UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPR152C

Length:

465

Number of sequences:

5887

Description:

YPR152C URN1 SGDID:S000006356, Chr XVI from 833458-832061, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative protein of unknown function containing WW and FF domains; overexpression causes accumulation of cells in G1 phase"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q8IWW6	846	RHG12_HUMAN Rho GTPase-activating protein 12 ...	30	1.4	35	40	67	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
32	O14176	695	PRP40_SCHPO Pre-mRNA-processing protein prp40...	280	1.5	35	21	39	GO:0000243; C:commitment complex; ISS:PomBase.::GO:0005685; C:U1 snRNP; IDA:PomBase.
									GO:0003723; F:RNA binding; ISS:PomBase.
									GO:0000395; P:nuclear mRNA 5'-splice site recognition; IC:PomBase.
33	Q01206	2410	POL1_BAYMJ Genome polyprotein 1 OS=Barley yel...	131	1.5	35.4	24	47	GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:InterPro.::GO:0018144; P:RNA-protein covalent cross-linking; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.
34	Q8C0D4	838	RHG12_MOUSE Rho GTPase-activating protein 12 ...	30	1.6	35	40	67	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0007165; P:signal transduction; IEA:InterPro.
35	P46937	504	YAP1_HUMAN Yorkie homolog OS=Homo sapiens (Hu...	78	2.3	34.3	27	44	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
									GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0071480; P:cellular response to gamma radiation; IDA:UniProtKB.::GO:0060242; P:contact inhibition; IDA:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
36	P34600	724	YO61_CAEEL WW domain-containing protein ZK109...	78	4.6	33.5	26	42
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
37	Q9H0M0	922	WWP1_HUMAN NEDD4-like E3 ubiquitin-protein li...	26	4.8	33.5	42	69	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; NAS:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.
									GO:0007417; P:central nervous system development; NAS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007165; P:signal transduction; NAS:UniProtKB.::GO:0046718; P:viral entry into host cell; TAS:UniProtKB.
38	Q8BZZ3	918	WWP1_MOUSE NEDD4-like E3 ubiquitin-protein li...	26	4.9	33.5	42	69	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
									GO:0030324; P:lung development; TAS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0030217; P:T cell differentiation; TAS:UniProtKB.
39	Q5HZF2	374	WBP4_RAT WW domain-binding protein 4 OS=Rattu...	104	5.3	33.1	29	43	GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:UniProtKB.
40	Q9YJW3	2410	POL1_BAYMY Genome polyprotein 1 OS=Barley yel...	131	6.4	33.1	23	46	GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:InterPro.::GO:0018144; P:RNA-protein covalent cross-linking; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.
41	O15428	100	PINL_HUMAN Putative PIN1-like protein OS=Homo...	28	6.6	30.8	39	68
42	Q9BE31	847	RHG12_MACFA Rho GTPase-activating protein 12 ...	30	6.6	33.1	37	67	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0007165; P:signal transduction; IEA:InterPro.
43	Q6ZUM4	889	RHG27_HUMAN Rho GTPase-activating protein 27 ...	67	6.7	33.1	28	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:HGNC.::GO:0017124; F:SH3 domain binding; ISS:HGNC.
									GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:HGNC.::GO:0006898; P:receptor-mediated endocytosis; ISS:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro.
44	Q61048	376	WBP4_MOUSE WW domain-binding protein 4 OS=Mus...	81	7.9	32.3	31	44	GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IDA:MGI.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:UniProtKB.
45	Q45VV3	418	YORKI_DROME Protein yorkie OS=Drosophila mela...	26	8.8	32.3	46	65	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:FlyBase.
									GO:0035212; P:cell competition in a multicellular organism; IMP:FlyBase.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:FlyBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46	P33203	583	PRP40_YEAST Pre-mRNA-processing protein PRP40...	30	8.9	32.7	43	60	GO:0005685; C:U1 snRNP; IDA:SGD.::GO:0071004; C:U2-type prespliceosome; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IDA:SGD.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IDA:SGD.
47	P39940	809	RSP5_YEAST E3 ubiquitin-protein ligase RSP5 O...	100	9.6	32.3	26	50	GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0005794; C:Golgi apparatus; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI.
									GO:0035091; F:phosphatidylinositol binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
									GO:0034644; P:cellular response to UV; IMP:SGD.::GO:0006333; P:chromatin assembly or disassembly; IMP:SGD.::GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IMP:SGD.::GO:0007005; P:mitochondrion organization; IMP:SGD.::GO:0045723; P:positive regulation of fatty acid biosynthetic process; IMP:SGD.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IPI:SGD.::GO:0006513; P:protein monoubiquitination; IMP:SGD.::GO:0000209; P:protein polyubiquitination; IMP:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0032956; P:regulation of actin cytoskeleton organization; IGI:SGD.::GO:0010794; P:regulation of dolichol biosynthetic process; IMP:SGD.::GO:0032443; P:regulation of ergosterol biosynthetic process; IMP:SGD.::GO:0010793; P:regulation of mRNA export from nucleus; IMP:SGD.::GO:0010796; P:regulation of multivesicular body size; IMP:SGD.::GO:0006808; P:regulation of nitrogen utilization; IGI:SGD.::GO:0019220; P:regulation of phosphate metabolic process; IGI:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:2000203; P:regulation of ribosomal large subunit export from nucleus; IMP:SGD.::GO:2000232; P:regulation of rRNA processing; IMP:SGD.::GO:2000238; P:regulation of tRNA export from nucleus; IMP:SGD.::GO:2000235; P:regulation of tRNA processing; IMP:SGD.::GO:0010795; P:regulation of ubiquinone biosynthetic process; IMP:SGD.::GO:0042493; P:response to drug; IMP:SGD.::GO:0034517; P:ribophagy; IGI:SGD.::GO:0070086; P:ubiquitin-dependent endocytosis; IMP:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.

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