UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPR111W

Length:

564

Number of sequences:

5887

Description:

YPR111W DBF20 SGDID:S000006315, Chr XVI from 747306-749000, Genome Release 64-1-1, Verified ORF, "Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
631	B4HBU3	777	PLK4_DROPE Serine/threonine-protein kinase PL...	251	6e-18	91.3	25	43	GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
632	Q8VDU5	748	SNRK_MOUSE SNF-related serine/threonine-prote...	302	6e-18	91.3	27	43	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
633	Q923T9	529	KCC2G_MOUSE Calcium/calmodulin-dependent prot...	305	6e-18	90.5	24	42	GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
									GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IMP:MGI.
634	Q2LYK3	777	PLK4_DROPS Serine/threonine-protein kinase PL...	251	6e-18	91.3	25	43	GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
635	P43292	353	SRK2G_ARATH Serine/threonine-protein kinase S...	263	6e-18	89	24	41	GO:0005634; C:nucleus; IDA:TAIR.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0009651; P:response to salt stress; IDA:TAIR.
636	O80902	431	CIPKM_ARATH CBL-interacting serine/threonine-...	235	6e-18	90.1	30	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0007165; P:signal transduction; IEA:InterPro.
637	Q9JLM8	756	DCLK1_MOUSE Serine/threonine-protein kinase D...	280	6e-18	91.3	26	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0048675; P:axon extension; IGI:MGI.::GO:0021952; P:central nervous system projection neuron axonogenesis; IGI:MGI.::GO:0048813; P:dendrite morphogenesis; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001764; P:neuron migration; IGI:MGI.
638	B2GUY1	924	PLK4_RAT Serine/threonine-protein kinase PLK4...	250	7e-18	91.3	25	42	GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
									GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
639	Q4P5N0	746	STE20_USTMA Serine/threonine-protein kinase S...	241	7e-18	90.9	27	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
640	Q63553	746	SNRK_RAT SNF-related serine/threonine-protein...	302	7e-18	90.9	27	43	GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
									GO:0043523; P:regulation of neuron apoptotic process; TAS:UniProtKB.
641	O60285	661	NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS...	270	7e-18	90.9	23	43	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
									GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; IDA:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
642	Q8BZN4	639	NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS...	250	7e-18	90.9	26	44
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
									GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
643	P11730	527	KCC2G_RAT Calcium/calmodulin-dependent protei...	305	7e-18	90.5	25	41	GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0006979; P:response to oxidative stress; IDA:RGD.
644	A2BD05	313	NEK6_PIG Serine/threonine-protein kinase Nek6...	250	7e-18	88.2	26	40	GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
645	O60145	398	PPK23_SCHPO Serine/threonine-protein kinase p...	351	7e-18	89.4	28	44	GO:0005634; C:nucleus; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
									GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
646	Q54YF2	727	AMPKA_DICDI 5'-AMP-activated serine/threonine...	299	9e-18	90.9	26	43
									GO:0004679; F:AMP-activated protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006754; P:ATP biosynthetic process; IMP:dictyBase.::GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0007005; P:mitochondrion organization; IMP:dictyBase.::GO:0046956; P:positive phototaxis; IMP:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
647	Q9ES70	313	NEK6_MOUSE Serine/threonine-protein kinase Ne...	250	9e-18	87.8	26	40	GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.
648	P59895	313	NEK6_RAT Serine/threonine-protein kinase Nek6...	250	9e-18	87.8	26	40	GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.
649	P25390	1331	SSK22_YEAST Serine/threonine-protein kinase S...	311	9e-18	91.3	26	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD.
650	Q54WW7	695	Y0010_DICDI Probable serine/threonine-protein...	367	9e-18	90.5	27	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
651	Q75V57	361	SAPK9_ORYSJ Serine/threonine-protein kinase S...	309	9e-18	88.6	23	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
652	P54739	543	PKAA_STRCO Serine/threonine-protein kinase pk...	325	9e-18	90.1	25	39
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
653	Q4KTY1	415	KPSH1_PINFU Serine/threonine-protein kinase H...	254	1e-17	89.4	24	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
654	Q9NRH2	765	SNRK_HUMAN SNF-related serine/threonine-prote...	302	1e-17	90.5	26	43	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
									GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB.
655	Q6DEH3	491	KC2D1_DANRE Calcium/calmodulin-dependent prot...	305	1e-17	89.7	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
656	B3DL84	946	PLK4_XENTR Serine/threonine-protein kinase PL...	256	1e-17	90.9	25	44	GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
									GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.
657	P13234	474	KCC4_RAT Calcium/calmodulin-dependent protein...	242	1e-17	89.7	27	43	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
									GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.
658	P39009	513	DUN1_YEAST DNA damage response protein kinase...	243	1e-17	89.7	27	44	GO:0005634; C:nucleus; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0048478; P:replication fork protection; IGI:SGD.
659	Q9HC98	313	NEK6_HUMAN Serine/threonine-protein kinase Ne...	250	1e-17	87.8	26	40	GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000772; P:regulation of cellular senescence; TAS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB.
660	Q75H77	362	SAPKA_ORYSJ Serine/threonine-protein kinase S...	309	1e-17	88.2	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
661	B7XHR6	595	KIN1_ENTBH Probable serine/threonine-protein ...	410	1e-17	89.7	24	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0006887; P:exocytosis; IEA:UniProtKB-KW.

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