Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR154W
Length:
215
Number of sequences:
5887
Description:
YPR154W PIN3 SGDID:S000006358, Chr XVI from 834565-835212, Genome Release 64-1-1, Verified ORF, "Protein that induces appearance of [PIN+] prion when overproduced"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q17QN6    466   EM55_BOVIN 55 kDa erythrocyte membrane protei...1100.47     35     25     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
362Q14847    261   LASP1_HUMAN LIM and SH3 domain protein 1 OS=H...680.47     34.7     25     50GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.
GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
363P57075    661   UBS3A_HUMAN Ubiquitin-associated and SH3 doma...900.5     35     27     44GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
364B3DLB3    433   ANM2_XENTR Protein arginine N-methyltransfera...400.5     34.7     40     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB.
GO:0048588; P:developmental cell growth; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.
365Q9P7E8    857   APP1_SCHPO Protein app1 OS=Schizosaccharomyce...640.51     35     31     63GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.
GO:0003779; F:actin binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IC:PomBase.
366Q9V9J3    517   SRC42_DROME Tyrosine-protein kinase Src42A OS...840.51     34.7     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase.
367P34416    335   LASP1_CAEEL LIM and SH3 domain protein F42H10...550.54     34.7     33     51
GO:0008270; F:zinc ion binding; IEA:InterPro.
368Q6DTM3    1047   AHI1_RAT Jouberin OS=Rattus norvegicus (Rat)....780.54     34.7     29     50GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0036038; C:TCTN-B9D complex; ISS:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0035844; P:cloaca development; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0071599; P:otic vesicle development; ISS:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; ISS:UniProtKB.::GO:0050795; P:regulation of behavior; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0065001; P:specification of axis polarity; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
369A8MVU1    366   NCF1C_HUMAN Putative neutrophil cytosol facto...580.56     34.7     24     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
370O76041    1014   NEBL_HUMAN Nebulette OS=Homo sapiens (Human)....570.58     34.7     28     54GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0031005; F:filamin binding; IPI:UniProtKB.::GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.::GO:0005523; F:tropomyosin binding; IPI:UniProtKB.
GO:0071691; P:cardiac muscle thin filament assembly; IMP:UniProtKB.
371P38041    980   BOB1_YEAST Protein BOB1 OS=Saccharomyces cere...550.61     34.7     33     60GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD.
372A6NI72    391   NCF1B_HUMAN Putative neutrophil cytosol facto...580.62     34.3     24     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
373P08103    524   HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus ...520.63     34.7     35     56GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0050830; P:defense response to Gram-positive bacterium; IGI:MGI.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IMP:MGI.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB.
374P14598    390   NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom...580.63     34.3     24     50GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL.
375Q6YKA8    211   DRK_DROSI Protein E(sev)2B OS=Drosophila simu...530.64     33.9     30     55GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
376Q08012    211   DRK_DROME Protein enhancer of sevenless 2B OS...530.64     33.9     30     55GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase.
377Q8N157    1196   AHI1_HUMAN Jouberin OS=Homo sapiens (Human). ...660.64     34.7     32     53GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0035844; P:cloaca development; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0071599; P:otic vesicle development; ISS:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; ISS:UniProtKB.::GO:0050795; P:regulation of behavior; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0065001; P:specification of axis polarity; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
378A1IGU4    676   ARH37_MOUSE Rho guanine nucleotide exchange f...740.64     34.7     32     49GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
379Q07839    416   EG13_ECHGR Antigen EG13 OS=Echinococcus granu...500.68     34.3     36     50
380Q8VCM2    349   NOXO1_MOUSE NADPH oxidase organizer 1 OS=Mus ...510.69     34.3     31     53
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IDA:MGI.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0022617; P:extracellular matrix disassembly; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:MGI.
381Q8VCZ6    750   SGSM3_MOUSE Small G protein signaling modulat...500.69     34.3     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005921; C:gap junction; IDA:UniProtKB.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
382Q07840    426   EM13_ECHMU Antigen EM13 OS=Echinococcus multi...500.7     34.3     36     50
383Q5U2Y3    576   MPP7_RAT MAGUK p55 subfamily member 7 OS=Ratt...610.7     34.3     25     52GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
384Q1LYG0    1119   SPD2A_DANRE SH3 and PX domain-containing prot...590.7     34.7     27     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB.
385Q6P6R7    749   SGSM3_RAT Small G protein signaling modulator...500.71     34.3     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
386Q62077    1302   PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho...700.72     34.7     27     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
387B5DFQ4    759   RHG26_XENTR Rho GTPase-activating protein 26 ...510.73     34.3     33     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
388O88954    585   MPP3_RAT MAGUK p55 subfamily member 3 OS=Ratt...1440.74     34.3     25     43
GO:0030165; F:PDZ domain binding; IPI:RGD.
389Q14511    834   CASL_HUMAN Enhancer of filamentation 1 OS=Hom...530.77     34.3     34     53GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051017; P:actin filament bundle assembly; NAS:UniProtKB.::GO:0007155; P:cell adhesion; NAS:ProtInc.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
390P10686    1290   PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosp...700.79     34.3     27     53GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0006816; P:calcium ion transport; IMP:RGD.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IMP:RGD.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:RGD.::GO:0009306; P:protein secretion; IMP:RGD.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.
391Q9TU19    565   NPHP1_CANFA Nephrocystin-1 OS=Canis familiari...590.8     34.3     36     53GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
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