Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR066W
Length:
299
Number of sequences:
5887
Description:
YPR066W UBA3 SGDID:S000006270, Chr XVI from 681213-682112, Genome Release 64-1-1, Verified ORF, "Protein that acts together with Ula1p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q99344    299   UBA3_YEAST NEDD8-activating enzyme E1 catalyt...2990     615     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0045116; P:protein neddylation; IDA:SGD.
2Q5R4A0    463   UBA3_PONAB NEDD8-activating enzyme E1 catalyt...3142e-82     263     43     64
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0045116; P:protein neddylation; IEA:InterPro.
3Q8TBC4    463   UBA3_HUMAN NEDD8-activating enzyme E1 catalyt...3142e-82     262     43     64GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
GO:0045116; P:protein neddylation; IEA:InterPro.::GO:0006508; P:proteolysis; TAS:ProtInc.
4Q99MI7    462   UBA3_RAT NEDD8-activating enzyme E1 catalytic...3144e-82     261     43     64
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IMP:RGD.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.::GO:0045116; P:protein neddylation; TAS:RGD.
5Q8C878    462   UBA3_MOUSE NEDD8-activating enzyme E1 catalyt...3145e-82     261     43     64
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; TAS:MGI.
GO:0007113; P:endomitotic cell cycle; IMP:MGI.::GO:0045116; P:protein neddylation; IEA:InterPro.::GO:0051726; P:regulation of cell cycle; IMP:MGI.
6Q7ZVX6    462   UBA3_DANRE NEDD8-activating enzyme E1 catalyt...3075e-80     256     42     65
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0045116; P:protein neddylation; IEA:InterPro.
7Q09765    444   UBA3_SCHPO NEDD8-activating enzyme E1 catalyt...3215e-75     243     40     61GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0045116; P:protein neddylation; TAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
8Q54QG9    442   UBA3_DICDI NEDD8-activating enzyme E1 catalyt...3114e-70     230     39     60
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; ISS:dictyBase.
GO:0045116; P:protein neddylation; ISS:dictyBase.
9Q9V6U8    450   UBA3_DROME NEDD8-activating enzyme E1 catalyt...3061e-69     229     40     62GO:0043234; C:protein complex; IPI:FlyBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0045116; P:protein neddylation; IDA:FlyBase.
10Q19360    430   UBA3_CAEEL NEDD8-activating enzyme E1 catalyt...3102e-66     220     39     59GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0045116; P:protein neddylation; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
11O65041    454   UBA3_ARATH NEDD8-activating enzyme E1 catalyt...3072e-66     221     40     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; IDA:TAIR.::GO:0046982; F:protein heterodimerization activity; NAS:TAIR.
GO:0045116; P:protein neddylation; TAS:TAIR.
12P52488    636   UBA2_YEAST Ubiquitin-activating enzyme E1-lik...1991e-32     130     37     58GO:0031510; C:SUMO activating enzyme complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; IPI:SGD.
GO:0016925; P:protein sumoylation; IDA:SGD.
13Q7SXG4    650   SAE2_DANRE SUMO-activating enzyme subunit 2 O...2037e-31     125     39     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
14Q9Z1F9    638   SAE2_MOUSE SUMO-activating enzyme subunit 2 O...2349e-31     125     36     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:MGI.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
15Q9UBT2    640   SAE2_HUMAN SUMO-activating enzyme subunit 2 O...2341e-30     125     35     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0019948; F:SUMO activating enzyme activity; IDA:UniProtKB.
GO:0016925; P:protein sumoylation; IDA:UniProtKB.
16Q28GH3    641   SAE2_XENTR SUMO-activating enzyme subunit 2 O...2612e-29     122     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
17Q9NAN1    582   SAE2_CAEEL SUMO-activating enzyme subunit uba...1793e-29     120     39     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; IDA:WormBase.
GO:0009952; P:anterior/posterior pattern specification; IGI:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
18Q7ZY60    641   SAE2B_XENLA SUMO-activating enzyme subunit 2-...2612e-28     119     33     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
19Q642Q1    641   SAE2A_XENLA SUMO-activating enzyme subunit 2-...2612e-28     119     33     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
20Q54L40    661   SAE2_DICDI SUMO-activating enzyme subunit 2 O...1872e-26     113     39     57GO:0031510; C:SUMO activating enzyme complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:dictyBase.
GO:0016925; P:protein sumoylation; ISS:dictyBase.
21O31619    336   THIF_BACSU Sulfur carrier protein ThiS adenyl...1610.0000000000001     73.6     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
22O59954    482   UBA4_EMENI Adenylyltransferase and sulfurtran...1160.000000000001     71.2     36     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
23P38820    440   UBA4_YEAST Adenylyltransferase and sulfurtran...1600.0000000005     63.2     29     46GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070733; F:protein adenylyltransferase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004792; F:thiosulfate sulfurtransferase activity; IDA:SGD.::GO:0042292; F:URM1 activating enzyme activity; IDA:SGD.
GO:0007114; P:cell budding; IGI:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0018192; P:enzyme active site formation via L-cysteine persulfide; IMP:UniProtKB.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0032447; P:protein urmylation; IDA:SGD.::GO:2000220; P:regulation of pseudohyphal growth; IMP:SGD.::GO:0002143; P:tRNA wobble position uridine thiolation; IMP:SGD.
24B5VK45    440   UBA4_YEAS6 Adenylyltransferase and sulfurtran...1600.0000000005     63.2     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
25B3LSM6    440   UBA4_YEAS1 Adenylyltransferase and sulfurtran...1600.0000000005     63.2     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
26A2R3H4    482   UBA4_ASPNC Adenylyltransferase and sulfurtran...1150.0000000007     63.2     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
27B0W377    438   MOCS3_CULQU Adenylyltransferase and sulfurtra...1500.0000000009     62.8     29     45GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
28A6ZT19    440   UBA4_YEAS7 Adenylyltransferase and sulfurtran...1600.000000001     62.4     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
29A1CAZ7    492   UBA4_ASPCL Adenylyltransferase and sulfurtran...1150.000000001     62.4     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
30O44510    402   MOCS3_CAEEL Adenylyltransferase and sulfurtra...1570.000000002     61.6     28     45GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004792; F:thiosulfate sulfurtransferase activity; ISS:UniProtKB.
GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; ISS:UniProtKB.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
31A5DMB6    424   UBA4_PICGU Adenylyltransferase and sulfurtran...1520.000000003     60.8     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
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