Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR065W
Length:
368
Number of sequences:
5887
Description:
YPR065W ROX1 SGDID:S000006269, Chr XVI from 679693-680799, Genome Release 64-1-1, Verified ORF, "Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P48434    494   SOX9_CHICK Transcription factor SOX-9 OS=Gall...1060.0000002     56.2     29     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0003170; P:heart valve development; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92P48435    396   SOX11_CHICK Transcription factor SOX-11 OS=Ga...880.0000002     55.8     35     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93B3DLD3    362   SOX18_XENTR Transcription factor Sox-18 OS=Xe...920.0000002     55.8     35     58GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0007507; P:heart development; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
94Q8AWH2    376   S17B1_XENTR Transcription factor Sox-17-beta....910.0000002     55.8     34     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
95P55863    309   SOX3A_XENLA Transcription factor Sox-3-A OS=X...800.0000002     55.5     35     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0001704; P:formation of primary germ layer; IMP:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
96Q6F2F0    376   S17B3_XENTR Transcription factor Sox-17-beta....910.0000002     55.8     34     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
97Q9UN79    622   SOX13_HUMAN Transcription factor SOX-13 OS=Ho...1340.0000003     56.2     30     53GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
98Q69FB1    229   SRY_BUBBU Sex-determining region Y protein OS...930.0000003     54.3     40     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
99P57074    470   SOX8_CHICK Transcription factor SOX-8 OS=Gall...880.0000003     55.5     32     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0003170; P:heart valve development; IEP:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
100Q864Q4    216   SRY_MESST Sex-determining region Y protein OS...930.0000004     53.5     35     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
101Q02991    343   MAT2_COCHE Mating-type protein MAT-2 OS=Cochl...800.0000004     54.7     39     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
102Q9P445    337   MAT2_COCSA Mating-type protein MAT-2 OS=Cochl...800.0000004     54.7     39     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
103P48432    319   SOX2_MOUSE Transcription factor SOX-2 OS=Mus ...880.0000005     54.7     34     59GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0021984; P:adenohypophysis development; IMP:MGI.::GO:0001708; P:cell fate specification; IMP:MGI.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0050973; P:detection of mechanical stimulus involved in equilibrioception; IMP:MGI.::GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IMP:MGI.::GO:0048852; P:diencephalon morphogenesis; IMP:MGI.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IDA:MGI.::GO:0021879; P:forebrain neuron differentiation; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0060235; P:lens induction in camera-type eye; IGI:MGI.::GO:0048286; P:lung alveolus development; IDA:MGI.::GO:0030539; P:male genitalia development; IMP:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.::GO:0045668; P:negative regulation of osteoblast differentiation; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0048663; P:neuron fate commitment; IMP:MGI.::GO:0097150; P:neuronal stem cell maintenance; IGI:UniProtKB.::GO:0030910; P:olfactory placode formation; IGI:MGI.::GO:0046148; P:pigment biosynthetic process; IMP:MGI.::GO:0030858; P:positive regulation of epithelial cell differentiation; IDA:MGI.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:MGI.::GO:0043586; P:tongue development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
104P40637    72   AES1_ALLMI SRY-related protein AES1 OS=Alliga...770.0000005     51.2     36     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
105Q9XT60    220   SRY_CANFA Sex-determining region Y protein OS...900.0000005     53.5     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106P40639    72   AES4_ALLMI SRY-related protein AES4 OS=Alliga...770.0000006     51.2     36     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
107P40655    71   LG28_EUBMA SRY-related protein LG28 OS=Eublep...770.0000006     51.2     36     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
108P40651    72   MG42_TARMA SRY-related protein MG42 OS=Tarent...770.0000006     51.2     35     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
109Q9W7R6    240   SOX14_CHICK Transcription factor SOX-14 OS=Ga...820.0000006     53.5     35     59GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
110A4QNG3    239   SOX14_XENTR Transcription factor Sox-14 OS=Xe...820.0000006     53.5     37     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111Q32PP9    238   SOX14_DANRE Transcription factor Sox-14 OS=Da...820.0000007     53.5     37     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0021854; P:hypothalamus development; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
112B0ZTE2    239   SOX14_XENLA Transcription factor Sox-14 OS=Xe...820.0000008     53.1     37     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
113Q04892    240   SOX14_MOUSE Transcription factor SOX-14 OS=Mu...820.0000008     53.1     35     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
114Q6TC30    221   SRY_ERIBA Sex-determining region Y protein OS...940.0000008     52.8     36     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
115Q6NVN0    311   SOX2_XENTR Transcription factor Sox-2 OS=Xeno...830.0000008     53.9     34     59GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
116P61259    240   SOX14_MACFA Transcription factor SOX-14 OS=Ma...820.0000008     53.1     35     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117O95416    240   SOX14_HUMAN Transcription factor SOX-14 OS=Ho...820.0000008     53.1     35     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007399; P:nervous system development; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118Q28778    204   SRY_PANPA Sex-determining region Y protein OS...860.0000008     52.4     37     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119O42569    311   SOX2_XENLA Transcription factor Sox-2 OS=Xeno...830.0000009     53.5     34     59GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
120Q864Q2    196   SRY_PHOPH Sex-determining region Y protein OS...910.0000009     52.4     35     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121Q864Q1    196   SRY_NEOPH Sex-determining region Y protein OS...910.0000009     52.4     35     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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