Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR095C
Length:
1226
Number of sequences:
5887
Description:
YPR095C SYT1 SGDID:S000006299, Chr XVI from 724717-721037, Genome Release 64-1-1, reverse complement, Verified ORF, "Guanine nucleotide exchange factor (GEF) for Arf proteins; promotes activation of Arl1p, which recruits Imh1p to the Golgi; involved in vesicular transport; member of the Sec7-domain family; contains a PH domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06836    1226   SYT1_YEAST Arf guanine nucleotide exchange fa...12260     2528     100     100GO:0044431; C:Golgi apparatus part; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032014; P:positive regulation of ARF protein signal transduction; IMP:SGD.::GO:0016192; P:vesicle-mediated transport; IGI:SGD.
2O13817    1082   SEC7C_SCHPO Protein transport protein sec73 O...1716e-24     113     40     55GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006887; P:exocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
3Q10491    928   YDG1_SCHPO PH and SEC7 domain-containing prot...1470.000000000000001     85.9     34     51GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006887; P:exocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
4Q54KA7    986   SECG_DICDI Ankyrin repeat, PH and SEC7 domain...1480.0000000000003     78.6     33     55GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
5Q9P7V5    1822   SEC7B_SCHPO Protein transport protein sec72 O...1230.00000000002     72.8     34     54GO:0005938; C:cell cortex; IDA:PomBase.::GO:0000137; C:Golgi cis cisterna; IDA:PomBase.::GO:0000138; C:Golgi trans cisterna; IDA:PomBase.::GO:0005798; C:Golgi-associated vesicle; ISS:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005488; F:binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; ISS:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
6Q8R0S2    961   IQEC1_MOUSE IQ motif and SEC7 domain-containi...1490.00000000005     71.2     30     50GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
7Q6DN90    963   IQEC1_HUMAN IQ motif and SEC7 domain-containi...1490.00000000005     70.9     29     50GO:0030054; C:cell junction; IDA:HPA.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
8Q42510    1451   EMB30_ARATH Pattern formation protein EMB30 O...1480.00000000007     70.9     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0010292; F:GTP:GDP antiporter activity; IGI:TAIR.::GO:0042803; F:protein homodimerization activity; IPI:TAIR.
GO:0010540; P:basipetal auxin transport; IMP:TAIR.::GO:0007155; P:cell adhesion; IMP:TAIR.::GO:0007047; P:cellular cell wall organization; IMP:TAIR.::GO:0000911; P:cytokinesis by cell plate formation; IMP:TAIR.::GO:0010386; P:lateral root primordium development; IMP:TAIR.::GO:0009942; P:longitudinal axis specification; IMP:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0048209; P:regulation of vesicle targeting, to, from or within Golgi; TAS:TAIR.::GO:0009826; P:unidimensional cell growth; IMP:TAIR.
9Q3TES0    1195   IQEC3_MOUSE IQ motif and SEC7 domain-containi...1490.00000000009     70.5     29     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0060077; C:inhibitory synapse; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
10Q76M68    1194   IQEC3_RAT IQ motif and SEC7 domain-containing...1490.0000000001     70.1     29     50GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032857; P:activation of ARF GTPase activity; IDA:UniProtKB.
11Q9UPP2    1182   IQEC3_HUMAN IQ motif and SEC7 domain-containi...1490.0000000003     68.6     28     50GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
12Q5JU85    1478   IQEC2_HUMAN IQ motif and SEC7 domain-containi...1490.0000000004     68.2     27     52GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
13Q5DU25    1478   IQEC2_MOUSE IQ motif and SEC7 domain-containi...1490.0000000004     68.2     27     52GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
14Q9Y6D6    1849   BIG1_HUMAN Brefeldin A-inhibited guanine nucl...1480.000000005     64.7     28     49GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0017022; F:myosin binding; IPI:UniProtKB.
GO:0006887; P:exocytosis; TAS:ProtInc.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
15O46382    1849   BIG1_BOVIN Brefeldin A-inhibited guanine nucl...1480.000000005     64.7     28     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
16P97694    398   CYH1_RAT Cytohesin-1 OS=Rattus norvegicus (Ra...1630.000000006     63.2     32     49GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
17Q9QX11    398   CYH1_MOUSE Cytohesin-1 OS=Mus musculus (Mouse...1630.000000006     63.2     32     49GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005923; C:tight junction; IDA:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
18Q15438    398   CYH1_HUMAN Cytohesin-1 OS=Homo sapiens (Human...1630.000000007     63.2     32     49GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IDA:MGI.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
19Q76MZ1    398   CYH1_CHLAE Cytohesin-1 OS=Chlorocebus aethiop...1630.000000007     63.2     32     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
20P39993    1459   GEA2_YEAST ARF guanine-nucleotide exchange fa...1220.00000001     63.5     36     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000137; C:Golgi cis cisterna; IDA:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0030036; P:actin cytoskeleton organization; IGI:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IGI:SGD.::GO:0033363; P:secretory granule organization; IMP:SGD.
21Q9UT02    1811   SEC7A_SCHPO Protein transport protein sec71 O...1190.00000002     62.8     34     50GO:0005798; C:Golgi-associated vesicle; ISS:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005488; F:binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; ISS:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
22Q9Y6D5    1785   BIG2_HUMAN Brefeldin A-inhibited guanine nucl...1480.00000004     62     28     47GO:0005829; C:cytosol; IDA:MGI.::GO:0000139; C:Golgi membrane; IDA:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0006887; P:exocytosis; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
23P11075    2009   SEC7_YEAST Protein transport protein SEC7 OS=...1540.0000001     60.1     27     49GO:0005829; C:cytosol; IDA:SGD.::GO:0005798; C:Golgi-associated vesicle; IDA:SGD.::GO:0005770; C:late endosome; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0005488; F:binding; IEA:InterPro.
GO:0000045; P:autophagic vacuole assembly; IMP:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
24P47102    1408   GEA1_YEAST ARF guanine-nucleotide exchange fa...1630.0000002     59.3     31     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000137; C:Golgi cis cisterna; IDA:SGD.::GO:0005798; C:Golgi-associated vesicle; IPI:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0030036; P:actin cytoskeleton organization; IGI:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IGI:SGD.
25P34512    393   GRP1_CAEEL GTP exchange factor for ARFs 1 OS=...1150.0000007     56.6     30     52GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
26Q9UIA0    394   CYH4_HUMAN Cytohesin-4 OS=Homo sapiens (Human...1240.0000008     56.6     28     49GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
27Q80YW0    393   CYH4_MOUSE Cytohesin-4 OS=Mus musculus (Mouse...1440.0000008     56.6     29     48GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
28P97696    400   CYH3_RAT Cytohesin-3 OS=Rattus norvegicus (Ra...1410.000001     55.8     30     48GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
29O08967    399   CYH3_MOUSE Cytohesin-3 OS=Mus musculus (Mouse...1410.000001     55.8     30     48GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IPI:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0045785; P:positive regulation of cell adhesion; IDA:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
30O43739    400   CYH3_HUMAN Cytohesin-3 OS=Homo sapiens (Human...1410.000002     55.1     30     48GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; TAS:ProtInc.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; TAS:ProtInc.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
31Q2KI41    410   CYH2_BOVIN Cytohesin-2 OS=Bos taurus (Bovine)...1450.000003     55.1     30     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; ISS:RefGenome.
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