Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL268W
Length:
869
Number of sequences:
5887
Description:
YPL268W PLC1 SGDID:S000006189, Chr XVI from 35236-37845, Genome Release 64-1-1, Verified ORF, "Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P08487    1291   PLCG1_BOVIN 1-phosphatidylinositol 4,5-bispho...2624e-18     93.6     27     42GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; ISS:AgBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.
62O75038    1416   PLCH2_HUMAN 1-phosphatidylinositol 4,5-bispho...2755e-18     93.2     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
63Q8CIH5    1265   PLCG2_MOUSE 1-phosphatidylinositol 4,5-bispho...2896e-18     93.2     25     46GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0032237; P:activation of store-operated calcium channel activity; IMP:MGI.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0002316; P:follicular B cell differentiation; IMP:MGI.::GO:0032959; P:inositol trisphosphate biosynthetic process; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043069; P:negative regulation of programmed cell death; IMP:MGI.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
64P24135    1265   PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosp...2899e-18     92.4     25     45GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0033198; P:response to ATP; IDA:RGD.::GO:0032026; P:response to magnesium ion; IDA:RGD.
65P16885    1265   PLCG2_HUMAN 1-phosphatidylinositol 4,5-bispho...2701e-17     92     26     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; TAS:UniProtKB.
66Q01970    1234   PLCB3_HUMAN 1-phosphatidylinositol 4,5-bispho...2828e-17     89.4     26     44GO:0005829; C:cytosol; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IPI:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.
67Q07722    1023   PLCB4_BOVIN 1-phosphatidylinositol 4,5-bispho...2812e-16     87.8     28     44
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
68Q6NMA7    531   PLCD9_ARATH Phosphoinositide phospholipase C ...5370.00000000000003     80.1     22     38GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
69Q9STZ3    531   PLCD8_ARATH Phosphoinositide phospholipase C ...4800.00000000000004     79.7     22     38GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
70Q8BH74    926   NU107_MOUSE Nuclear pore complex protein Nup1...1200.44     38.1     28     46GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0031080; C:Nup107-160 complex; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
71Q12S23    251   UBIE_SHEDO Ubiquinone/menaquinone biosynthesi...1250.49     37     26     44
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-KW.::GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
72P57740    925   NU107_HUMAN Nuclear pore complex protein Nup1...1203.2     35     26     46GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031080; C:Nup107-160 complex; IDA:UniProtKB.
GO:0005487; F:nucleocytoplasmic transporter activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
73Q9CZX0    547   ELP3_MOUSE Elongator complex protein 3 OS=Mus...994.9     34.3     24     43GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
74Q8CDU5    853   EFHB_MOUSE EF-hand domain-containing family m...615.8     34.3     26     56
GO:0005509; F:calcium ion binding; IEA:InterPro.
75C0LGW2    884   PAM74_ARATH Probable LRR receptor-like serine...916.7     34.3     31     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
records
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