UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPL214C

Length:

540

Number of sequences:

5887

Description:

YPL214C THI6 SGDID:S000006135, Chr XVI from 150191-148569, Genome Release 64-1-1, reverse complement, Verified ORF, "Bifunctional enzyme with thiamine-phosphate pyrophosphorylase and 4-methyl-5-beta-hydroxyethylthiazole kinase activities, required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
631	B5E327	267	THIM2_STRP4 Hydroxyethylthiazole kinase 2 OS=...	162	0.000000008	60.5	31	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
632	B2INA6	268	THIM2_STRPS Hydroxyethylthiazole kinase 2 OS=...	300	0.00000001	60.1	26	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
633	Q9ZBL5	235	THIE_MYCLE Thiamine-phosphate synthase OS=Myc...	147	0.00000001	59.3	29	48
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
634	B8ZU95	235	THIE_MYCLB Thiamine-phosphate synthase OS=Myc...	147	0.00000001	59.3	29	48
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
635	O34294	204	THIE_RHIEC Thiamine-phosphate synthase OS=Rhi...	219	0.00000001	58.9	30	42
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
636	C4XIJ3	266	THIM_DESMR Hydroxyethylthiazole kinase OS=Des...	282	0.00000001	59.7	28	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
637	A4F727	223	THIE_SACEN Thiamine-phosphate synthase OS=Sac...	186	0.00000001	58.9	32	52
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
638	Q02YS4	250	THIM_LACLS Hydroxyethylthiazole kinase OS=Lac...	279	0.00000003	58.5	25	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
639	Q7WF72	217	THIE_BORBR Thiamine-phosphate synthase OS=(Al...	188	0.00000003	57.8	27	45
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
640	Q7W049	217	THIE_BORPE Thiamine-phosphate synthase OS=Bor...	188	0.00000005	57	27	45
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
641	Q7W3U2	217	THIE_BORPA Thiamine-phosphate synthase OS=Bor...	188	0.00000005	57	27	45
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
642	A1T2Z5	221	THIE_MYCVP Thiamine-phosphate synthase OS=Myc...	233	0.0000001	56.2	30	47
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
643	Q03XM8	273	THIM2_LEUMM Hydroxyethylthiazole kinase 2 OS=...	165	0.0000001	57	33	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
644	Q4FN35	207	THIE_PELUB Thiamine-phosphate synthase OS=Pel...	124	0.000003	51.6	30	50
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
645	Q8UAS9	246	THIM_AGRT5 Probable hydroxyethylthiazole kina...	293	0.00001	50.8	23	39
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
646	Q9CG46	250	THIM_LACLA Hydroxyethylthiazole kinase OS=lac...	277	0.00002	50.1	22	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
647	Q2T5T2	260	THIM_BURTA Hydroxyethylthiazole kinase OS=CIP...	194	0.001	44.3	27	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
648	A0PRY2	220	THIE_MYCUA Thiamine-phosphate synthase OS=Myc...	147	0.003	43.1	31	44
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
649	Q63L73	276	THIM_BURPS Hydroxyethylthiazole kinase OS=Bur...	195	0.004	42.7	27	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
650	A3NJS6	276	THIM_BURP6 Hydroxyethylthiazole kinase OS=Bur...	195	0.004	42.7	27	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
651	A3P5E2	276	THIM_BURP0 Hydroxyethylthiazole kinase OS=Bur...	195	0.004	42.7	27	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
652	B2HPZ9	220	THIE_MYCMM Thiamine-phosphate synthase OS=Myc...	147	0.007	41.6	30	44
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:EC.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
653	Q3JME7	276	THIM_BURP1 Hydroxyethylthiazole kinase OS=Bur...	195	0.014	41.2	26	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
654	P25053	205	TENI_BACSU Regulatory protein tenI OS=Bacillu...	228	0.21	37	23	44
									GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
