rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q9BZS1 | 431 | FOXP3_HUMAN Forkhead box protein P3 OS=Homo s... | 94 | 0.000002 | 54.7 | 31 | 60 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0035035; F:histone acetyltransferase binding; IPI:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0051059; F:NF-kappaB binding; NAS:UniProtKB.::GO:0051525; F:NFAT protein binding; IPI:UniProtKB.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0003714; F:transcription corepressor activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001782; P:B cell homeostasis; IBA:RefGenome.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0006338; P:chromatin remodeling; NAS:UniProtKB.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0002262; P:myeloid cell homeostasis; IBA:RefGenome.::GO:0046007; P:negative regulation of activated T cell proliferation; NAS:UniProtKB.::GO:0002677; P:negative regulation of chronic inflammatory response; IBA:RefGenome.::GO:0032792; P:negative regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0050710; P:negative regulation of cytokine secretion; IDA:UniProtKB.::GO:0035067; P:negative regulation of histone acetylation; IBA:RefGenome.::GO:0031064; P:negative regulation of histone deacetylation; IGI:BHF-UCL.::GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; IBA:RefGenome.::GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.::GO:0032693; P:negative regulation of interleukin-10 production; IDA:UniProtKB.::GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; IMP:UniProtKB.::GO:0032703; P:negative regulation of interleukin-2 production; IDA:UniProtKB.::GO:0032713; P:negative regulation of interleukin-4 production; IDA:UniProtKB.::GO:0032714; P:negative regulation of interleukin-5 production; IBA:RefGenome.::GO:0032715; P:negative regulation of interleukin-6 production; IBA:RefGenome.::GO:0048294; P:negative regulation of isotype switching to IgE isotypes; IBA:RefGenome.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0002725; P:negative regulation of T cell cytokine production; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0032831; P:positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IBA:RefGenome.::GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.::GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IBA:RefGenome.::GO:0002851; P:positive regulation of peripheral T cell tolerance induction; IBA:RefGenome.::GO:0002669; P:positive regulation of T cell anergy; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0032914; P:positive regulation of transforming growth factor beta1 production; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0048302; P:regulation of isotype switching to IgG isotypes; IBA:RefGenome.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0043029; P:T cell homeostasis; NAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IBA:RefGenome.::GO:0002513; P:tolerance induction to self antigen; IBA:RefGenome. | 212 | Q3UM89 | 302 | FOXR2_MOUSE Forkhead box protein R2 OS=Mus mu... | 85 | 0.000002 | 53.9 | 33 | 59 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 213 | Q6U8D7 | 431 | FOXP3_MACFA Forkhead box protein P3 OS=Macaca... | 94 | 0.000003 | 54.7 | 31 | 60 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051525; F:NFAT protein binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.::GO:0032693; P:negative regulation of interleukin-10 production; ISS:UniProtKB.::GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; ISS:UniProtKB.::GO:0032703; P:negative regulation of interleukin-2 production; ISS:UniProtKB.::GO:0032713; P:negative regulation of interleukin-4 production; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0002725; P:negative regulation of T cell cytokine production; ISS:UniProtKB.::GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042110; P:T cell activation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 214 | Q9DBY0 | 795 | FOXP4_MOUSE Forkhead box protein P4 OS=Mus mu... | 93 | 0.000003 | 54.7 | 31 | 60 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048617; P:embryonic foregut morphogenesis; IMP:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 215 | B4G4S8 | 629 | FOXO_DROPE Forkhead box protein O OS=Drosophi... | 82 | 0.000004 | 54.7 | 39 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 216 | B3P0K6 | 615 | FOXO_DROER Forkhead box protein O OS=Drosophi... | 82 | 0.000004 | 54.3 | 39 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 217 | Q298W7 | 644 | FOXO_DROPS Forkhead box protein O OS=Drosophi... | 82 | 0.000004 | 54.3 | 39 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 218 | Q95V55 | 613 | FOXO_DROME Forkhead box protein O OS=Drosophi... | 82 | 0.000004 | 54.3 | 39 | 60 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; IMP:FlyBase.::GO:0009267; P:cellular response to starvation; IMP:FlyBase.::GO:0001745; P:compound eye morphogenesis; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0005977; P:glycogen metabolic process; IMP:FlyBase.::GO:0008286; P:insulin receptor signaling pathway; IGI:FlyBase.::GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:FlyBase.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:FlyBase.::GO:0040027; P:negative regulation of vulval development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0019216; P:regulation of lipid metabolic process; IMP:UniProtKB.::GO:0016241; P:regulation of macroautophagy; IMP:FlyBase.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009617; P:response to bacterium; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0009888; P:tissue development; IBA:RefGenome. | 219 | Q9R1E0 | 652 | FOXO1_MOUSE Forkhead box protein O1 OS=Mus mu... | 118 | 0.000004 | 54.3 | 32 | 53 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0001568; P:blood vessel development; IMP:MGI.