Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR054W
Length:
388
Number of sequences:
5887
Description:
YPR054W SMK1 SGDID:S000006258, Chr XVI from 666280-667446, Genome Release 64-1-1, Verified ORF, "Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q2NL51    490   GSK3A_MOUSE Glycogen synthase kinase-3 alpha ...3337e-40     152     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0003214; P:cardiac left ventricle morphogenesis; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0071285; P:cellular response to lithium ion; IDA:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IDA:BHF-UCL.::GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; IMP:BHF-UCL.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; IMP:BHF-UCL.::GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:BHF-UCL.::GO:2000467; P:positive regulation of glycogen (starch) synthase activity; IMP:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0003073; P:regulation of systemic arterial blood pressure; IMP:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
332Q8LF80    313   CKB21_ARATH Cyclin-dependent kinase B2-1 OS=A...3159e-40     149     29     49GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:TAIR.::GO:0016572; P:histone phosphorylation; IDA:TAIR.::GO:0009755; P:hormone-mediated signaling pathway; IEP:TAIR.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:TAIR.::GO:0009934; P:regulation of meristem structural organization; IMP:TAIR.
333Q63454    274   MK04_RAT Mitogen-activated protein kinase 4 O...2969e-40     148     36     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
334Q66HE7    352   CDKL1_RAT Cyclin-dependent kinase-like 1 OS=R...3239e-40     150     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007507; P:heart development; IEP:RGD.
335Q6ZAG3    324   CDKC3_ORYSJ Cyclin-dependent kinase C-3 OS=Or...3171e-39     149     33     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
336P34556    332   CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caeno...3171e-39     149     34     50GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:WormBase.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IMP:UniProtKB.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0001556; P:oocyte maturation; IMP:WormBase.::GO:0045836; P:positive regulation of meiosis; IMP:WormBase.::GO:0051446; P:positive regulation of meiotic cell cycle; IMP:UniProtKB.::GO:0035046; P:pronuclear migration; IMP:WormBase.
337Q95YH0    380   CDK8_DICDI Probable cyclin-dependent kinase 8...3411e-39     150     32     49GO:0005829; C:cytosol; IDA:dictyBase.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0016538; F:cyclin-dependent protein kinase regulator activity; ISS:dictyBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043689; P:cell-cell adhesion involved in flocculation; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:dictyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
338Q8SQU8    328   YBC9_ENCCU Probable cell division protein kin...3471e-39     149     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
339P23293    657   BUR1_YEAST Serine/threonine-protein kinase BU...3461e-39     153     32     49GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005634; C:nucleus; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:SGD.
GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IDA:SGD.
340P54665    345   CC2H2_TRYBB Cell division control protein 2 h...3181e-39     149     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
341Q8CEQ0    352   CDKL1_MOUSE Cyclin-dependent kinase-like 1 OS...3091e-39     149     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
342P49841    420   GSK3B_HUMAN Glycogen synthase kinase-3 beta O...3552e-39     150     31     48GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IDA:MGI.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IC:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0001837; P:epithelial to mesenchymal transition; IMP:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IDA:BHF-UCL.::GO:0021766; P:hippocampus development; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.::GO:0031333; P:negative regulation of protein complex assembly; IMP:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IC:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0032855; P:positive regulation of Rac GTPase activity; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0071109; P:superior temporal gyrus development; IMP:BHF-UCL.
343Q03957    528   CTK1_YEAST CTD kinase subunit alpha OS=Saccha...3492e-39     152     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005654; C:nucleoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:SGD.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:SGD.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IDA:SGD.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0045903; P:positive regulation of translational fidelity; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
344Q9WV60    420   GSK3B_MOUSE Glycogen synthase kinase-3 beta O...3552e-39     150     31     48GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:MGI.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0007409; P:axonogenesis; IGI:MGI.::GO:0044337; P:canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0008283; P:cell proliferation; TAS:MGI.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0045444; P:fat cell differentiation; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0007520; P:myoblast fusion; IDA:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0032092; P:positive regulation of protein binding; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:MGI.::GO:0035372; P:protein localization to microtubule; IGI:MGI.::GO:0000320; P:re-entry into mitotic cell cycle; IDA:MGI.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IDA:UniProtKB.
