000001	48.1	33	64	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
30	Q9GYU7	133	MED10_DROME Mediator of RNA polymerase II tra...	126	0.000008	45.8	26	48	GO:0016592; C:mediator complex; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IMP:UniProtKB.
31	Q61Z20	173	MED10_CAEBR Mediator of RNA polymerase II tra...	93	0.00002	45.4	26	52	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.

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