Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL268W
Length:
869
Number of sequences:
5887
Description:
YPL268W PLC1 SGDID:S000006189, Chr XVI from 35236-37845, Genome Release 64-1-1, Verified ORF, "Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32383    869   PLC1_YEAST 1-phosphatidylinositol 4,5-bisphos...8690     1807     100     100GO:0000775; C:chromosome, centromeric region; IDA:SGD.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0032958; P:inositol phosphate biosynthetic process; IMP:SGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IDA:SGD.::GO:0034501; P:protein localization to kinetochore; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IGI:SGD.
2O13433    1099   PLC1_CANAX 1-phosphatidylinositol 4,5-bisphos...8062e-117     389     36     52
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
3P40977    899   PLC1_SCHPO 1-phosphatidylinositol 4,5-bisphos...7835e-117     384     34     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0044242; P:cellular lipid catabolic process; IC:PomBase.::GO:0034644; P:cellular response to UV; IMP:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0019220; P:regulation of phosphate metabolic process; ISS:PomBase.
4A5D6R3    784   PLD3A_DANRE 1-phosphatidylinositol 4,5-bispho...6582e-77     273     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
5Q32NH8    758   PLCD4_XENLA 1-phosphatidylinositol 4,5-bispho...7986e-72     257     29     44GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
6Q4R6L3    799   PLCD4_MACFA 1-phosphatidylinositol 4,5-bispho...6878e-72     258     31     46GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
7Q5RET0    762   PLCD4_PONAB 1-phosphatidylinositol 4,5-bispho...6594e-71     255     31     47GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
8Q9BRC7    762   PLCD4_HUMAN 1-phosphatidylinositol 4,5-bispho...6595e-71     254     31     47GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
9Q8K2J0    785   PLCD3_MOUSE 1-phosphatidylinositol 4,5-bispho...6815e-71     255     29     46GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0001525; P:angiogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060716; P:labyrinthine layer blood vessel development; IGI:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IGI:MGI.
10P21671    791   PLCD4_BOVIN 1-phosphatidylinositol 4,5-bispho...8129e-71     254     28     44GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
11Q8N3E9    789   PLCD3_HUMAN 1-phosphatidylinositol 4,5-bispho...6791e-66     243     29     45GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
12P10688    756   PLCD1_RAT 1-phosphatidylinositol 4,5-bisphosp...8214e-66     240     28     45GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0005509; F:calcium ion binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:RGD.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0051482; P:elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0032962; P:positive regulation of inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0010701; P:positive regulation of norepinephrine secretion; IMP:RGD.::GO:0010044; P:response to aluminum ion; IEP:RGD.::GO:0051592; P:response to calcium ion; IMP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IMP:RGD.::GO:0034696; P:response to prostaglandin F stimulus; IEP:RGD.
13P10895    756   PLCD1_BOVIN 1-phosphatidylinositol 4,5-bispho...8134e-65     238     27     45
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
14Q62711    772   PLCD4_RAT 1-phosphatidylinositol 4,5-bisphosp...8054e-65     238     28     46GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; TAS:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
15Q8R3B1    756   PLCD1_MOUSE 1-phosphatidylinositol 4,5-bispho...8142e-62     229     27     45GO:0005829; C:cytosol; IDA:MGI.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0001525; P:angiogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060716; P:labyrinthine layer blood vessel development; IGI:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IGI:MGI.
16Q8K4D7    647   PLCZ1_MOUSE 1-phosphatidylinositol 4,5-bispho...6818e-62     226     28     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0006816; P:calcium ion transport; IDA:MGI.::GO:0007343; P:egg activation; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
17Q5FX52    645   PLCZ1_RAT 1-phosphatidylinositol 4,5-bisphosp...6502e-61     224     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
18Q1RML2    634   PLCZ1_BOVIN 1-phosphatidylinositol 4,5-bispho...6546e-60     220     29     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
19Q7YRU3    636   PLCZ1_PIG 1-phosphatidylinositol 4,5-bisphosp...6632e-59     219     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
20Q9UPR0    1127   PLCL2_HUMAN Inactive phospholipase C-like pro...6062e-59     223     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro.
21P51178    756   PLCD1_HUMAN 1-phosphatidylinositol 4,5-bispho...8106e-59     219     27     45GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0032794; F:GTPase activating protein binding; IPI:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.
22Q8K394    1128   PLCL2_MOUSE Inactive phospholipase C-like pro...6068e-59     222     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro.
23Q02158    801   PLC_DICDI 1-phosphatidylinositol 4,5-bisphosp...7398e-55     207     26     45
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IMP:dictyBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:dictyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0050922; P:negative regulation of chemotaxis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; TAS:dictyBase.
24Q2VRL0    637   PLCZ1_CHICK 1-phosphatidylinositol 4,5-bispho...6491e-54     204     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
25Q15111    1095   PLCL1_HUMAN Inactive phospholipase C-like pro...5281e-51     200     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0006629; P:lipid metabolic process; IEA:InterPro.
