Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR054W
Length:
388
Number of sequences:
5887
Description:
YPR054W SMK1 SGDID:S000006258, Chr XVI from 666280-667446, Genome Release 64-1-1, Verified ORF, "Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P40417    426   ERKA_DROME Mitogen-activated protein kinase E...3771e-73     241     39     58GO:0030054; C:cell junction; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:FlyBase.::GO:0019901; F:protein kinase binding; IPI:FlyBase.::GO:0008134; F:transcription factor binding; IPI:FlyBase.
GO:0034334; P:adherens junction maintenance; IMP:FlyBase.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0006916; P:anti-apoptosis; NAS:FlyBase.::GO:0048149; P:behavioral response to ethanol; IMP:FlyBase.::GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0007369; P:gastrulation; NAS:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:FlyBase.::GO:0046534; P:positive regulation of photoreceptor cell differentiation; IMP:FlyBase.::GO:0045467; P:R7 cell development; TAS:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; TAS:FlyBase.::GO:0050804; P:regulation of synaptic transmission; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase.
32Q39024    376   MPK4_ARATH Mitogen-activated protein kinase 4...3752e-73     239     35     58GO:0005829; C:cytosol; IDA:TAIR.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0006972; P:hyperosmotic response; IMP:TAIR.::GO:0042539; P:hypotonic salinity response; IDA:TAIR.::GO:0009868; P:jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway; TAS:TAIR.::GO:0007112; P:male meiosis cytokinesis; IMP:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0009409; P:response to cold; IDA:TAIR.::GO:0009620; P:response to fungus; IMP:TAIR.::GO:0009862; P:systemic acquired resistance, salicylic acid mediated signaling pathway; IMP:TAIR.
33P27638    372   SPK1_SCHPO Mitogen-activated protein kinase s...3267e-73     238     41     60GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IGI:PomBase.
GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; IMP:PomBase.
34Q52PH6    355   HOG1_ALTBR Mitogen-activated protein kinase H...3271e-72     237     42     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35Q702W0    400   HOG1_BLAAD Mitogen-activated protein kinase h...3431e-72     238     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
36Q5Z859    369   MPK4_ORYSJ Mitogen-activated protein kinase 4...3503e-72     236     38     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
37Q6Z437    370   MPK3_ORYSJ Mitogen-activated protein kinase 3...3503e-72     236     38     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
38O61443    365   MK14B_DROME Mitogen-activated protein kinase ...3624e-72     236     37     57GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; NAS:FlyBase.
GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IDA:UniProtKB.::GO:0006955; P:immune response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:FlyBase.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0030510; P:regulation of BMP signaling pathway; IDA:UniProtKB.::GO:0045088; P:regulation of innate immune response; IDA:UniProtKB.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0009651; P:response to salt stress; IMP:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase.
39Q4W6D3    355   HOG1_COCHE Mitogen-activated protein kinase H...3276e-72     235     42     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40Q9M1Z5    393   MPK10_ARATH Mitogen-activated protein kinase ...3508e-72     236     36     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
41Q40517    372   NTF3_TOBAC Mitogen-activated protein kinase h...3521e-71     235     38     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
42Q0U4L8    355   HOG1_PHANO Mitogen-activated protein kinase H...3271e-71     234     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43Q2WFL5    354   HOG1_COCMI Mitogen-activated protein kinase H...3272e-71     233     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44P16892    353   FUS3_YEAST Mitogen-activated protein kinase F...3472e-71     233     38     60GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007050; P:cell cycle arrest; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0043409; P:negative regulation of MAPK cascade; IPI:SGD.::GO:0010526; P:negative regulation of transposition, RNA-mediated; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IDA:SGD.
45Q9N272    365   MK13_PANTR Mitogen-activated protein kinase 1...3383e-71     234     39     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q3T0N5    366   MK13_BOVIN Mitogen-activated protein kinase 1...3493e-71     234     39     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47O02812    360   MK14_CANFA Mitogen-activated protein kinase 1...3683e-71     233     37     58GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48P0CP66    366   CPK1_CRYNJ Mitogen-activated protein kinase C...3504e-71     233     38     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
49P0CP67    366   CPK1_CRYNB Mitogen-activated protein kinase C...3504e-71     233     38     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
50A2QN07    396   MPKC_ASPNC Mitogen-activated protein kinase m...3434e-71     234     39     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
51Q9LQQ9    363   MPK13_ARATH Mitogen-activated protein kinase ...3454e-71     233     38     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
52O15264    365   MK13_HUMAN Mitogen-activated protein kinase 1...3504e-71     233     39     57GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
53Q00859    355   MAPK_FUSSO Mitogen-activated protein kinase O...3481e-70     232     38     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
54P70618    360   MK14_RAT Mitogen-activated protein kinase 14 ...3681e-70     232     36     58GO:0044445; C:cytosolic part; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IDA:RGD.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0051403; P:stress-activated MAPK cascade; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q9Z1B7    366   MK13_MOUSE Mitogen-activated protein kinase 1...3491e-70     232     38     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56Q2U469    344   MPKC_ASPOR Mitogen-activated protein kinase m...3221e-70     231     42     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
57Q40884    384   MAPK_PETHY Mitogen-activated protein kinase h...3521e-70     233     38     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
58Q9WTY9    366   MK13_RAT Mitogen-activated protein kinase 13 ...3491e-70     232     37     56GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59O23236    361   MPK14_ARATH Mitogen-activated protein kinase ...3111e-70     232     42     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
60Q16539    360   MK14_HUMAN Mitogen-activated protein kinase 1...3682e-70     231     36     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0051525; F:NFAT protein binding; ISS:BHF-UCL.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006928; P:cellular component movement; TAS:ProtInc.::GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.::GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030316; P:osteoclast differentiation; ISS:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0042770; P:signal transduction in response to DNA damage; IMP:BHF-UCL.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0090400; P:stress-induced premature senescence; IMP:BHF-UCL.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
61Q39025    376   MPK5_ARATH Mitogen-activated protein kinase 5...3432e-70     232     38     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
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