Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR106W
Length:
443
Number of sequences:
5887
Description:
YPR106W ISR1 SGDID:S000006310, Chr XVI from 740061-741392, Genome Release 64-1-1, Verified ORF, "Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q8BG48    372   ST17B_MOUSE Serine/threonine-protein kinase 1...1280.002     43.9     24     50GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
302P12965    359   MOS_XENLA Serine/threonine-protein kinase mos...1600.002     43.9     26     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
303D0N4E2    399   PKZ1_PHYIT Serine/threonine-protein kinase PK...1210.002     44.3     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
304Q8SSH1    516   Y255_ENCCU Probable serine/threonine-protein ...1130.002     44.3     23     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
305B4KYX8    778   PLK4_DROMO Serine/threonine-protein kinase PL...1490.002     44.3     26     52GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
306P38991    367   IPL1_YEAST Spindle assembly checkpoint kinase...1470.002     43.9     29     44GO:0032133; C:chromosome passenger complex; IDA:SGD.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005828; C:kinetochore microtubule; IDA:SGD.::GO:0051233; C:spindle midzone; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:SGD.::GO:0045143; P:homologous chromosome segregation; IMP:SGD.::GO:0045144; P:meiotic sister chromatid segregation; IMP:SGD.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0051228; P:mitotic spindle disassembly; IMP:SGD.::GO:0032465; P:regulation of cytokinesis; IMP:SGD.::GO:0031577; P:spindle checkpoint; IMP:SGD.
307P42818    465   KPK1_ARATH Serine/threonine-protein kinase At...1460.002     44.3     28     42GO:0005737; C:cytoplasm; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
308Q0IHQ8    951   STK10_XENTR Serine/threonine-protein kinase 1...1140.002     44.7     28     53GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
309Q8W4P1    513   CDKC2_ARATH Cyclin-dependent kinase C-2 OS=Ar...1040.002     44.3     32     51GO:0005829; C:cytosol; IDA:TAIR.::GO:0016604; C:nuclear body; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0048440; P:carpel development; IGI:TAIR.::GO:0048366; P:leaf development; IGI:TAIR.::GO:0006397; P:mRNA processing; IEP:TAIR.::GO:0050792; P:regulation of viral reproduction; IMP:TAIR.::GO:0009615; P:response to virus; IEP:TAIR.
310Q91XS8    371   ST17B_RAT Serine/threonine-protein kinase 17B...1280.002     43.9     24     50GO:0015629; C:actin cytoskeleton; IMP:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.
311Q8N4C8    1332   MINK1_HUMAN Misshapen-like kinase 1 OS=Homo s...1170.002     44.7     24     48GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.::GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; IMP:UniProtKB.::GO:0001952; P:regulation of cell-matrix adhesion; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; ISS:UniProtKB.
312O61267    476   LOK_DROME Ovarian-specific serine/threonine-p...1740.002     44.3     26     46GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:BHF-UCL.::GO:0007281; P:germ cell development; IEP:UniProtKB.::GO:0035234; P:germ cell programmed cell death; IMP:FlyBase.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL.
313Q6P431    467   MKNK2_XENLA MAP kinase-interacting serine/thr...1160.002     43.9     25     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
314Q9Z1B7    366   MK13_MOUSE Mitogen-activated protein kinase 1...980.002     43.9     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
315Q32PI1    396   VRK1_BOVIN Serine/threonine-protein kinase VR...2550.002     43.9     22     40GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:AgBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090166; P:Golgi disassembly; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:AgBase.
316F1LP90    1336   MINK1_RAT Misshapen-like kinase 1 OS=Rattus n...1170.002     44.3     24     48GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0048813; P:dendrite morphogenesis; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; IMP:UniProtKB.
317B3M6I4    770   PLK4_DROAN Serine/threonine-protein kinase PL...1480.002     44.3     30     51GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
318Q8QZV4    488   ST32C_MOUSE Serine/threonine-protein kinase 3...1060.002     43.9     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
319C0LGV0    895   Y5487_ARATH Probable LRR receptor-like serine...2460.002     44.3     25     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
320Q9UEE5    414   ST17A_HUMAN Serine/threonine-protein kinase 1...1130.002     43.9     28     52GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
321Q3UMM4    360   CDK10_MOUSE Cyclin-dependent kinase 10 OS=Mus...1060.002     43.9     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
322P92937    421   CIPKF_ARATH CBL-interacting serine/threonine-...1660.002     43.9     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:TAIR.
323Q7RX99    932   ATG1_NEUCR Serine/threonine-protein kinase at...1720.002     44.3     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
324P39073    555   SSN3_YEAST Meiotic mRNA stability protein kin...1020.002     43.9     30     47GO:0016592; C:mediator complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:SGD.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0060258; P:negative regulation of filamentous growth; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IMP:SGD.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0000435; P:positive regulation of transcription from RNA polymerase II promoter by galactose; IMP:SGD.::GO:0031648; P:protein destabilization; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
325Q9JM52    1308   MINK1_MOUSE Misshapen-like kinase 1 OS=Mus mu...1170.002     44.3     24     48GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0007268; P:synaptic transmission; ISS:UniProtKB.
326Q66I46    466   MKNK2_XENTR MAP kinase-interacting serine/thr...1160.002     43.9     25     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
327Q00097    380   KR15_ICHVA Protein kinase ORF15 OS=herpesviru...1310.002     43.5     30     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
328Q6DD27    896   TAOK3_XENLA Serine/threonine-protein kinase T...1730.002     44.3     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:UniProtKB.
329Q23977    1178   HEP_DROME Dual specificity mitogen-activated ...1120.002     44.3     29     46GO:0030424; C:axon; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008545; F:JUN kinase kinase activity; TAS:FlyBase.::GO:0005078; F:MAP-kinase scaffold activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:FlyBase.
GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0048675; P:axon extension; IMP:FlyBase.::GO:0034769; P:basement membrane disassembly; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IGI:FlyBase.::GO:0033500; P:carbohydrate homeostasis; IMP:FlyBase.::GO:0071243; P:cellular response to arsenic-containing substance; IMP:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IMP:FlyBase.::GO:0030381; P:chorion-containing eggshell pattern formation; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0001736; P:establishment of planar polarity; NAS:FlyBase.::GO:0046847; P:filopodium assembly; IMP:FlyBase.::GO:0007561; P:imaginal disc eversion; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; TAS:FlyBase.::GO:0030032; P:lamellipodium assembly; IMP:FlyBase.::GO:0035006; P:melanization defense response; IMP:FlyBase.::GO:0046844; P:micropyle formation; IMP:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0070328; P:triglyceride homeostasis; IMP:FlyBase.::GO:0042060; P:wound healing; IMP:FlyBase.
330O01700    928   DLK1_CAEEL Mitogen-activated protein kinase k...1230.002     44.3     24     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0045202; C:synapse; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:WormBase.
GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IGI:WormBase.
331Q8SW31    566   KIN1_ENCCU Probable serine/threonine-protein ...1920.002     43.9     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
records
Previous ‹‹ ›› Next Total records: 1000 301 - 330
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::