26P10894    1216   PLCB1_BOVIN 1-phosphatidylinositol 4,5-bispho...6193e-51     198     30     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
27Q9NQ66    1216   PLCB1_HUMAN 1-phosphatidylinositol 4,5-bispho...6194e-51     198     30     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0000790; C:nuclear chromatin; ISS:BHF-UCL.::GO:0016607; C:nuclear speck; IDA:BHF-UCL.
GO:0005516; F:calmodulin binding; IPI:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; NAS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0060466; P:activation of meiosis involved in egg activation; ISS:BHF-UCL.::GO:0021987; P:cerebral cortex development; ISS:BHF-UCL.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; ISS:BHF-UCL.::GO:0051318; P:G1 phase; ISS:BHF-UCL.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:BHF-UCL.::GO:0007215; P:glutamate receptor signaling pathway; ISS:BHF-UCL.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:BHF-UCL.::GO:0070498; P:interleukin-1-mediated signaling pathway; IDA:BHF-UCL.::GO:0035722; P:interleukin-12-mediated signaling pathway; IDA:BHF-UCL.::GO:0035723; P:interleukin-15-mediated signaling pathway; IDA:BHF-UCL.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007613; P:memory; ISS:BHF-UCL.::GO:2000438; P:negative regulation of monocyte extravasation; ISS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0046488; P:phosphatidylinositol metabolic process; ISS:BHF-UCL.::GO:2000344; P:positive regulation of acrosome reaction; ISS:BHF-UCL.::GO:2000560; P:positive regulation of CD24 biosynthetic process; ISS:BHF-UCL.::GO:0048639; P:positive regulation of developmental growth; ISS:BHF-UCL.::GO:0040019; P:positive regulation of embryonic development; ISS:BHF-UCL.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0045663; P:positive regulation of myoblast differentiation; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0080154; P:regulation of fertilization; ISS:BHF-UCL.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:BHF-UCL.::GO:0007268; P:synaptic transmission; TAS:Reactome.
28Q3USB7    1096   PLCL1_MOUSE Inactive phospholipase C-like pro...5284e-51     198     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0050811; F:GABA receptor binding; TAS:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007610; P:behavior; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro.
29Q9QW07    1175   PLCB4_RAT 1-phosphatidylinositol 4,5-bisphosp...6565e-51     198     29     45GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0043267; P:negative regulation of potassium ion transport; IMP:RGD.::GO:0007602; P:phototransduction; NAS:RGD.
30Q15147    1175   PLCB4_HUMAN 1-phosphatidylinositol 4,5-bispho...6585e-51     198     28     44GO:0005829; C:cytosol; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
31Q9Z1B3    1216   PLCB1_MOUSE 1-phosphatidylinositol 4,5-bispho...6195e-51     198     29     47GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0016607; C:nuclear speck; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005516; F:calmodulin binding; ISS:BHF-UCL.::GO:0019899; F:enzyme binding; ISS:BHF-UCL.::GO:0005521; F:lamin binding; IPI:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0060466; P:activation of meiosis involved in egg activation; IDA:BHF-UCL.::GO:0007155; P:cell adhesion; IC:BHF-UCL.::GO:0021987; P:cerebral cortex development; IMP:BHF-UCL.::GO:0030218; P:erythrocyte differentiation; TAS:BHF-UCL.::GO:0045444; P:fat cell differentiation; IDA:BHF-UCL.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; IMP:BHF-UCL.::GO:0051318; P:G1 phase; IDA:BHF-UCL.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0007215; P:glutamate receptor signaling pathway; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; TAS:BHF-UCL.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0035722; P:interleukin-12-mediated signaling pathway; ISS:BHF-UCL.::GO:0035723; P:interleukin-15-mediated signaling pathway; ISS:BHF-UCL.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0030225; P:macrophage differentiation; NAS:BHF-UCL.::GO:0007613; P:memory; IMP:BHF-UCL.::GO:0006397; P:mRNA processing; TAS:BHF-UCL.::GO:2000438; P:negative regulation of monocyte extravasation; IDA:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0001556; P:oocyte maturation; NAS:BHF-UCL.::GO:0046488; P:phosphatidylinositol metabolic process; ISS:BHF-UCL.::GO:2000344; P:positive regulation of acrosome reaction; IMP:BHF-UCL.::GO:2000560; P:positive regulation of CD24 biosynthetic process; IDA:BHF-UCL.::GO:0048639; P:positive regulation of developmental growth; IMP:BHF-UCL.::GO:0040019; P:positive regulation of embryonic development; IMP:BHF-UCL.::GO:0032735; P:positive regulation of interleukin-12 production; IMP:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; ISS:BHF-UCL.::GO:0045663; P:positive regulation of myoblast differentiation; IDA:BHF-UCL.::GO:0032417; P:positive regulation of sodium:hydrogen antiporter activity; NAS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0080154; P:regulation of fertilization; IMP:BHF-UCL.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IMP:BHF-UCL.
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