345Q80YP0    303   CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus m...3032e-39     147     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
346Q6CCB0    405   SSN3_YARLI Serine/threonine-protein kinase SS...3362e-39     150     30     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
347P97377    346   CDK2_MOUSE Cyclin-dependent kinase 2 OS=Mus m...3562e-39     149     29     46GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0000781; C:chromosome, telomeric region; IDA:MGI.::GO:0000793; C:condensed chromosome; IDA:MGI.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0000805; C:X chromosome; IDA:MGI.::GO:0000806; C:Y chromosome; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:MGI.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032298; P:positive regulation of DNA-dependent DNA replication initiation; IGI:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:MGI.::GO:0006813; P:potassium ion transport; IGI:MGI.
348Q4KM47    358   CDK10_RAT Cyclin-dependent kinase 10 OS=Rattu...3082e-39     149     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
349Q09437    719   YP62_CAEEL Putative serine/threonine-protein ...3313e-39     152     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.
350Q3UTQ8    938   CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS...3263e-39     154     31     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
351Q9NYV4    1490   CDK12_HUMAN Cyclin-dependent kinase 12 OS=Hom...3213e-39     155     32     51GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IMP:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.::GO:0043405; P:regulation of MAP kinase activity; IMP:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
352P18266    420   GSK3B_RAT Glycogen synthase kinase-3 beta OS=...3553e-39     149     31     48GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0048156; F:tau protein binding; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IDA:RGD.
GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; IDA:RGD.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0050774; P:negative regulation of dendrite morphogenesis; IMP:RGD.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:RGD.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.
353Q55C57    473   GLKA_DICDI Probable serine/threonine-protein ...3054e-39     150     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005977; P:glycogen metabolic process; ISS:dictyBase.
354Q69ZA1    1511   CDK13_MOUSE Cyclin-dependent kinase 13 OS=Mus...3224e-39     154     31     50GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.
355E1BB52    1512   CDK13_BOVIN Cyclin-dependent kinase 13 OS=Bos...3224e-39     154     31     50GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.
356Q00534    326   CDK6_HUMAN Cyclin-dependent kinase 6 OS=Homo ...3155e-39     147     32     52GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0001726; C:ruffle; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0030332; F:cyclin binding; IPI:BHF-UCL.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL.
GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0007050; P:cell cycle arrest; TAS:UniProtKB.::GO:0043697; P:cell dedifferentiation; IMP:BHF-UCL.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021542; P:dentate gyrus development; ISS:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IEP:BHF-UCL.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0048699; P:generation of neurons; ISS:UniProtKB.::GO:0021670; P:lateral ventricle development; ISS:UniProtKB.::GO:2000773; P:negative regulation of cellular senescence; IDA:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IDA:BHF-UCL.::GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; IMP:BHF-UCL.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0003323; P:type B pancreatic cell development; IDA:UniProtKB.
357P18265    483   GSK3A_RAT Glycogen synthase kinase-3 alpha OS...3635e-39     150     30     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
358D2H526    1491   CDK12_AILME Cyclin-dependent kinase 12 OS=Ail...3175e-39     154     32     51GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
359O76039    1030   CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS...3266e-39     153     31     50GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0044294; C:dendritic growth cone; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HGNC.
GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:BHF-UCL.
GO:0001764; P:neuron migration; ISS:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:BHF-UCL.::GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.
360Q3MJK5    1484   CDK12_RAT Cyclin-dependent kinase 12 OS=Rattu...3216e-39     154     32     50GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IMP:UniProtKB.
361Q9U2Q9    362   GSK3_CAEEL Glycogen synthase kinase-3 OS=Caen...3616e-39     147     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0010467; P:gene expression; IMP:WormBase.::GO:0007281; P:germ cell development; IGI:WormBase.::GO:0035188; P:hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
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