Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL177C
Length:
306
Number of sequences:
5887
Description:
YPL177C CUP9 SGDID:S000006098, Chr XVI from 213962-213042, Genome Release 64-1-1, reverse complement, Verified ORF, "Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P41817    306   CUP9_YEAST Homeobox protein CUP9 OS=Saccharom...3060     632     100     100GO:0005634; C:nucleus; IC:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:SGD.::GO:0001133; F:sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity; IC:SGD.
GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.
2P53147    276   TOS8_YEAST Homeobox protein TOS8 OS=Saccharom...704e-26     108     70     81GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
3Q96KN3    472   PKNX2_HUMAN Homeobox protein PKNOX2 OS=Homo s...760.0000000000001     74.7     41     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
4Q8BG99    474   PKNX2_MOUSE Homeobox protein PKNOX2 OS=Mus mu...760.0000000000001     74.3     41     66GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0015630; C:microtubule cytoskeleton; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0003785; F:actin monomer binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IGI:MGI.
5Q5R6L1    472   PKNX2_PONAB Homeobox protein PKNOX2 OS=Pongo ...760.0000000000002     73.9     39     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
6O46339    487   HTH_DROME Homeobox protein homothorax OS=Dros...620.0000000000002     73.6     47     66GO:0005667; C:transcription factor complex; IDA:UniProtKB.
GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IPI:FlyBase.
GO:0007420; P:brain development; IMP:FlyBase.::GO:0001752; P:compound eye photoreceptor fate commitment; IMP:FlyBase.::GO:0048735; P:haltere morphogenesis; IMP:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007479; P:leg disc proximal/distal pattern formation; TAS:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.::GO:0045664; P:regulation of neuron differentiation; IMP:FlyBase.::GO:0007432; P:salivary gland boundary specification; NAS:FlyBase.::GO:0010092; P:specification of organ identity; TAS:FlyBase.::GO:0007383; P:specification of segmental identity, antennal segment; IMP:FlyBase.
7P70284    272   TGIF1_MOUSE Homeobox protein TGIF1 OS=Mus mus...570.0000000000002     72     56     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IDA:MGI.::GO:0060041; P:retina development in camera-type eye; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8A8K0S8    358   ME3L2_HUMAN Putative homeobox protein Meis3-l...2030.0000000000003     72.8     30     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
9Q90655    269   AKR_CHICK Homeobox protein AKR OS=Gallus gall...570.0000000000003     71.6     56     70GO:0005634; C:nucleus; IC:Roslin.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q5IS58    401   TGIF1_PANTR Homeobox protein TGIF1 OS=Pan tro...570.0000000000008     71.6     56     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q15583    401   TGIF1_HUMAN Homeobox protein TGIF1 OS=Homo sa...1050.000000000001     71.6     39     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q2HJ84    436   PKNX1_BOVIN Homeobox protein PKNOX1 OS=Bos ta...830.000000000001     71.2     37     59
13Q9GZN2    237   TGIF2_HUMAN Homeobox protein TGIF2 OS=Homo sa...1140.000000000001     69.3     37     52GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14P55347    436   PKNX1_HUMAN Homeobox protein PKNOX1 OS=Homo s...830.000000000001     71.2     37     59
15O70477    436   PKNX1_MOUSE Homeobox protein PKNOX1 OS=Mus mu...830.000000000002     70.9     37     59GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
GO:0001525; P:angiogenesis; IMP:MGI.::GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0030218; P:erythrocyte differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI.
16Q6DIF3    453   MEIS3_XENTR Homeobox protein meis3 OS=Xenopus...570.000000000002     70.9     46     70GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q5U4X3    453   MEI3A_XENLA Homeobox protein meis3-A OS=Xenop...570.000000000002     70.9     46     70GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030902; P:hindbrain development; IMP:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q7ZY13    451   MEI3B_XENLA Homeobox protein meis3-B OS=Xenop...570.000000000002     70.9     46     70GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q8C0Y1    237   TGIF2_MOUSE Homeobox protein TGIF2 OS=Mus mus...570.000000000002     68.9     54     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0045666; P:positive regulation of neuron differentiation; IDA:MGI.::GO:0060041; P:retina development in camera-type eye; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20A6NDR6    274   ME3L1_HUMAN Putative homeobox protein Meis3-l...570.000000000003     68.9     46     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
21Q99687    375   MEIS3_HUMAN Homeobox protein Meis3 OS=Homo sa...680.000000000003     70.1     40     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
22P97368    378   MEIS3_MOUSE Homeobox protein Meis3 OS=Mus mus...630.000000000004     69.7     44     70GO:0005634; C:nucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI.
23P97367    477   MEIS2_MOUSE Homeobox protein Meis2 OS=Mus mus...560.000000000004     69.7     46     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0001654; P:eye development; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
24O14770    477   MEIS2_HUMAN Homeobox protein Meis2 OS=Homo sa...560.000000000004     69.7     46     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
25O00470    390   MEIS1_HUMAN Homeobox protein Meis1 OS=Homo sa...560.000000000009     68.6     46     68
26Q60954    390   MEIS1_MOUSE Homeobox protein Meis1 OS=Mus mus...560.000000000009     68.6     46     68GO:0005634; C:nucleus; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0001525; P:angiogenesis; IMP:MGI.::GO:0048514; P:blood vessel morphogenesis; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IMP:MGI.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0002089; P:lens morphogenesis in camera-type eye; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27P79937    390   MEIS1_XENLA Homeobox protein Meis1 OS=Xenopus...560.00000000001     68.6     46     68GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IGI:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0014036; P:neural crest cell fate specification; IGI:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q8SR09    192   HD2_ENCCU Homeobox protein HD-2 OS=Encephalit...540.00000000001     66.2     52     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
29Q8IUE1    241   TF2LX_HUMAN Homeobox protein TGIF2LX OS=Homo ...1000.00000000001     66.6     39     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q8MIB7    241   TF2LX_PANTR Homeobox protein TGIF2LX OS=Pan t...620.00000000001     66.6     48     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31A1YGI6    241   TF2LX_PANPA Homeobox protein TGIF2LX OS=Pan p...620.00000000001     66.6     48     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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