UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPR048W

Length:

623

Number of sequences:

5887

Description:

YPR048W TAH18 SGDID:S000006252, Chr XVI from 659182-661053, Genome Release 64-1-1, Verified ORF, "Conserved NAPDH-dependent diflavin reductase, component of an early step in the cytosolic Fe-S protein assembly (CIA) machinery; transfers electrons from NADPH to the Fe-S cluster of Dre2p; plays a pro-death role under oxidative stress"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	Q8T8C0	1209	NOS_BOMMO Nitric oxide synthase OS=Bombyx mor...	704	5e-24	111	23	40
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004517; F:nitric-oxide synthase activity; IEA:EC.
									GO:0006809; P:nitric oxide biosynthetic process; IEA:InterPro.
122	Q9Y8G7	1066	C505_FUSOX Bifunctional P-450:NADPH-P450 redu...	644	2e-22	106	24	41	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0003958; F:NADPH-hemoprotein reductase activity; IEA:EC.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
123	P36587	678	NCPR_SCHPO NADPH--cytochrome P450 reductase O...	688	3e-22	105	24	41	GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0003958; F:NADPH-hemoprotein reductase activity; TAS:PomBase.
									GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.
124	Q8K9D3	602	CYSJ_BUCAP Sulfite reductase [NADPH] flavopro...	631	1e-21	102	23	45
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
125	Q9US28	583	YKA1_SCHPO Uncharacterized FAD-binding protei...	414	4e-20	98.2	24	43	GO:0005739; C:mitochondrion; IDA:PomBase.
									GO:0030586; F:[methionine synthase reductase activity; ISS:PomBase.
									GO:0009086; P:methionine biosynthetic process; ISS:PomBase.]
126	P16603	691	NCPR_YEAST NADPH--cytochrome P450 reductase O...	715	5e-19	94.7	23	40	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IDA:SGD.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0003958; F:NADPH-hemoprotein reductase activity; IEA:EC.
									GO:0006696; P:ergosterol biosynthetic process; IMP:SGD.
127	Q09878	1006	MET10_SCHPO Probable sulfite reductase [NADPH...	417	3e-18	93.2	24	46	GO:0005829; C:cytosol; IDA:PomBase.::GO:0009337; C:sulfite reductase complex (NADPH); ISS:PomBase.
									GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; ISS:PomBase.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; ISS:PomBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
128	Q09744	571	YB63_SCHPO Uncharacterized FAD-binding protei...	350	6e-16	84.7	25	42	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0030586; F:[methionine synthase reductase activity; ISS:PomBase.
									GO:0009086; P:methionine biosynthetic process; ISS:PomBase.]
129	O61309	1153	NOS_LYMST Nitric oxide synthase OS=Lymnaea st...	541	8e-16	85.1	24	42
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004517; F:nitric-oxide synthase activity; IEA:EC.
									GO:0006809; P:nitric oxide biosynthetic process; IEA:InterPro.
130	P39692	1035	MET10_YEAST Sulfite reductase [NADPH] flavopr...	413	0.000000000000003	83.2	23	46	GO:0009337; C:sulfite reductase complex (NADPH); IDA:SGD.
									GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IMP:SGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
131	O32214	605	CYSJ_BACSU Sulfite reductase [NADPH] flavopro...	138	0.0000000000003	76.3	33	51
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
132	Q65T53	597	CYSJ_MANSM Sulfite reductase [NADPH] flavopro...	135	0.00000000002	70.5	32	52
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
133	Q6LM58	605	CYSJ_PHOPR Sulfite reductase [NADPH] flavopro...	138	0.00000000002	70.5	32	50
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
134	Q9JUD8	604	CYSJ_NEIMA Sulfite reductase [NADPH] flavopro...	132	0.0000000004	66.2	33	47
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
135	A9LZ73	604	CYSJ_NEIM0 Sulfite reductase [NADPH] flavopro...	132	0.0000000004	66.2	33	47
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
136	Q4JIJ2	695	MTRR_BOVIN Methionine synthase reductase OS=B...	139	0.0000000009	65.5	30	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030586; F:[methionine synthase reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.]
137	Q8ZBN6	606	CYSJ_YERPE Sulfite reductase [NADPH] flavopro...	133	0.000000002	64.7	32	46
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
138	Q1C3Z0	606	CYSJ_YERPA Sulfite reductase [NADPH] flavopro...	133	0.000000002	64.7	32	46
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
139	Q55318	413	FENR_SYNY3 Ferredoxin--NADP reductase OS=Syne...	243	0.00000004	59.3	27	46	GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
									GO:0004324; F:ferredoxin-NADP+ reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.
140	Q8C1A3	696	MTRR_MOUSE Methionine synthase reductase OS=M...	139	0.0000002	58.2	28	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030586; F:[methionine synthase reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.]
141	Q9UBK8	725	MTRR_HUMAN Methionine synthase reductase OS=H...	139	0.0000003	57.4	27	47	GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0030586; F:[methionine synthase reductase activity; TAS:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.::GO:0010181; F:FMN binding; TAS:UniProtKB.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; TAS:UniProtKB.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.]
142	Q498R1	700	MTRR_RAT Methionine synthase reductase OS=Rat...	139	0.0000004	57	27	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030586; F:[methionine synthase reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.]
143	Q2UHA7	695	NCPR_ASPOR NADPH--cytochrome P450 reductase O...	150	0.0000007	56.2	29	47	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0003958; F:NADPH-hemoprotein reductase activity; IEA:EC.
									GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
144	Q7VQH2	610	CYSJ_BLOFL Sulfite reductase [NADPH] flavopro...	135	0.000007	52.8	31	44
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
145	Q92037	164	NOS2_CARAU Nitric oxide synthase, inducible O...	109	0.000007	50.1	31	50
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004517; F:nitric-oxide synthase activity; IEA:EC.
									GO:0006809; P:nitric oxide biosynthetic process; IEA:InterPro.::GO:0018119; P:peptidyl-cysteine S-nitrosylation; ISS:UniProtKB.
146	O04397	375	FENR2_TOBAC Ferredoxin--NADP reductase, root-...	153	0.00002	50.8	24	46	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0042651; C:thylakoid membrane; IEA:InterPro.
									GO:0004324; F:ferredoxin-NADP+ reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
147	Q00598	363	FENR_CYAPA Ferredoxin--NADP reductase, cyanel...	230	0.00002	50.4	23	44	GO:0034060; C:cyanelle stroma; IEA:UniProtKB-SubCell.::GO:0033115; C:cyanelle thylakoid membrane; IEA:UniProtKB-SubCell.
									GO:0004324; F:ferredoxin-NADP+ reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
148	P52674	522	CYSJ_THIRO Sulfite reductase [NADPH] flavopro...	133	0.00003	50.8	28	50
									GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
149	O34737	158	FLAV_BACSU Probable flavodoxin-1 OS=Bacillus ...	109	0.00003	48.1	31	42
									GO:0010181; F:FMN binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
150	Q8ETH0	406	HMP_OCEIH Flavohemoprotein OS=HTE831). GN=hmp...	171	0.00004	49.7	25	48
									GO:0071949; F:FAD binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008941; F:nitric oxide dioxygenase activity; IEA:EC.::GO:0019825; F:oxygen binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
									GO:0051409; P:response to nitrosative stress; IEA:InterPro.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.
151	P47169	1442	MET5_YEAST Sulfite reductase [NADPH] subunit ...	173	0.0001	49.3	28	43	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0009337; C:sulfite reductase complex (NADPH); IDA:SGD.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
									GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0000103; P:sulfate assimilation; IMP:SGD.

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