| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P48430 | 315 | SOX2_CHICK Transcription factor SOX-2 OS=Gall... | 90 | 0.0000001 | 56.6 | 34 | 59 | | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 62 | Q9BG91 | 509 | SOX9_CALJA Transcription factor SOX-9 OS=Call... | 98 | 0.0000001 | 57 | 32 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 63 | Q864Q5 | 216 | SRY_KOGSI Sex-determining region Y protein OS... | 96 | 0.0000001 | 55.5 | 36 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 64 | Q06945 | 474 | SOX4_HUMAN Transcription factor SOX-4 OS=Homo... | 82 | 0.0000001 | 57 | 39 | 62 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB. | | | | | | | | | | GO:0035910; P:ascending aorta morphogenesis; ISS:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; ISS:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.::GO:0021782; P:glial cell development; ISS:UniProtKB.::GO:0014009; P:glial cell proliferation; ISS:UniProtKB.::GO:0060993; P:kidney morphogenesis; ISS:BHF-UCL.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; ISS:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0001841; P:neural tube formation; ISS:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; IMP:UniProtKB.::GO:0002328; P:pro-B cell differentiation; ISS:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; ISS:UniProtKB.::GO:0021522; P:spinal cord motor neuron differentiation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL. | 65 | P48046 | 204 | SRY_GORGO Sex-determining region Y protein OS... | 87 | 0.0000001 | 55.1 | 39 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 66 | Q863C2 | 229 | SRY_AXIPR Sex-determining region Y protein OS... | 96 | 0.0000001 | 55.5 | 36 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 67 | P51501 | 227 | SRY_CALJA Sex-determining region Y protein OS... | 86 | 0.0000001 | 55.5 | 40 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 68 | Q04887 | 507 | SOX9_MOUSE Transcription factor SOX-9 OS=Mus ... | 98 | 0.0000001 | 57 | 31 | 55 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:MGI.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0004672; F:protein kinase activity; IMP:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0060018; P:astrocyte fate commitment; IGI:MGI.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.::GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; IMP:MGI.::GO:0001708; P:cell fate specification; IMP:MGI.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0071504; P:cellular response to heparin; IDA:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IDA:MGI.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; IMP:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0003203; P:endocardial cushion morphogenesis; IMP:MGI.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; IMP:MGI.::GO:0001837; P:epithelial to mesenchymal transition; IMP:MGI.::GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0001942; P:hair follicle development; IMP:MGI.::GO:0003188; P:heart valve formation; IMP:MGI.::GO:0060729; P:intestinal epithelial structure maintenance; IMP:MGI.::GO:0035622; P:intrahepatic bile duct development; IMP:MGI.::GO:0060174; P:limb bud formation; IEP:UniProtKB.::GO:0019100; P:male germ-line sex determination; IMP:MGI.::GO:0030879; P:mammary gland development; IEP:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; IMP:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; IMP:MGI.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0002683; P:negative regulation of immune system process; IMP:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; IDA:MGI.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:MGI.::GO:0030903; P:notochord development; IEP:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0001503; P:ossification; IEP:UniProtKB.::GO:0030916; P:otic vesicle formation; IMP:MGI.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:MGI.::GO:2000138; P:positive regulation of cell proliferation involved in heart morphogenesis; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; IMP:MGI.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IMP:MGI.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; IMP:MGI.::GO:0072034; P:renal vesicle induction; IMP:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; IGI:MGI.::GO:0060009; P:Sertoli cell development; IGI:MGI.::GO:0035019; P:somatic stem cell maintenance; IMP:MGI.::GO:0007283; P:spermatogenesis; IGI:MGI.::GO:0072197; P:ureter morphogenesis; IGI:MGI.::GO:0072190; P:ureter urothelium development; IEP:UniProtKB. | 69 | Q6DFF5 | 476 | SOX9B_XENLA Transcription factor Sox-9-B OS=X... | 86 | 0.0000001 | 57 | 33 | 58 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; ISS:UniProtKB. | | | | | | | | | | GO:0051216; P:cartilage development; ISS:UniProtKB.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0014029; P:neural crest formation; ISS:UniProtKB.::GO:0043049; P:otic placode formation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 70 | B7ZR65 | 477 | SOX9A_XENLA Transcription factor Sox-9-A OS=X... | 101 | 0.0000001 | 57 | 31 | 56 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0051216; P:cartilage development; ISS:UniProtKB.