Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR019W
Length:
933
Number of sequences:
5887
Description:
YPR019W MCM4 SGDID:S000006223, Chr XVI from 596750-599551, Genome Release 64-1-1, Verified ORF, "Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P30666    879   MCM3_SCHPO DNA replication licensing factor m...6917e-99     336     34     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0042555; C:MCM complex; IDA:PomBase.::GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0005656; C:pre-replicative complex; IC:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:PomBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IDA:PomBase.::GO:0000084; P:S phase of mitotic cell cycle; IC:PomBase.
32Q7Q0Q1    814   MCM6_ANOGA DNA replication licensing factor M...6667e-99     334     35     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
33P29496    775   MCM5_YEAST Minichromosome maintenance protein...7659e-99     333     30     50GO:0005737; C:cytoplasm; IDA:SGD.::GO:0031261; C:DNA replication preinitiation complex; IPI:SGD.::GO:0042555; C:MCM complex; IDA:SGD.::GO:0000784; C:nuclear chromosome, telomeric region; IDA:SGD.::GO:0005656; C:pre-replicative complex; IDA:SGD.::GO:0031298; C:replication fork protection complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0032508; P:DNA duplex unwinding; IDA:GOC.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0000727; P:double-strand break repair via break-induced replication; IMP:SGD.::GO:0006343; P:establishment of chromatin silencing; IMP:SGD.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IMP:SGD.::GO:0006267; P:pre-replicative complex assembly; IDA:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0000084; P:S phase of mitotic cell cycle; IMP:SGD.
34Q21902    759   MCM5_CAEEL DNA replication licensing factor m...7053e-98     331     33     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.
35Q9FL33    776   MCM3_ARATH DNA replication licensing factor M...5854e-98     331     35     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006268; P:DNA unwinding involved in replication; TAS:TAIR.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
36P40377    830   MCM2_SCHPO DNA replication licensing factor m...6415e-98     332     34     53GO:0031390; C:Ctf18 RFC-like complex; IC:PomBase.::GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0042555; C:MCM complex; IDA:PomBase.::GO:0005656; C:pre-replicative complex; IC:PomBase.::GO:0005657; C:replication fork; NAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:PomBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IDA:PomBase.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:PomBase.
37Q28CM3    821   MCM6M_XENTR Maternal DNA replication licensin...5508e-98     332     36     56GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006200; P:ATP catabolic process; ISS:GOC.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006268; P:DNA unwinding involved in replication; ISS:UniProtKB.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; ISS:UniProtKB.
38Q9V461    817   MCM6_DROME DNA replication licensing factor M...6239e-98     331     36     54GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0007307; P:eggshell chorion gene amplification; IMP:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
39Q0V8B7    734   MCM5_BOVIN DNA replication licensing factor M...6973e-97     328     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
40Q7ZY18    825   MC6ZB_XENLA Zygotic DNA replication licensing...5955e-97     330     34     55GO:0042555; C:MCM complex; IPI:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IC:UniProtKB.
41Q6P1V8    823   MCM6Z_XENTR Zygotic DNA replication licensing...5955e-97     329     34     55GO:0042555; C:MCM complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
42Q5FWY4    821   MCM6M_XENLA Maternal DNA replication licensin...5506e-97     329     36     56GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0042555; C:MCM complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006200; P:ATP catabolic process; IDA:GOC.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006268; P:DNA unwinding involved in replication; IDA:UniProtKB.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IDA:UniProtKB.
43Q29JI9    815   MCM6_DROPS DNA replication licensing factor M...6258e-97     328     36     53GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
44Q43704    768   MCM31_MAIZE DNA replication licensing factor ...5821e-96     327     35     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
45P49718    733   MCM5_MOUSE DNA replication licensing factor M...6971e-96     326     32     52GO:0042555; C:MCM complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
46Q9SX03    768   MCM33_MAIZE DNA replication licensing factor ...6992e-96     326     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
47Q9SX04    768   MCM32_MAIZE DNA replication licensing factor ...5823e-96     326     34     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
48P49731    892   MCM6_SCHPO DNA replication licensing factor m...7054e-96     329     34     51GO:0031390; C:Ctf18 RFC-like complex; IC:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0042555; C:MCM complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IDA:PomBase.::GO:0005656; C:pre-replicative complex; IC:PomBase.::GO:0005657; C:replication fork; NAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:PomBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IDA:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0000084; P:S phase of mitotic cell cycle; IC:PomBase.
49Q498J7    823   MC6ZA_XENLA Zygotic DNA replication licensing...5992e-95     325     34     54GO:0042555; C:MCM complex; IPI:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IC:UniProtKB.
50P33992    734   MCM5_HUMAN DNA replication licensing factor M...6982e-95     323     32     52GO:0042555; C:MCM complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
51P97311    821   MCM6_MOUSE DNA replication licensing factor M...5984e-93     319     34     54GO:0042555; C:MCM complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IPI:MGI.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006268; P:DNA unwinding involved in replication; IPI:MGI.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
52Q14566    821   MCM6_HUMAN DNA replication licensing factor M...5911e-92     318     35     54GO:0042555; C:MCM complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.
GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
53P29469    868   MCM2_YEAST DNA replication licensing factor M...6801e-92     318     31     50GO:0005737; C:cytoplasm; IDA:SGD.::GO:0031261; C:DNA replication preinitiation complex; IDA:SGD.::GO:0042555; C:MCM complex; IDA:SGD.::GO:0005656; C:pre-replicative complex; IDA:SGD.::GO:0031298; C:replication fork protection complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032508; P:DNA duplex unwinding; IDA:GOC.::GO:0006271; P:DNA strand elongation involved in DNA replication; IMP:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0000727; P:double-strand break repair via break-induced replication; IMP:SGD.::GO:0006267; P:pre-replicative complex assembly; IDA:SGD.::GO:0000084; P:S phase of mitotic cell cycle; IMP:SGD.
54Q2KIZ8    821   MCM6_BOVIN DNA replication licensing factor M...5912e-92     317     35     54GO:0042555; C:MCM complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
55P49739    807   MCM3M_XENLA Maternal DNA replication licensin...5672e-91     313     34     51GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0042555; C:MCM complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006200; P:ATP catabolic process; IDA:GOC.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006268; P:DNA unwinding involved in replication; IDA:UniProtKB.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IDA:UniProtKB.
56Q9XYU0    720   MCM7_DROME DNA replication licensing factor M...5341e-89     307     39     55GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.
57Q86B14    867   MCM6_DICDI DNA replication licensing factor m...5731e-89     310     34     52GO:0042555; C:MCM complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
58P34647    810   MCM6_CAEEL DNA replication licensing factor m...6679e-88     303     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.
59Q61J08    810   MCM6_CAEBR DNA replication licensing factor m...5603e-86     300     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
60Q5ZMN2    812   MCM3_CHICK DNA replication licensing factor M...5026e-85     296     36     54GO:0042555; C:MCM complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
61P25206    812   MCM3_MOUSE DNA replication licensing factor M...6734e-84     293     32     51GO:0042555; C:MCM complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
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