rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P10421 | 342 | MOS_MSVTS Serine/threonine-protein kinase-tra... | 103 | 0.000006 | 51.6 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 32 | Q04982 | 806 | BRAF_CHICK Serine/threonine-protein kinase B-... | 137 | 0.000006 | 52.4 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 33 | P34908 | 807 | BRAF_COTJA Serine/threonine-protein kinase B-... | 137 | 0.000006 | 52.4 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 34 | P15056 | 766 | BRAF_HUMAN Serine/threonine-protein kinase B-... | 137 | 0.000006 | 52.4 | 28 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 35 | P65726 | 431 | PKNA_MYCTU Probable serine/threonine-protein ... | 112 | 0.000007 | 52 | 30 | 47 | GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005576; C:extracellular region; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0051055; P:negative regulation of lipid biosynthetic process; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0008360; P:regulation of cell shape; IDA:MTBBASE. | 36 | P65727 | 431 | PKNA_MYCBO Probable serine/threonine-protein ... | 112 | 0.000007 | 52 | 30 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 37 | P54739 | 543 | PKAA_STRCO Serine/threonine-protein kinase pk... | 147 | 0.000007 | 52 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | Q11053 | 626 | PKNH_MYCTU Probable serine/threonine-protein ... | 233 | 0.000008 | 52 | 25 | 41 | GO:0005887; C:integral to plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0045926; P:negative regulation of growth; IMP:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0046890; P:regulation of lipid biosynthetic process; IMP:MTBBASE.::GO:0052572; P:response to host immune response; IEP:MTBBASE.::GO:0006950; P:response to stress; IEP:MTBBASE. | 39 | Q7U095 | 596 | PKNH_MYCBO Probable serine/threonine-protein ... | 233 | 0.000009 | 51.6 | 25 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 40 | P38692 | 1080 | KIC1_YEAST Serine/threonine-protein kinase KI... | 115 | 0.00001 | 51.6 | 31 | 53 | GO:0005933; C:cellular bud; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007118; P:budding cell apical bud growth; IMP:SGD.::GO:0000902; P:cell morphogenesis; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD. | 41 | O05871 | 664 | PKND_MYCTU Serine/threonine-protein kinase pk... | 236 | 0.00001 | 51.6 | 26 | 39 | GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005887; C:integral to plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IDA:MTBBASE.::GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0032091; P:negative regulation of protein binding; IDA:MTBBASE.::GO:0009405; P:pathogenesis; IMP:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE. | 42 | P09560 | 638 | RAF1_XENLA RAF proto-oncogene serine/threonin... | 110 | 0.00001 | 51.2 | 27 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 43 | Q7SY52 | 974 | STK10_DANRE Serine/threonine-protein kinase 1... | 151 | 0.00001 | 51.6 | 28 | 51 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 44 | O14132 | 650 | PIT1_SCHPO Sporulation protein kinase pit1 OS... | 229 | 0.00001 | 51.2 | 28 | 45 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; NAS:PomBase. | 45 | Q9Z2W1 | 426 | STK25_MOUSE Serine/threonine-protein kinase 2... | 181 | 0.00001 | 50.8 | 24 | 45 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.::GO:0051645; P:Golgi localization; IMP:MGI.::GO:0050772; P:positive regulation of axonogenesis; IMP:MGI. | 46 | Q8T2I8 | 1167 | SEPA_DICDI Serine/threonine-protein kinase se... | 114 | 0.00001 | 51.2 | 32 | 53 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 47 | Q39008 | 608 | M3K1_ARATH Mitogen-activated protein kinase k... | 144 | 0.00001 | 50.8 | 29 | 46 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IDA:TAIR.::GO:0019900; F:kinase binding; IPI:TAIR.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:TAIR. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009611; P:response to wounding; IDA:TAIR. | 48 | P79432 | 303 | CDK4_PIG Cyclin-dependent kinase 4 OS=Sus scr... | 105 | 0.00001 | 50.1 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 49 | Q5R5M7 | 648 | RAF1_PONAB RAF proto-oncogene serine/threonin... | 166 | 0.00002 | 50.8 | 27 | 43 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 50 | P04049 | 648 | RAF1_HUMAN RAF proto-oncogene serine/threonin... | 166 | 0.00002 | 50.8 | 27 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:UniProtKB.::GO:0031333; P:negative regulation of protein complex assembly; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045595; P:regulation of cell differentiation; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; TAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 51 | P11345 | 648 | RAF1_RAT RAF proto-oncogene serine/threonine-... | 166 | 0.00002 | 50.8 | 27 | 43 | GO:0005829; C:cytosol; TAS:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IMP:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD. | | | | | | | | | | GO:0007507; P:heart development; IEP:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD. | 52 | B2MVY4 | 303 | CDK4_SHEEP Cyclin-dependent kinase 4 OS=Ovis ... | 105 | 0.00002 | 50.1 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 53 | Q32KY4 | 303 | CDK4_BOVIN Cyclin-dependent kinase 4 OS=Bos t... | 105 | 0.00002 | 50.1 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 54 | P11802 | 303 | CDK4_HUMAN Cyclin-dependent kinase 4 OS=Homo ... | 105 | 0.00002 | 50.1 | 34 | 54 | GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0010468; P:regulation of gene expression; IMP:BHF-UCL.::GO:0042493; P:response to drug; IGI:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome. | 55 | P41720 | 274 | PK1_NPVLD Serine/threonine-protein kinase 1 O... | 107 | 0.00002 | 49.7 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 56 | Q84TI6 | 470 | CDKE1_ARATH Cyclin-dependent kinase E-1 OS=Ar... | 132 | 0.00002 | 50.4 | 33 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 57 | Q86HN7 | 978 | PLK_DICDI Probable serine/threonine-protein k... | 103 | 0.00002 | 50.8 | 32 | 54 | GO:0005813; C:centrosome; TAS:dictyBase.::GO:0005819; C:spindle; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0007067; P:mitosis; ISS:dictyBase. | 58 | O53510 | 399 | PKNL_MYCTU Probable serine/threonine-protein ... | 113 | 0.00002 | 50.1 | 29 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE. | | | | | | | | | | GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE. | 59 | Q7TYY6 | 399 | PKNL_MYCBO Probable serine/threonine-protein ... | 113 | 0.00002 | 50.1 | 29 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 60 | P15442 | 1659 | GCN2_YEAST Serine/threonine-protein kinase GC... | 168 | 0.00002 | 50.8 | 26 | 43 | GO:0022626; C:cytosolic ribosome; IDA:SGD. | | | | | | | | | | GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0000049; F:tRNA binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IMP:SGD.::GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.::GO:0006412; P:translation; IEA:UniProtKB-KW. | 61 | P33973 | 693 | PKN1_MYXXA Serine/threonine-protein kinase Pk... | 109 | 0.00002 | 50.4 | 31 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035438; F:cyclic-di-GMP binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |