Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR106W
Length:
443
Number of sequences:
5887
Description:
YPR106W ISR1 SGDID:S000006310, Chr XVI from 740061-741392, Genome Release 64-1-1, Verified ORF, "Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06098    443   ISR1_YEAST Serine/threonine-protein kinase IS...4430     913     100     100
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
2Q758T2    342   ISR1_ASHGO Serine/threonine-protein kinase IS...2909e-60     204     37     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
3Q8CEE6    1383   PASK_MOUSE PAS domain-containing serine/threo...1600.00000002     60.8     28     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IMP:UniProtKB.::GO:0070092; P:regulation of glucagon secretion; IMP:UniProtKB.::GO:0043576; P:regulation of respiratory gaseous exchange; IMP:UniProtKB.
4Q96RG2    1323   PASK_HUMAN PAS domain-containing serine/threo...1600.00000004     59.3     28     46GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0070092; P:regulation of glucagon secretion; ISS:UniProtKB.::GO:0043576; P:regulation of respiratory gaseous exchange; ISS:UniProtKB.
5Q626B1    656   PMY13_CAEBR Membrane-associated tyrosine- and...2300.00000007     58.2     28     47GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0051327; P:M phase of meiotic cell cycle; ISS:UniProtKB.::GO:0051447; P:negative regulation of meiotic cell cycle; ISS:UniProtKB.::GO:0002119; P:nematode larval development; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
6Q8G4G1    757   PKNA2_BIFLO Probable serine/threonine-protein...1080.0000001     57.8     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
7Q2QXC6    417   WNK9_ORYSJ Probable serine/threonine-protein ...1290.0000004     55.5     29     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
8Q2RA93    439   WNK6_ORYSJ Probable serine/threonine-protein ...1170.0000004     55.5     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
9Q07292    813   KRAF1_CAEEL Raf homolog serine/threonine-prot...1120.0000005     55.8     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
GO:0001708; P:cell fate specification; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007265; P:Ras protein signal transduction; IGI:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
10Q61UC4    811   KRAF1_CAEBR Raf homolog serine/threonine-prot...1120.0000006     55.5     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
11Q54L00    650   LIMKA_DICDI Probable LIM domain-containing se...1500.0000007     55.1     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
12O74426    338   PPK33_SCHPO Serine/threonine-protein kinase p...2400.0000008     54.3     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
13Q8FUI4    520   PKN2_COREF Serine/threonine-protein kinases d...1460.000002     53.9     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
14Q7ZZC8    944   NEK9_XENLA Serine/threonine-protein kinase Ne...2740.000002     53.9     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
15Q54RR9    1761   Y9844_DICDI Probable serine/threonine-protein...2390.000002     53.9     27     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
16P54743    437   PKNA_MYCLE Probable serine/threonine-protein ...1120.000002     53.1     31     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
17P10533    367   RMIL_AVII1 Serine/threonine-protein kinase-tr...1370.000002     53.1     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
18Q08217    1101   PSK2_YEAST Serine/threonine-protein kinase PS...1070.000003     53.5     33     53GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
19P27966    450   RMIL_AVEVR Serine/threonine-protein kinase-tr...1370.000003     52.8     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
20Q753D9    726   PKH3_ASHGO Serine/threonine-protein kinase PK...1410.000003     53.1     26     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
21P00532    323   RAF_MSV36 Serine/threonine-protein kinase-tra...1660.000003     52.4     28     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
22Q12236    1081   PKH2_YEAST Serine/threonine-protein kinase PK...1170.000004     53.1     34     48GO:0032126; C:eisosome; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
23O34507    648   PRKC_BACSU Serine/threonine-protein kinase Pr...1670.000004     52.8     30     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0071224; P:cellular response to peptidoglycan; IMP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB.::GO:0009847; P:spore germination; IMP:UniProtKB.
24O00506    426   STK25_HUMAN Serine/threonine-protein kinase 2...1810.000004     52.4     24     45GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006979; P:response to oxidative stress; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
25Q558U1    2258   IFKA_DICDI Probable serine/threonine-protein ...1840.000004     53.1     30     46GO:0005622; C:intracellular; IC:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IMP:dictyBase.::GO:0000049; F:tRNA binding; IEA:InterPro.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0019933; P:cAMP-mediated signaling; IMP:dictyBase.::GO:0016337; P:cell-cell adhesion; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IGI:dictyBase.::GO:0048255; P:mRNA stabilization; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0006446; P:regulation of translational initiation; ISS:dictyBase.
26P0CD62    966   LIMKB_DICDI Probable LIM domain-containing se...1460.000004     52.8     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27Q550L8    1358   IFKB_DICDI Probable serine/threonine-protein ...1840.000005     52.8     30     46GO:0005622; C:intracellular; IC:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:dictyBase.::GO:0000049; F:tRNA binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IGI:dictyBase.
28Q99N57    648   RAF1_MOUSE RAF proto-oncogene serine/threonin...1660.000005     52.4     28     43GO:0005829; C:cytosol; TAS:MGI.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0031143; C:pseudopodium; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017016; F:Ras GTPase binding; IPI:MGI.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI.
29Q3SWY6    426   STK25_BOVIN Serine/threonine-protein kinase 2...1810.000006     52     24     45GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
30P28028    804   BRAF_MOUSE Serine/threonine-protein kinase B-...1370.000006     52.4     28     46GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
31P10421    342   MOS_MSVTS Serine/threonine-protein kinase-tra...1030.000006     51.6     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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