Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR106W
Length:
443
Number of sequences:
5887
Description:
YPR106W ISR1 SGDID:S000006310, Chr XVI from 740061-741392, Genome Release 64-1-1, Verified ORF, "Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
811Q63184    513   E2AK2_RAT Interferon-induced, double-stranded...1020.083     38.9     30     50GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033689; P:negative regulation of osteoblast proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0043330; P:response to exogenous dsRNA; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IMP:RGD.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0033197; P:response to vitamin E; IPI:RGD.
812P87253    1142   KPC1_NEUCR Protein kinase C-like OS=1257 / FG...1040.084     39.3     30     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
813Q9SKG5    620   SERK4_ARATH Somatic embryogenesis receptor ki...950.084     38.9     27     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0033612; F:receptor serine/threonine kinase binding; IPI:UniProtKB.::GO:0004675; F:transmembrane receptor protein serine/threonine kinase activity; ISS:TAIR.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC.
GO:0009742; P:brassinosteroid mediated signaling pathway; IGI:TAIR.::GO:0008219; P:cell death; IGI:TAIR.::GO:0010150; P:leaf senescence; IGI:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.
814Q8TDR2    534   STK35_HUMAN Serine/threonine-protein kinase 3...2700.085     38.9     24     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
815Q96285    661   LRK55_ARATH L-type lectin-domain containing r...1140.085     38.9     32     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
816Q9LQQ9    363   MPK13_ARATH Mitogen-activated protein kinase ...1490.085     38.5     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
817O75011    652   NAK1_SCHPO Serine/threonine-protein kinase na...1070.085     38.9     27     50GO:0030479; C:actin cortical patch; TAS:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030037; P:actin filament reorganization involved in cell cycle; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033554; P:cellular response to stress; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:PomBase.::GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.
818Q8BTW9    593   PAK4_MOUSE Serine/threonine-protein kinase PA...1030.085     38.9     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
819Q9FKW4    523   CDPKS_ARATH Calcium-dependent protein kinase ...2330.086     38.9     22     39GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
820Q9LSL5    675   LRK92_ARATH L-type lectin-domain containing r...980.086     38.9     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
821Q5R754    493   CDKL2_PONAB Cyclin-dependent kinase-like 2 OS...2260.086     38.9     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
822P24723    683   KPCL_HUMAN Protein kinase C eta type OS=Homo ...1030.086     38.9     29     46GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; IMP:UniProtKB.
823Q7YRC6    344   AURKB_BOVIN Aurora kinase B OS=Bos taurus (Bo...1080.086     38.5     24     47GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
824F1QGZ6    676   MELK_DANRE Maternal embryonic leucine zipper ...1600.087     38.9     24     44GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048821; P:erythrocyte development; IMP:ZFIN.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008016; P:regulation of heart contraction; IMP:ZFIN.
825P80202    505   ACV1B_RAT Activin receptor type-1B OS=Rattus ...840.087     38.9     35     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016361; F:activin receptor activity, type I; IMP:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IMP:RGD.::GO:0046332; F:SMAD binding; IMP:RGD.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
GO:0007417; P:central nervous system development; IEP:RGD.::GO:0046545; P:development of primary female sexual characteristics; IEP:RGD.::GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.
826P38070    525   YPK3_YEAST AGC kinase YPK3 OS=Saccharomyces c...1550.087     38.9     26     45GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
827P36896    505   ACV1B_HUMAN Activin receptor type-1B OS=Homo ...840.087     38.9     35     51GO:0009986; C:cell surface; IDA:HGNC.::GO:0005887; C:integral to plasma membrane; IDA:HGNC.
GO:0016361; F:activin receptor activity, type I; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:HGNC.::GO:0034711; F:inhibin binding; IPI:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046332; F:SMAD binding; IDA:HGNC.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:HGNC.::GO:0006917; P:induction of apoptosis; IMP:HGNC.::GO:0030308; P:negative regulation of cell growth; IDA:HGNC.::GO:0038092; P:nodal signaling pathway; IGI:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0032927; P:positive regulation of activin receptor signaling pathway; IDA:BHF-UCL.::GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:HGNC.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:HGNC.
828Q7RJG2    528   CDPK4_PLAYO Calcium-dependent protein kinase ...1100.088     38.9     25     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
829O80902    431   CIPKM_ARATH CBL-interacting serine/threonine-...2330.088     38.9     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
830Q2QYM3    439   CIPKE_ORYSJ CBL-interacting protein kinase 14...1330.089     38.9     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
831Q2RBF0    434   CIPKF_ORYSJ CBL-interacting protein kinase 15...1330.089     38.9     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
832O15021    2626   MAST4_HUMAN Microtubule-associated serine/thr...1600.089     39.3     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
833P62345    528   CDPK4_PLABA Calcium-dependent protein kinase ...1100.09     38.9     25     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
834Q9C7S5    1095   PSYR1_ARATH Tyrosine-sulfated glycopeptide re...930.091     38.9     31     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0001653; F:peptide receptor activity; IMP:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004888; F:transmembrane signaling receptor activity; IMP:TAIR.
GO:0009611; P:response to wounding; IGI:TAIR.
835Q61851    801   FGFR3_MOUSE Fibroblast growth factor receptor...2560.092     38.9     21     38GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0070977; P:bone maturation; IMP:BHF-UCL.::GO:0048640; P:negative regulation of developmental growth; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; ISS:UniProtKB.::GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; ISS:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.::GO:0035121; P:tail morphogenesis; IMP:BHF-UCL.
836A8WRV1    813   KIN29_CAEBR Serine/threonine-protein kinase k...1040.092     38.9     32     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
837P24583    1151   KPC1_YEAST Protein kinase C-like 1 OS=Sacchar...1020.095     38.9     31     48GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005856; C:cytoskeleton; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0030427; C:site of polarized growth; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IDA:SGD.
GO:0007015; P:actin filament organization; IGI:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0007243; P:intracellular protein kinase cascade; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IMP:SGD.
838A3EZ55    278   HOG1_WALIC Mitogen-activated protein kinase H...1120.095     38.1     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
839O23236    361   MPK14_ARATH Mitogen-activated protein kinase ...1020.095     38.5     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
840Q54WS5    2147   ROCO6_DICDI Probable serine/threonine-protein...1190.095     38.9     24     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
841Q61271    505   ACV1B_MOUSE Activin receptor type-1B OS=Mus m...840.095     38.9     35     51
GO:0048185; F:activin binding; IPI:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
GO:0001942; P:hair follicle development; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
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