Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR065W
Length:
368
Number of sequences:
5887
Description:
YPR065W ROX1 SGDID:S000006269, Chr XVI from 679693-680799, Genome Release 64-1-1, Verified ORF, "Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31A5A763    469   SOX10_PIG Transcription factor SOX-10 OS=Sus ...880.00000002     59.3     34     58GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
32P56693    466   SOX10_HUMAN Transcription factor SOX-10 OS=Ho...880.00000002     59.3     34     58GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
33Q864Q9    204   SRY_BALPH Sex-determining region Y protein OS...960.00000002     57.4     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34Q04888    466   SOX10_MOUSE Transcription factor SOX-10 OS=Mu...880.00000002     59.3     34     58GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0048469; P:cell maturation; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0048546; P:digestive tract morphogenesis; IMP:MGI.::GO:0048484; P:enteric nervous system development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0030318; P:melanocyte differentiation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0007422; P:peripheral nervous system development; IGI:MGI.::GO:0014015; P:positive regulation of gliogenesis; IMP:UniProtKB.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
35Q864Q8    204   SRY_MEGNO Sex-determining region Y protein OS...960.00000002     57     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
36B3DM43    753   SOX5_XENTR Transcription factor Sox-5 OS=Xeno...830.00000003     59.3     41     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37Q08143    288   SMR2_PODAS Sporulation minus regulator 2 OS=P...1030.00000003     58.2     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007338; P:single fertilization; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38P36389    223   SRY_HORSE Sex-determining region Y protein OS...840.00000003     57     36     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
39Q864R1    204   SRY_BALBN Sex-determining region Y protein OS...960.00000004     56.2     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40Q864R2    204   SRY_BALAC Sex-determining region Y protein OS...960.00000004     56.2     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41Q91731    382   SX11A_XENLA Transcription factor Sox-11-A OS=...880.00000004     58.2     36     61GO:0005634; C:nucleus; IC:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42Q28447    204   SRY_HYLLA Sex-determining region Y protein OS...870.00000004     56.2     39     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43P47792    297   SX19A_DANRE Transcription factor Sox-19a OS=D...830.00000004     57.8     39     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44Q9BH08    229   SRY_CERNI Sex-determining region Y protein OS...1540.00000004     56.6     32     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45Q864R0    204   SRY_BALMU Sex-determining region Y protein OS...960.00000004     56.2     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q6F2E7    482   SOX9_XENTR Transcription factor Sox-9 OS=Xeno...1080.00000004     58.2     30     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; ISS:UniProtKB.
GO:0051216; P:cartilage development; IEP:UniProtKB.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0014029; P:neural crest formation; ISS:UniProtKB.::GO:0043049; P:otic placode formation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47P40650    374   SX11B_XENLA Transcription factor Sox-11-B OS=...880.00000005     57.8     36     61GO:0005634; C:nucleus; IC:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48Q863D9    229   SRY_ALCAC Sex-determining region Y protein OS...960.00000005     56.6     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49P40652    72   MG43_TARMA SRY-related protein MG43 OS=Tarent...770.00000005     54.3     35     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
50Q66JF1    383   SOX11_XENTR Transcription factor Sox-11 OS=Xe...880.00000005     57.8     36     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51Q6P0E1    315   SOX2_DANRE Transcription factor Sox-2 OS=Dani...900.00000006     57.4     37     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IC:ZFIN.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0048592; P:eye morphogenesis; IMP:ZFIN.::GO:0031101; P:fin regeneration; IMP:ZFIN.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52O60248    233   SOX15_HUMAN Protein SOX-15 OS=Homo sapiens (H...830.00000006     56.6     39     58GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006325; P:chromatin organization; NAS:UniProtKB.::GO:0008584; P:male gonad development; TAS:ProtInc.
53Q06831    440   SOX4_MOUSE Transcription factor SOX-4 OS=Mus ...820.00000006     57.8     39     62GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.
GO:0035910; P:ascending aorta morphogenesis; IMP:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; IMP:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; IMP:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IMP:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; ISS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0021782; P:glial cell development; IMP:UniProtKB.::GO:0014009; P:glial cell proliferation; IMP:UniProtKB.::GO:0060993; P:kidney morphogenesis; IMP:BHF-UCL.::GO:0060174; P:limb bud formation; IMP:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0001841; P:neural tube formation; IMP:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; IMP:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0002328; P:pro-B cell differentiation; IMP:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; IMP:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IMP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; IMP:BHF-UCL.
54Q6IZ48    462   SOX8_TETNG Transcription factor Sox-8 OS=nigr...860.00000006     57.8     33     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q04891    613   SOX13_MOUSE Transcription factor SOX-13 OS=Mu...1330.00000008     57.4     29     52GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56Q863B7    229   SRY_ELADA Sex-determining region Y protein OS...960.00000009     55.8     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57Q28783    233   SRY_PONPY Sex-determining region Y protein OS...980.00000009     55.8     39     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58P61754    509   SOX9_PONPY Transcription factor SOX-9 OS=Pong...980.0000001     57     32     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
59P61753    509   SOX9_MACMU Transcription factor SOX-9 OS=Maca...980.0000001     57     32     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
60P48436    509   SOX9_HUMAN Transcription factor SOX-9 OS=Homo...980.0000001     57     32     56GO:0016585; C:chromatin remodeling complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; IDA:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; IMP:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; IDA:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006334; P:nucleosome assembly; IDA:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; IEP:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; IDA:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.::GO:0010564; P:regulation of cell cycle process; IMP:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
61P48430    315   SOX2_CHICK Transcription factor SOX-2 OS=Gall...900.0000001     56.6     34     59
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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