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0014029; P:neural crest formation; IMP:UniProtKB.::GO:0043049; P:otic placode formation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 71 | Q7YRJ7 | 513 | SOX9_CANFA Transcription factor SOX-9 OS=Cani... | 98 | 0.0000001 | 57 | 32 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 72 | O18896 | 509 | SOX9_PIG Transcription factor SOX-9 OS=Sus sc... | 98 | 0.0000001 | 57 | 31 | 55 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 73 | Q05066 | 204 | SRY_HUMAN Sex-determining region Y protein OS... | 87 | 0.0000001 | 55.1 | 39 | 55 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; NAS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW. | 74 | A5D8R3 | 373 | S17B3_XENLA Transcription factor Sox-17-beta.... | 91 | 0.0000001 | 56.6 | 34 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 75 | Q04886 | 464 | SOX8_MOUSE Transcription factor SOX-8 OS=Mus ... | 86 | 0.0000001 | 56.6 | 33 | 58 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; IMP:MGI.::GO:0060018; P:astrocyte fate commitment; IGI:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0048484; P:enteric nervous system development; IMP:UniProtKB.::GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0072289; P:metanephric nephron tubule formation; IGI:MGI.::GO:0061138; P:morphogenesis of a branching epithelium; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; IDA:MGI.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0007422; P:peripheral nervous system development; IGI:MGI.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0014015; P:positive regulation of gliogenesis; IMP:UniProtKB.::GO:0033690; P:positive regulation of osteoblast proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0010817; P:regulation of hormone levels; IMP:MGI.::GO:0072034; P:renal vesicle induction; IMP:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; IGI:MGI.::GO:0060009; P:Sertoli cell development; IEP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB.::GO:0007283; P:spermatogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0072197; P:ureter morphogenesis; IGI:MGI. | 76 | Q864Q7 | 204 | SRY_EUBAS Sex-determining region Y protein OS... | 96 | 0.0000001 | 54.7 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 77 | P35716 | 441 | SOX11_HUMAN Transcription factor SOX-11 OS=Ho... | 88 | 0.0000001 | 56.6 | 35 | 63 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB.::GO:0008135; F:translation factor activity, nucleic acid binding; IDA:UniProtKB. | | | | | | | | | | GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.::GO:0061386; P:closure of optic fissure; ISS:UniProtKB.::GO:0061303; P:cornea development in camera-type eye; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.::GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.::GO:0014009; P:glial cell proliferation; ISS:UniProtKB.::GO:0060022; P:hard palate development; ISS:UniProtKB.::GO:0002089; P:lens morphogenesis in camera-type eye; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0060425; P:lung morphogenesis; ISS:UniProtKB.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0060253; P:negative regulation of glial cell proliferation; IMP:UniProtKB.::GO:0050672; P:negative regulation of lymphocyte proliferation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0001841; P:neural tube formation; ISS:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0035332; P:positive regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0046887; P:positive regulation of hormone secretion; ISS:UniProtKB.::GO:2001111; P:positive regulation of lens epithelial cell proliferation; ISS:UniProtKB.::GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IMP:UniProtKB.::GO:0045778; P:positive regulation of ossification; IMP:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.::GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IEP:UniProtKB.::GO:0072404; P:signal transduction involved in G1/S transition checkpoint; IEP:UniProtKB.::GO:0060023; P:soft palate development; ISS:UniProtKB.::GO:0061053; P:somite development; ISS:UniProtKB.::GO:0021510; P:spinal cord development; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0060412; P:ventricular septum morphogenesis; ISS:UniProtKB. | 78 | Q6TC38 | 218 | SRY_MIRLE Sex-determining region Y protein OS... | 85 | 0.0000002 | 55.1 | 38 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 79 | Q6TC39 | 218 | SRY_MIRAN Sex-determining region Y protein OS... | 85 | 0.0000002 | 55.1 | 38 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 80 | O42601 | 373 | S17B1_XENLA Transcription factor Sox-17-beta.... | 91 | 0.0000002 | 56.2 | 34 | 58 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0007492; P:endoderm development; IMP:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007494; P:midgut development; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IGI:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 81 | Q7M6Y2 | 395 | SOX11_MOUSE Transcription factor SOX-11 OS=Mu... | 88 | 0.0000002 | 56.2 | 35 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0008135; F:translation factor activity, nucleic acid binding; ISS:UniProtKB. | | | | | | | | | | GO:0003211; P:cardiac ventricle formation; IMP:UniProtKB.::GO:0061386; P:closure of optic fissure; IMP:UniProtKB.::GO:0061303; P:cornea development in camera-type eye; IMP:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:UniProtKB.::GO:0048704; P:embryonic skeletal system morphogenesis; IMP:UniProtKB.::GO:0061029; P:eyelid development in camera-type eye; IMP:UniProtKB.::GO:0014009; P:glial cell proliferation; IMP:UniProtKB.::GO:0060022; P:hard palate development; IMP:UniProtKB.::GO:0002089; P:lens morphogenesis in camera-type eye; IMP:UniProtKB.::GO:0060174; P:limb bud formation; IMP:UniProtKB.::GO:0060425; P:lung morphogenesis; IMP:UniProtKB.::GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.::GO:0060253; P:negative regulation of glial cell proliferation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0001841; P:neural tube formation; IMP:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; IMP:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; IMP:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:UniProtKB.::GO:0035332; P:positive regulation of hippo signaling cascade; IMP:UniProtKB.::GO:0046887; P:positive regulation of hormone secretion; IMP:UniProtKB.::GO:2001111; P:positive