655	Q73368	1435	POL_HV1B9 Gag-Pol polyprotein OS=(HIV-1). GN=...	81	1.9	35	37	51	GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004533; F:exoribonuclease H activity; IEA:EC.::GO:0004523; F:ribonuclease H activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0015074; P:DNA integration; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.::GO:0046797; P:viral procapsid maturation; IEA:UniProtKB-KW.
656	P18802	1432	POL_HV1ND Gag-Pol polyprotein OS=(HIV-1). GN=...	100	1.9	35	33	47	GO:0005829; C:cytosol; TAS:Reactome.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004533; F:exoribonuclease H activity; IEA:EC.::GO:0004523; F:ribonuclease H activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030260; P:entry into host cell; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019047; P:provirus integration; TAS:Reactome.::GO:0006278; P:RNA-dependent DNA replication; TAS:Reactome.::GO:0019061; P:uncoating of virus; TAS:Reactome.::GO:0046797; P:viral procapsid maturation; IEA:UniProtKB-KW.
657	P03367	1447	POL_HV1BR Gag-Pol polyprotein OS=BRU/LAI) (HI...	81	2	35	37	51	GO:0005829; C:cytosol; TAS:Reactome.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004533; F:exoribonuclease H activity; IEA:EC.::GO:0004523; F:ribonuclease H activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030260; P:entry into host cell; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019047; P:provirus integration; TAS:Reactome.::GO:0006278; P:RNA-dependent DNA replication; TAS:Reactome.::GO:0019061; P:uncoating of virus; TAS:Reactome.::GO:0046797; P:viral procapsid maturation; IEA:UniProtKB-KW.
658	P0C6F2	1435	POL_HV1LW Gag-Pol polyprotein OS=(HIV-1). GN=...	81	2	35	37	51	GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004533; F:exoribonuclease H activity; IEA:EC.::GO:0004523; F:ribonuclease H activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0015074; P:DNA integration; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.::GO:0046797; P:viral procapsid maturation; IEA:UniProtKB-KW.
659	P03366	1447	POL_HV1B1 Gag-Pol polyprotein OS=(HIV-1). GN=...	81	2	35	37	51	GO:0005829; C:cytosol; TAS:Reactome.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004533; F:exoribonuclease H activity; IEA:EC.::GO:0004523; F:ribonuclease H activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030260; P:entry into host cell; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019047; P:provirus integration; TAS:Reactome.::GO:0006278; P:RNA-dependent DNA replication; TAS:Reactome.::GO:0019061; P:uncoating of virus; TAS:Reactome.::GO:0046797; P:viral procapsid maturation; IEA:UniProtKB-KW.
660	P04587	1447	POL_HV1B5 Gag-Pol polyprotein OS=(HIV-1). GN=...	81	2.1	35	37	51	GO:0005829; C:cytosol; TAS:Reactome.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004533; F:exoribonuclease H activity; IEA:EC.::GO:0004523; F:ribonuclease H activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030260; P:entry into host cell; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019047; P:provirus integration; TAS:Reactome.::GO:0006278; P:RNA-dependent DNA replication; TAS:Reactome.::GO:0019061; P:uncoating of virus; TAS:Reactome.::GO:0046797; P:viral procapsid maturation; IEA:UniProtKB-KW.
661	P05961	1441	POL_HV1MN Gag-Pol polyprotein OS=(HIV-1). GN=...	81	2.3	35	37	51	GO:0005829; C:cytosol; TAS:Reactome.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
									GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004533; F:exoribonuclease H activity; IEA:EC.::GO:0004523; F:ribonuclease H activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030260; P:entry into host cell; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019047; P:provirus integration; TAS:Reactome.::GO:0006278; P:RNA-dependent DNA replication; TAS:Reactome.::GO:0019061; P:uncoating of virus; TAS:Reactome.::GO:0046797; P:viral procapsid maturation; IEA:UniProtKB-KW.

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