rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P25042 | 368 | ROX1_YEAST Repressor ROX1 OS=Saccharomyces ce... | 368 | 0 | 734 | 100 | 100 | GO:0000790; C:nuclear chromatin; IC:SGD. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:SGD.::GO:0001135; F:RNA polymerase II transcription factor recruiting transcription factor activity; IMP:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD. | | | | | | | | | | GO:0097201; P:negative regulation of transcription from RNA polymerase II promoter in response to stress; IMP:SGD. | 2 | O15370 | 315 | SOX12_HUMAN Transcription factor SOX-12 OS=Ho... | 82 | 0.000000000009 | 68.9 | 41 | 63 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0045165; P:cell fate commitment; IEP:UniProtKB.::GO:0021510; P:spinal cord development; ISS:UniProtKB. | 3 | Q04890 | 314 | SOX12_MOUSE Transcription factor SOX-12 OS=Mu... | 82 | 0.00000000001 | 68.6 | 41 | 63 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032993; C:protein-DNA complex; IDA:UniProtKB. | | | | | | | | | | GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0065004; P:protein-DNA complex assembly; IDA:UniProtKB.::GO:0021510; P:spinal cord development; IDA:UniProtKB. | 4 | B1H349 | 777 | SOX6_XENTR Transcription factor Sox-6 OS=Xeno... | 114 | 0.0000000005 | 64.7 | 37 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q28GD5 | 362 | SOX7_XENTR Transcription factor Sox-7 OS=Xeno... | 95 | 0.0000000006 | 63.9 | 36 | 57 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0001706; P:endoderm formation; ISS:UniProtKB.::GO:0007507; P:heart development; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0048793; P:pronephros development; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | O42342 | 362 | SOX7_XENLA Transcription factor Sox-7 OS=Xeno... | 95 | 0.0000000006 | 63.9 | 36 | 57 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001706; P:endoderm formation; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | P40646 | 380 | SOX7_MOUSE Transcription factor SOX-7 OS=Mus ... | 95 | 0.0000000006 | 63.9 | 38 | 58 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI. | 8 | Q5RCU4 | 787 | SOX6_PONAB Transcription factor SOX-6 OS=Pong... | 114 | 0.0000000007 | 64.3 | 37 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | P40645 | 827 | SOX6_MOUSE Transcription factor SOX-6 OS=Mus ... | 114 | 0.0000000008 | 63.9 | 37 | 57 | GO:0005667; C:transcription factor complex; IC:MGI. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI. | | | | | | | | | | GO:0035051; P:cardiac cell differentiation; IDA:MGI.::GO:0051216; P:cartilage development; IGI:MGI.::GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0048821; P:erythrocyte development; IMP:MGI.::GO:0016458; P:gene silencing; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0042692; P:muscle cell differentiation; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021778; P:oligodendrocyte cell fate specification; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | P35712 | 828 | SOX6_HUMAN Transcription factor SOX-6 OS=Homo... | 114 | 0.0000000009 | 63.9 | 37 | 57 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0007517; P:muscle organ development; NAS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q8AXQ4 | 244 | SOX12_XENLA Transcription factor Sox-12 OS=Xe... | 93 | 0.000000001 | 61.6 | 38 | 58 | GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | P40634 | 72 | ADW2_ALLMI SRY-related protein ADW2 OS=Alliga... | 77 | 0.000000001 | 58.5 | 38 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 13 | Q9BT81 | 388 | SOX7_HUMAN Transcription factor SOX-7 OS=Homo... | 95 | 0.000000002 | 62.4 | 37 | 57 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL. | | | | | | | | | | GO:0001706; P:endoderm formation; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | P40636 | 72 | ADW5_ALLMI SRY-related protein ADW5 OS=Alliga... | 77 | 0.000000003 | 57.4 | 38 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | P0CY17 | 181 | MTMC3_SCHPO Silenced mating-type M-specific p... | 90 | 0.000000005 | 58.9 | 37 | 60 | | | | | | | | | | | GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; NAS:PomBase. | | | | | | | | | | GO:0000747; P:conjugation with cellular fusion; NAS:PomBase.::GO:0007531; P:mating type determination; NAS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | P0CY16 | 181 | MATMC_SCHPO Mating-type M-specific polypeptid... | 90 | 0.000000005 | 58.9 | 37 | 60 | GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; NAS:PomBase. | | | | | | | | | | GO:0000747; P:conjugation with cellular fusion; NAS:PomBase.::GO:0007531; P:mating type determination; NAS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | C7U331 | 181 | MATMC_SCHPM Mating-type M-specific polypeptid... | 90 | 0.000000005 | 58.9 | 37 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | P40657 | 784 | SOX15_DROME Putative transcription factor SOX... | 98 | 0.000000006 | 61.6 | 31 | 59 | GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:FlyBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase. | 19 | P43267 | 231 | SOX15_MOUSE Protein SOX-15 OS=Mus musculus (M... | 83 | 0.000000007 | 59.3 | 41 | 58 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0048627; P:myoblast development; IMP:MGI.::GO:0045843; P:negative regulation of striated muscle tissue development; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0043403; P:skeletal muscle tissue regeneration; IMP:MGI. | 20 | Q6WRX6 | 181 | MATMC_SCHKA Mating-type M-specific polypeptid... | 89 | 0.000000008 | 58.2 | 37 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | P36393 | 208 | SRY_PIG Sex-determining region Y protein OS=S... | 96 | 0.000000009 | 58.5 | 36 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q9BG90 | 204 | SRY_MACMU Sex-determining region Y protein OS... | 87 | 0.00000001 | 58.2 | 41 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | P40635 | 72 | ADW4_ALLMI SRY-related protein ADW4 OS=Alliga... | 77 | 0.00000001 | 55.8 | 38 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | Q9W757 | 461 | SOX10_CHICK Transcription factor SOX-10 OS=Ga... | 88 | 0.00000001 | 59.7 | 34 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0060959; P:cardiac neuron development; IEP:UniProtKB. | 25 | Q8AXX8 | 446 | SOX10_XENLA Transcription factor Sox-10 OS=Xe... | 88 | 0.00000001 | 59.7 | 34 | 58 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032183; F:SUMO binding; IPI:UniProtKB. | | | | | | | | | | GO:0030318; P:melanocyte differentiation; IMP:UniProtKB.::GO:0014029; P:neural crest formation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 26 | P40647 | 757 | SOX5_XENLA Transcription factor Sox-5 OS=Xeno... | 115 | 0.00000002 | 59.7 | 36 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | P35710 | 763 | SOX5_MOUSE Transcription factor SOX-5 OS=Mus ... | 140 | 0.00000002 | 59.7 | 31 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI. | | | | | | | | | | GO:0051216; P:cartilage development; IGI:MGI.::GO:0045165; P:cell fate commitment; IGI:MGI.::GO:0021953; P:central nervous system neuron differentiation; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0060164; P:regulation of timing of neuron differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | P35711 | 763 | SOX5_HUMAN Transcription factor SOX-5 OS=Homo... | 140 | 0.00000002 | 59.7 | 31 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 29 | O55170 | 466 | SOX10_RAT Transcription factor SOX-10 OS=Ratt... | 88 | 0.00000002 | 59.3 | 34 | 58 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0048863; P:stem cell differentiation; IEP:RGD. | 30 | A4IIJ8 | 436 | SOX10_XENTR Transcription factor Sox-10 OS=Xe... | 88 | 0.00000002 | 59.3 | 34 | 58 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0032183; F:SUMO binding; ISS:UniProtKB. | | | | | | | | | | GO:0030318; P:melanocyte differentiation; ISS:UniProtKB.::GO:0014029; P:neural crest formation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 31 | A5A763 | 469 | SOX10_PIG Transcription factor SOX-10 OS=Sus ... | 88 | 0.00000002 | 59.3 | 34 | 58 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |