Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR106W
Length:
443
Number of sequences:
5887
Description:
YPR106W ISR1 SGDID:S000006310, Chr XVI from 740061-741392, Genome Release 64-1-1, Verified ORF, "Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721Q92772    493   CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS...2260.051     39.7     24     42GO:0005813; C:centrosome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007548; P:sex differentiation; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
722Q4R7T5    570   CDKL2_MACFA Cyclin-dependent kinase-like 2 OS...2260.051     39.7     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
723P90866    588   CDK8_CAEEL Cyclin-dependent kinase 8 OS=Caeno...2390.051     39.7     23     45GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
724Q9MAM1    447   CIPK9_ARATH CBL-interacting serine/threonine-...1100.051     39.7     25     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051365; P:cellular response to potassium ion starvation; IMP:TAIR.::GO:0043266; P:regulation of potassium ion transport; IMP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0010555; P:response to mannitol stimulus; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
725P50526    652   SSP1_SCHPO Serine/threonine-protein kinase ss...1570.052     39.7     28     45GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030042; P:actin filament depolymerization; IGI:PomBase.::GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033554; P:cellular response to stress; IMP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
726Q55EI8    1385   Y9956_DICDI Probable serine/threonine-protein...1120.052     39.7     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
727Q8GUH1    834   PUB33_ARATH U-box domain-containing protein 3...980.052     39.7     35     50GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0006950; P:response to stress; IEA:InterPro.
728Q8RXE5    524   WNK10_ARATH Probable serine/threonine-protein...1670.053     39.7     27     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
729O61661    512   CHK1_DROME Serine/threonine-protein kinase gr...1090.053     39.7     25     46GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0007050; P:cell cycle arrest; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0051299; P:centrosome separation; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007444; P:imaginal disc development; TAS:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007348; P:regulation of syncytial blastoderm mitotic cell cycle; IMP:UniProtKB.::GO:0009314; P:response to radiation; TAS:FlyBase.::GO:0051225; P:spindle assembly; IMP:FlyBase.
730B5VNQ3    717   STE11_YEAS6 Serine/threonine-protein kinase S...1200.053     39.7     26     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
731P33886    605   WIS1_SCHPO Protein kinase wis1 OS=Schizosacch...2170.053     39.7     23     41GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; NAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; TAS:PomBase.::GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0043555; P:regulation of translation in response to stress; IMP:PomBase.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0051403; P:stress-activated MAPK cascade; TAS:PomBase.
732Q811L6    2618   MAST4_MOUSE Microtubule-associated serine/thr...1600.053     40     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
733Q9TVL3    478   CDK9_CAEEL Probable cyclin-dependent kinase 9...1380.054     39.7     28     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006479; P:protein methylation; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
734Q9H422    1215   HIPK3_HUMAN Homeodomain-interacting protein k...1060.054     39.7     30     57GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0009299; P:mRNA transcription; IDA:UniProtKB.::GO:0043508; P:negative regulation of JUN kinase activity; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
735O60307    1309   MAST3_HUMAN Microtubule-associated serine/thr...1600.054     39.7     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
736P28708    518   PRR1_YEAST Serine/threonine-protein kinase PR...1510.054     39.7     25     46GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IMP:SGD.
GO:0031138; P:negative regulation of conjugation with cellular fusion; IMP:SGD.::GO:0046020; P:negative regulation of transcription from RNA polymerase II promoter by pheromones; IMP:SGD.
737Q8RWC9    444   CIPK1_ARATH CBL-interacting serine/threonine-...1290.054     39.3     25     47GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
738Q12469    655   SKM1_YEAST Serine/threonine-protein kinase SK...1490.054     39.7     26     48GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000920; P:cytokinetic cell separation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.
739Q802A6    491   STK4_SQUAC Serine/threonine-protein kinase 3/...980.055     39.3     29     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.
740Q8VZJ9    411   Y4330_ARATH Probable leucine-rich repeat rece...2900.056     39.3     23     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009555; P:pollen development; IMP:TAIR.
741Q5MAI5    315   CDKL4_HUMAN Cyclin-dependent kinase-like 4 OS...2260.056     39.3     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
742P93194    1109   RPK1_IPONI Receptor-like protein kinase OS=Ip...930.057     39.7     32     54GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; NAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0019199; F:transmembrane receptor protein kinase activity; NAS:UniProtKB.
743Q6FQ83    667   BUR1_CANGA Serine/threonine-protein kinase BU...1170.057     39.7     27     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
744Q8T0S6    669   HIPPO_DROME Serine/threonine-protein kinase h...990.058     39.7     31     46GO:0016020; C:membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:FlyBase.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:FlyBase.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:FlyBase.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:FlyBase.::GO:0046621; P:negative regulation of organ growth; TAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IDA:FlyBase.
745Q75GK4    447   CIPK7_ORYSJ CBL-interacting protein kinase 7 ...1090.058     39.3     24     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
746Q62925    1493   M3K1_RAT Mitogen-activated protein kinase kin...1490.059     39.7     25     40GO:0005737; C:cytoplasm; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008432; F:JUN kinase binding; IPI:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0004710; F:MAPK/ERK kinase kinase activity; IDA:RGD.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0046625; F:sphingolipid binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0050434; P:positive regulation of viral transcription; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0051259; P:protein oligomerization; IDA:RGD.::GO:0000209; P:protein polyubiquitination; IMP:RGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IGI:RGD.::GO:0006970; P:response to osmotic stress; IMP:RGD.
747Q9JKV2    629   ICK_MOUSE Serine/threonine-protein kinase ICK...1020.059     39.3     27     50GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
748Q6ZAG3    324   CDKC3_ORYSJ Cyclin-dependent kinase C-3 OS=Or...1010.059     38.9     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
749Q96VK3    544   BUR1_EMENI Serine/threonine-protein kinase bu...1180.06     39.3     27     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
750Q9S9M2    761   WAKLD_ARATH Wall-associated receptor kinase-l...1040.06     39.7     30     46GO:0009986; C:cell surface; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0010045; P:response to nickel cation; IEP:TAIR.::GO:0010043; P:response to zinc ion; IEP:TAIR.
751O14328    474   KSP1_SCHPO Serine/threonine-protein kinase ks...1050.061     39.3     30     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
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