regulation of lens epithelial cell proliferation; IMP:UniProtKB.::GO:0050769; P:positive regulation of neurogenesis; IDA:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IDA:UniProtKB.::GO:0045778; P:positive regulation of ossification; IMP:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; ISS:UniProtKB.::GO:0060023; P:soft palate development; IMP:UniProtKB.::GO:0061053; P:somite development; IMP:UniProtKB.::GO:0021510; P:spinal cord development; IMP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB.::GO:0060412; P:ventricular septum morphogenesis; IMP:UniProtKB. | 82 | P0C1G9 | 395 | SOX11_RAT Transcription factor SOX-11 OS=Ratt... | 88 | 0.0000002 | 56.2 | 35 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0008135; F:translation factor activity, nucleic acid binding; ISS:UniProtKB. | | | | | | | | | | GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.::GO:0061386; P:closure of optic fissure; ISS:UniProtKB.::GO:0061303; P:cornea development in camera-type eye; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.::GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.::GO:0014009; P:glial cell proliferation; ISS:UniProtKB.::GO:0060022; P:hard palate development; ISS:UniProtKB.::GO:0001822; P:kidney development; IEP:RGD.::GO:0002089; P:lens morphogenesis in camera-type eye; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0060425; P:lung morphogenesis; ISS:UniProtKB.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0060253; P:negative regulation of glial cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IMP:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0001841; P:neural tube formation; ISS:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0014003; P:oligodendrocyte development; IEP:RGD.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0035332; P:positive regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0046887; P:positive regulation of hormone secretion; ISS:UniProtKB.::GO:2001111; P:positive regulation of lens epithelial cell proliferation; ISS:UniProtKB.::GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0045778; P:positive regulation of ossification; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; ISS:UniProtKB.::GO:0060023; P:soft palate development; ISS:UniProtKB.::GO:0061053; P:somite development; ISS:UniProtKB.::GO:0021510; P:spinal cord development; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0060412; P:ventricular septum morphogenesis; ISS:UniProtKB. | 83 | Q9BG89 | 509 | SOX9_PANTR Transcription factor SOX-9 OS=Pan ... | 98 | 0.0000002 | 56.6 | 32 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 84 | P57073 | 446 | SOX8_HUMAN Transcription factor SOX-8 OS=Homo... | 88 | 0.0000002 | 56.2 | 32 | 58 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; ISS:UniProtKB.::GO:0048484; P:enteric nervous system development; ISS:UniProtKB.::GO:0045444; P:fat cell differentiation; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0061138; P:morphogenesis of a branching epithelium; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001755; P:neural crest cell migration; ISS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.::GO:0007422; P:peripheral nervous system development; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0014015; P:positive regulation of gliogenesis; ISS:UniProtKB.::GO:0033690; P:positive regulation of osteoblast proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0010817; P:regulation of hormone levels; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060009; P:Sertoli cell development; ISS:UniProtKB.::GO:0007165; P:signal transduction; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0072197; P:ureter morphogenesis; ISS:UniProtKB. | 85 | Q9DDD7 | 292 | SX19B_DANRE Transcription factor Sox-19b OS=D... | 83 | 0.0000002 | 55.8 | 37 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 86 | Q90ZH7 | 361 | SX18B_XENLA Transcription factor Sox-18B OS=X... | 92 | 0.0000002 | 55.8 | 35 | 58 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0007507; P:heart development; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 87 | Q6VVD7 | 459 | SOX8_XENLA Transcription factor Sox-8 OS=Xeno... | 88 | 0.0000002 | 56.2 | 32 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014029; P:neural crest formation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 88 | P48431 | 317 | SOX2_HUMAN Transcription factor SOX-2 OS=Homo... | 90 | 0.0000002 | 55.8 | 34 | 59 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; TAS:BHF-UCL. | | | | | | | | | | GO:0035198; F:miRNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0006325; P:chromatin organization; NAS:UniProtKB.::GO:0001714; P:endodermal cell fate specification; IDA:MGI.::GO:0021781; P:glial cell fate commitment; NAS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0097150; P:neuronal stem cell maintenance; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0070848; P:response to growth factor stimulus; IDA:UniProtKB.::GO:0009611; P:response to wounding; IEP:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 89 | P54231 | 320 | SOX2_SHEEP Transcription factor SOX-2 OS=Ovis... | 90 | 0.0000002 | 55.8 | 34 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL. | | | | | | | | | | GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0097150; P:neuronal stem cell maintenance; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 90 | Q90ZH8 | 363 | SX18A_XENLA Transcription factor Sox-18A OS=X... | 92 | 0.0000002 | 55.8 | 35 | 58 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 91 | P48434 | 494 | SOX9_CHICK Transcription factor SOX-9 OS=Gall... | 106 | 0.0000002 | 56.2 | 29 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0003170; P:heart valve development; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
