Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR041W
Length:
405
Number of sequences:
5887
Description:
YPR041W TIF5 SGDID:S000006245, Chr XVI from 648704-649921, Genome Release 64-1-1, Verified ORF, "Translation initiation factor eIF5; functions both as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP and as a GDP dissociation inhibitor to prevent recycling of eIF2"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38431    405   IF5_YEAST Eukaryotic translation initiation f...4050     833     100     100GO:0022627; C:cytosolic small ribosomal subunit; IPI:SGD.::GO:0043614; C:multi-eIF complex; IDA:SGD.
GO:0005092; F:GDP-dissociation inhibitor activity; IDA:SGD.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IPI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0042256; P:mature ribosome assembly; IMP:SGD.::GO:0045947; P:negative regulation of translational initiation; IMP:SGD.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
2Q09689    395   IF5_SCHPO Probable eukaryotic translation ini...4091e-104     322     44     60GO:0005829; C:cytosol; IDA:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; ISS:PomBase.::GO:0003743; F:translation initiation factor activity; ISS:PomBase.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0042256; P:mature ribosome assembly; ISS:PomBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
3Q9VXK6    464   IF5_DROME Eukaryotic translation initiation f...4183e-76     250     36     58
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
4P55010    431   IF5_HUMAN Eukaryotic translation initiation f...4131e-71     237     37     54GO:0005829; C:cytosol; NAS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.
GO:0006446; P:regulation of translational initiation; TAS:ProtInc.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
5P59325    429   IF5_MOUSE Eukaryotic translation initiation f...4313e-66     223     34     50
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
6Q22918    436   IF5_CAEEL Eukaryotic translation initiation f...4007e-65     219     36     54GO:0005851; C:eukaryotic translation initiation factor 2B complex; NAS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
7P48724    443   IF5_PHAVU Eukaryotic translation initiation f...4415e-54     191     34     48
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
8Q5R4L0    431   IF5_PONAB Eukaryotic translation initiation f...1482e-53     189     59     72
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
9Q07205    429   IF5_RAT Eukaryotic translation initiation fac...1482e-53     189     59     72
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IDA:RGD.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
10P55876    451   IF5_MAIZE Eukaryotic translation initiation f...4543e-51     184     33     47
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
11Q9S825    437   IF5Z_ARATH Probable eukaryotic translation in...4302e-48     176     32     47GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
12Q54LA1    393   IF5_DICDI Eukaryotic translation initiation f...4032e-45     166     31     49GO:0005829; C:cytosol; ISS:dictyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
13Q26891    162   IF5_TRICA Eukaryotic translation initiation f...1571e-22     97.4     38     55
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
14Q8TWR5    138   IF2B_METKA Translation initiation factor 2 su...1110.00000000000002     73.9     35     59
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
15A2SSW2    204   IF2B_METLZ Translation initiation factor 2 su...1200.000000000002     69.3     33     56
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
16Q2NHD9    142   IF2B_METST Translation initiation factor 2 su...1160.000000000004     67.4     32     55
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
17A7I5J0    204   IF2B_METB6 Translation initiation factor 2 su...1200.00000000008     64.7     31     56
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
18P56329    321   IF2B_SCHPO Probable eukaryotic translation in...1130.00000000009     66.2     34     59GO:0005829; C:cytosol; IDA:PomBase.::GO:0005850; C:eukaryotic translation initiation factor 2 complex; ISS:PomBase.::GO:0043614; C:multi-eIF complex; ISS:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003743; F:translation initiation factor activity; ISS:PomBase.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.
19Q8PWV1    202   IF2B_METMA Translation initiation factor 2 su...1290.0000000003     63.2     30     54
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
20O27958    137   IF2B_ARCFU Translation initiation factor 2 su...1160.0000000003     62     30     54
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
21O58312    140   IF2B_PYRHO Translation initiation factor 2 su...1170.0000000003     62     30     55
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
22A5UKI8    135   IF2B_METS3 Translation initiation factor 2 su...1160.0000000003     62     28     55
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
23A3CXJ3    205   IF2B_METMJ Translation initiation factor 2 su...1230.0000000004     62.4     30     54
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
24Q8TU91    202   IF2B_METAC Translation initiation factor 2 su...1300.0000000005     62.4     29     55
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
25C5A2A8    142   IF2B_THEGJ Translation initiation factor 2 su...1160.0000000007     61.2     28     55
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
26Q5JIT0    142   IF2B_PYRKO Translation initiation factor 2 su...1170.0000000007     61.2     28     55
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
27Q74M98    139   IF2B_NANEQ Translation initiation factor 2 su...1130.0000000007     60.8     35     50
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
28Q9UYR6    140   IF2B_PYRAB Translation initiation factor 2 su...1170.0000000007     60.8     29     55
GO:0003743; F:translation initiation factor activity; IEA:HAMAP.
29O27797    135   IF2B_METTH Translation initiation factor 2 su...1160.000000001     60.5     28     57
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
30Q8U3I5    140   IF2B_PYRFU Translation initiation factor 2 su...1160.000000001     60.5     30     55
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
31Q41969    268   IF2B_ARATH Eukaryotic translation initiation ...1310.000000004     60.8     32     51GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
records
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