Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR106W
Length:
443
Number of sequences:
5887
Description:
YPR106W ISR1 SGDID:S000006310, Chr XVI from 740061-741392, Genome Release 64-1-1, Verified ORF, "Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
691Q4R8T9    590   CDKL3_MACFA Cyclin-dependent kinase-like 3 OS...1030.041     40     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
692P43250    576   GRK6_HUMAN G protein-coupled receptor kinase ...1480.042     40     24     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
693Q6BS08    875   ATG1_DEBHA Serine/threonine-protein kinase AT...3110.042     40     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
694A3EZ54    278   HOG1_WALSE Mitogen-activated protein kinase H...1590.042     39.3     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
695Q9ZNQ8    633   PERK4_ARATH Proline-rich receptor-like protei...950.042     40     34     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0019722; P:calcium-mediated signaling; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0009845; P:seed germination; IMP:TAIR.
696Q86AT8    638   SPKA_DICDI Stress-activated protein kinase al...2180.042     40     23     43GO:0015629; C:actin cytoskeleton; IDA:dictyBase.::GO:0005737; C:cytoplasm; IDA:dictyBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0050793; P:regulation of developmental process; IMP:dictyBase.::GO:0006970; P:response to osmotic stress; IDA:dictyBase.
697Q8N165    341   PDK1L_HUMAN Serine/threonine-protein kinase P...3140.043     39.7     25     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
698C0LGX1    607   Y5524_ARATH Probable LRR receptor-like serine...1200.043     40     25     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
699O14408    382   KCC1_METAN Calcium/calmodulin-dependent prote...1090.043     39.7     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
700P08414    469   KCC4_MOUSE Calcium/calmodulin-dependent prote...1440.043     39.7     25     46GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:MGI.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0007270; P:neuron-neuron synaptic transmission; IMP:MGI.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MGI.::GO:0007165; P:signal transduction; IDA:MGI.
701Q9U1Y5    476   CHK2_CAEEL Serine/threonine-protein kinase ch...1070.044     39.7     31     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
702P28652    542   KCC2B_MOUSE Calcium/calmodulin-dependent prot...1860.044     39.7     22     42GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:MGI.
GO:0060466; P:activation of meiosis involved in egg activation; IMP:MGI.::GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0031558; P:induction of apoptosis in response to chemical stimulus; IDA:MGI.::GO:0002030; P:inhibitory G-protein coupled receptor phosphorylation; IDA:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.::GO:0032222; P:regulation of synaptic transmission, cholinergic; IMP:MGI.::GO:0046686; P:response to cadmium ion; IDA:MGI.
703Q55FJ6    507   Y8078_DICDI Probable serine/threonine-protein...1040.044     39.7     32     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
704O88850    1191   HIPK3_RAT Homeodomain-interacting protein kin...1060.044     40     30     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
705Q9P2K8    1649   E2AK4_HUMAN Eukaryotic translation initiation...1970.044     40     24     40GO:0022626; C:cytosolic ribosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:InterPro.
706Q8INB9    611   AKT1_DROME RAC serine/threonine-protein kinas...1030.044     39.7     29     46GO:0009986; C:cell surface; IDA:FlyBase.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; NAS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; NAS:FlyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:FlyBase.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008362; P:chitin-based embryonic cuticle biosynthetic process; IGI:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0035556; P:intracellular signal transduction; IGI:UniProtKB.::GO:0019915; P:lipid storage; IGI:FlyBase.::GO:0060292; P:long term synaptic depression; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; TAS:FlyBase.::GO:0046622; P:positive regulation of organ growth; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0050773; P:regulation of dendrite development; IMP:FlyBase.::GO:0042306; P:regulation of protein import into nucleus; TAS:FlyBase.
707Q8SRL5    272   IPL1_ENCCU Probable spindle assembly checkpoi...1060.045     39.3     25     48GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
708P46551    730   CDK12_CAEEL Cyclin-dependent kinase 12 OS=Cae...1080.045     40     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
709Q8GYQ5    372   MPK12_ARATH Mitogen-activated protein kinase ...1050.045     39.7     31     52GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0009734; P:auxin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0080026; P:response to indolebutyric acid stimulus; IMP:TAIR.
710Q9FIF0    694   LRK22_ARATH Putative L-type lectin-domain con...890.046     40     35     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
711Q9LN59    788   WAKLK_ARATH Putative wall-associated receptor...1320.046     40     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
712P47355    387   PKNS_MYCGE Putative serine/threonine-protein ...1160.047     39.7     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
713P34103    992   PK4_DICDI Protein kinase 4 OS=Dictyostelium d...1180.047     40     29     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
714Q02779    954   M3K10_HUMAN Mitogen-activated protein kinase ...1030.047     40     32     53GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB.
715Q9ERH7    1192   HIPK3_MOUSE Homeodomain-interacting protein k...1060.047     40     30     57GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB.
716Q5VST9    7968   OBSCN_HUMAN Obscurin OS=Homo sapiens (Human)....1060.048     40     27     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; ISS:BHF-UCL.::GO:0030018; C:Z disc; ISS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; NAS:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
717P13234    474   KCC4_RAT Calcium/calmodulin-dependent protein...1440.048     39.7     25     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.
718Q8SQW2    329   CTK1_ENCCU Probable CTD kinase subunit alpha ...970.049     39.3     29     54GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
719B5DE93    1239   CDK12_XENTR Cyclin-dependent kinase 12 OS=Xen...1050.049     40     30     49GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
720Q6AX33    1482   MAST3_XENLA Microtubule-associated serine/thr...1570.05     40     29     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
721Q92772    493   CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS...2260.051     39.7     24     42GO:0005813; C:centrosome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007548; P:sex differentiation; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
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