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045722; P:positive regulation of gluconeogenesis; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 220 | B4PTD3 | 628 | FOXO_DROYA Forkhead box protein O OS=Drosophi... | 82 | 0.000004 | 54.3 | 39 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 221 | B4NFR1 | 628 | FOXO_DROWI Forkhead box protein O OS=Drosophi... | 82 | 0.000004 | 54.3 | 39 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 222 | B3LYS5 | 600 | FOXO_DROAN Forkhead box protein O OS=Drosophi... | 82 | 0.000005 | 54.3 | 39 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 223 | Q12778 | 655 | FOXO1_HUMAN Forkhead box protein O1 OS=Homo s... | 118 | 0.000005 | 54.3 | 32 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 224 | O16850 | 541 | FOXO_CAEEL Forkhead box protein O OS=Caenorha... | 160 | 0.000006 | 53.5 | 26 | 48 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0034605; P:cellular response to heat; IDA:UniProtKB.::GO:0008340; P:determination of adult lifespan; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0060537; P:muscle tissue development; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:UniProtKB.::GO:0002821; P:positive regulation of adaptive immune response; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0010564; P:regulation of cell cycle process; IEP:UniProtKB.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; IMP:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0046890; P:regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 225 | O43524 | 673 | FOXO3_HUMAN Forkhead box protein O3 OS=Homo s... | 71 | 0.000006 | 53.5 | 39 | 59 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0001547; P:antral ovarian follicle growth; IBA:RefGenome.::GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0006917; P:induction of apoptosis; IBA:RefGenome.::GO:0001544; P:initiation of primordial ovarian follicle growth; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0001556; P:oocyte maturation; IBA:RefGenome.::GO:0001542; P:ovulation from ovarian follicle; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006417; P:regulation of translation; IDA:UniProtKB.::GO:0009888; P:tissue development; IBA:RefGenome. | 226 | Q9WVH4 | 672 | FOXO3_MOUSE Forkhead box protein O3 OS=Mus mu... | 71 | 0.000009 | 53.1 | 39 | 59 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0001547; P:antral ovarian follicle growth; IMP:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IDA:MGI.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0006917; P:induction of apoptosis; IMP:MGI.::GO:0001544; P:initiation of primordial ovarian follicle growth; IMP:MGI.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0001556; P:oocyte maturation; IMP:MGI.::GO:0001542; P:ovulation from ovarian follicle; IMP:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045648; P:positive regulation of erythrocyte differentiation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006417; P:regulation of translation; ISS:UniProtKB.::GO:0009888; P:tissue development; IBA:RefGenome. | 227 | O88621 | 401 | FOXH1_MOUSE Forkhead box protein H1 OS=Mus mu... | 84 | 0.00001 | 52.4 | 33 | 57 | GO:0032444; C:activin responsive factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0070412; F:R-SMAD binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0048318; P:axial mesoderm development; IMP:MGI.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0042074; P:cell migration involved in gastrulation; IBA:RefGenome.::GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; IMP:MGI.::GO:0021508; P:floor plate formation; IBA:RefGenome.::GO:0001947; P:heart looping; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0010159; P:specification of organ position; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 228 | B4HF64 | 609 | FOXO_DROSE Forkhead box protein O OS=Drosophi... | 82 | 0.00001 | 52.4 | 38 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 229 | P70056 | 518 | FOXH1_XENLA Forkhead box protein H1 OS=Xenopu... | 80 | 0.00002 | 52.4 | 38 | 55 | GO:0032444; C:activin responsive factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0046332; F:SMAD binding; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0032924; P:activin receptor signaling pathway; IMP:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0007501; P:mesodermal cell fate specification; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 230 | Q6EUW2 | 631 | FOXO1_XENLA Forkhead box protein O1 OS=Xenopu... | 82 | 0.00003 | 51.6 | 38 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 231 | Q6EUW1 | 657 | FOXO3_XENLA Forkhead box protein O3 OS=Xenopu... | 82 | 0.00003 | 51.6 | 37 | 57 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 232 | Q66JJ0 | 626 | FOXO1_XENTR Forkhead box protein O1 OS=Xenopu... | 82 | 0.00003 | 51.2 | 38 | 59 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 233 | B4KBF6 | 563 | FOXO_DROMO Forkhead box protein O OS=Drosophi... | 82 | 0.00004 | 51.2 | 38 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 234 | A8MYZ6 | 492 | FOXO6_HUMAN Forkhead box protein O6 OS=Homo s... | 126 | 0.00005 | 50.4 | 30 | 52 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0016525; P:negative regulation of angiogenesis; IBA:RefGenome.::GO:0008285; P:negative regulation of cell proliferation; IBA:RefGenome.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 235 | B4MB78 | 609 | FOXO_DROVI Forkhead box protein O OS=Drosophi... | 82 | 0.00008 | 50.1 | 38 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 236 | Q70KY4 | 559 | FOXO6_MOUSE Forkhead box protein O6 OS=Mus mu... | 82 | 0.00008 | 50.1 | 38 | 57 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0016525; P:negative regulation of angiogenesis; IBA:RefGenome.::GO:0008285; P:negative regulation of cell proliferation; IBA:RefGenome.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 237 | B4JSC2 | 630 | FOXO_DROGR Forkhead box protein O OS=Drosophi... | 80 | 0.0001 | 49.3 | 38 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 238 | P98177 | 505 | FOXO4_HUMAN Forkhead box protein O4 OS=Homo s... | 81 | 0.0004 | 47.8 | 36 | 56 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000080; P:G1 phase of mitotic cell cycle; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IBA:RefGenome.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 239 | Q6PJQ5 | 311 | FOXR2_HUMAN Forkhead box protein R2 OS=Homo s... | 63 | 0.001 | 45.4 | 35 | 59 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 240 | Q9WVH3 | 505 | FOXO4_MOUSE Forkhead box protein O4 OS=Mus mu... | 81 | 0.002 | 45.4 | 35 | 56 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000080; P:G1 phase of mitotic cell cycle; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IDA:MGI.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 241 | Q19802 | 461 | FKH5_CAEEL Putative forkhead-related transcri... | 123 | 0.26 | 38.5 | 28 | 46 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009653; P:anatomical structure morphogenesis; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. |