UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPR120C

Length:

435

Number of sequences:

5887

Description:

YPR120C CLB5 SGDID:S000006324, Chr XVI from 775182-773875, Genome Release 64-1-1, reverse complement, Verified ORF, "B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	P39963	403	CCNB3_CHICK G2/mitotic-specific cyclin-B3 OS=...	241	2e-27	116	33	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
92	P04962	422	CCNA_SPISO G2/mitotic-specific cyclin-A OS=Sp...	216	2e-27	115	34	51	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
93	Q810T2	1396	CCNB3_MOUSE G2/mitotic-specific cyclin-B3 OS=...	239	6e-27	118	33	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
94	P24861	426	CCNA_PATVU G2/mitotic-specific cyclin-A OS=Pa...	191	6e-27	115	33	55	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
95	P47827	415	CCNA2_XENLA Cyclin-A2 OS=Xenopus laevis (Afri...	256	8e-27	114	31	51	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
96	P18606	418	CCNA1_XENLA Cyclin-A1 OS=Xenopus laevis (Afri...	222	6e-26	112	32	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
97	Q10654	385	CCNB3_CAEEL G2/mitotic-specific cyclin-B3 OS=...	229	6e-26	111	30	52	GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:WormBase.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007098; P:centrosome cycle; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0051383; P:kinetochore organization; IMP:WormBase.::GO:0045144; P:meiotic sister chromatid segregation; IMP:WormBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IMP:WormBase.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
98	P51943	422	CCNA2_MOUSE Cyclin-A2 OS=Mus musculus (Mouse)...	414	1e-25	110	26	44	GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001939; C:female pronucleus; IDA:MGI.::GO:0001940; C:male pronucleus; IDA:MGI.
									GO:0019901; F:protein kinase binding; IPI:MGI.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MGI.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
99	Q75I54	373	CCA31_ORYSJ Cyclin-A3-1 OS=Oryza sativa subsp...	264	5e-25	108	30	56	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
100	Q0JNK6	470	CCB13_ORYSJ Cyclin-B1-3 OS=Oryza sativa subsp...	270	7e-24	106	28	51	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
101	Q9SA32	396	CCB31_ARATH Putative cyclin-B3-1 OS=Arabidops...	210	7e-24	105	29	54	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
102	Q2QN26	385	CCA32_ORYSJ Cyclin-A3-2 OS=Oryza sativa subsp...	181	8e-24	105	31	59	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
103	P54733	709	CCNE_DROME G1/S-specific cyclin-E OS=Drosophi...	110	2e-23	107	45	69	GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007307; P:eggshell chorion gene amplification; IMP:FlyBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:FlyBase.::GO:0007259; P:JAK-STAT cascade; IGI:FlyBase.::GO:0007400; P:neuroblast fate determination; IMP:FlyBase.::GO:0048665; P:neuron fate specification; IDA:FlyBase.::GO:0007422; P:peripheral nervous system development; IEP:UniProtKB.::GO:0007277; P:pole cell development; IEP:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0006275; P:regulation of DNA replication; IMP:FlyBase.::GO:0007096; P:regulation of exit from mitosis; IGI:FlyBase.::GO:0001932; P:regulation of protein phosphorylation; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0045035; P:sensory organ precursor cell division; IMP:FlyBase.::GO:0035019; P:somatic stem cell maintenance; IDA:FlyBase.
104	P49707	407	CCNE1_CHICK G1/S-specific cyclin-E1 OS=Gallus...	111	2e-23	104	45	71	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
105	P43449	395	CCNA2_CHICK Cyclin-A2 OS=Gallus gallus (Chick...	367	3e-23	103	25	45	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
106	P37881	421	CCNA2_MESAU Cyclin-A2 OS=Mesocricetus auratus...	259	4e-23	103	29	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
107	P30274	430	CCNA2_BOVIN Cyclin-A2 OS=Bos taurus (Bovine)....	259	8e-23	103	29	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
108	O15995	424	CCNE_HEMPU G1/S-specific cyclin-E OS=pulcherr...	130	1e-22	102	41	64	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
109	Q92161	391	CCNA1_CARAU Cyclin-A1 OS=Carassius auratus (G...	149	1e-22	102	38	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
110	O96020	404	CCNE2_HUMAN G1/S-specific cyclin-E2 OS=Homo s...	102	2e-22	102	47	70	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000075; P:cell cycle checkpoint; TAS:ProtInc.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.
111	Q8WWL7	1395	CCNB3_HUMAN G2/mitotic-specific cyclin-B3 OS=...	258	2e-22	103	31	51	GO:0005634; C:nucleus; IDA:HPA.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
112	Q659K0	1330	CCNB3_CANFA G2/mitotic-specific cyclin-B3 OS=...	208	2e-22	103	32	53	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
113	P20248	432	CCNA2_HUMAN Cyclin-A2 OS=Homo sapiens (Human)...	259	2e-22	102	29	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
114	Q5E9K7	404	CCNE2_BOVIN G1/S-specific cyclin-E2 OS=Bos ta...	102	3e-22	101	47	70	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
115	Q9Z238	404	CCNE2_MOUSE G1/S-specific cyclin-E2 OS=Mus mu...	129	5e-22	100	43	60	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:MGI.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
116	P50756	408	CCNE1_XENLA G1/S-specific cyclin-E1 OS=Xenopu...	104	1e-21	99.4	45	71	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
117	Q91780	408	CCNE2_XENLA G1/S-specific cyclin-E2 OS=Xenopu...	104	1e-21	99.4	45	71	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
118	P14785	491	CCNA_DROME G2/mitotic-specific cyclin-A OS=Dr...	208	2e-21	100	28	53	GO:0045169; C:fusome; TAS:FlyBase.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0045170; C:spectrosome; TAS:FlyBase.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0055059; P:asymmetric neuroblast division; IMP:FlyBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; TAS:FlyBase.::GO:0035561; P:regulation of chromatin binding; IGI:FlyBase.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0007096; P:regulation of exit from mitosis; IMP:FlyBase.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.::GO:0007088; P:regulation of mitosis; IEP:UniProtKB.::GO:0009794; P:regulation of mitotic cell cycle, embryonic; IMP:FlyBase.::GO:0035186; P:syncytial blastoderm mitotic cell cycle; IGI:FlyBase.
119	O42575	408	CCNE3_XENLA G1/S-specific cyclin-E3 OS=Xenopu...	103	7e-21	97.4	44	73	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
120	P24864	410	CCNE1_HUMAN G1/S-specific cyclin-E1 OS=Homo s...	111	1e-20	96.7	41	68	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
									GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.
121	P47794	410	CCNE1_DANRE G1/S-specific cyclin-E1 OS=Danio ...	111	2e-20	95.9	41	68	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016301; F:kinase activity; IDA:ZFIN.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.

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