Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL176C
Length:
783
Number of sequences:
5887
Description:
YPL176C TRE1 SGDID:S000006097, Chr XVI from 218363-216012, Genome Release 64-1-1, reverse complement, Verified ORF, "Plasma membrane protein that binds to Bsd2p and regulates ubiquitylation and vacuolar degradation of the metal transporter Smf1p; function is redundant with that of Tre2p; has similarity to transferrin receptors"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q08919    783   TRE1_YEAST Uncharacterized protein TRE1 OS=Sa...7830     1622     100     100GO:0000324; C:fungal-type vacuole; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
2Q08693    809   TRE2_YEAST Putative zinc metalloprotease TRE2...7700     675     45     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
3O43023    794   YGV9_SCHPO Uncharacterized zinc metalloprotea...7941e-40     164     25     41GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0071627; C:integral to fungal-type vacuolar membrane; IC:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:PomBase.
4B2GUY2    798   TFR2_RAT Transferrin receptor protein 2 OS=Ra...4482e-22     106     25     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:InterPro.
5Q9JKX3    798   TFR2_MOUSE Transferrin receptor protein 2 OS=...4486e-22     105     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004998; F:transferrin receptor activity; TAS:MGI.
GO:0006879; P:cellular iron ion homeostasis; TAS:MGI.::GO:0006508; P:proteolysis; IEA:InterPro.
6Q9UP52    801   TFR2_HUMAN Transferrin receptor protein 2 OS=...3897e-22     105     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004998; F:transferrin receptor activity; NAS:UniProtKB.
GO:0006879; P:cellular iron ion homeostasis; TAS:UniProtKB.::GO:0006826; P:iron ion transport; NAS:UniProtKB.::GO:0006508; P:proteolysis; IEA:InterPro.
7Q62351    763   TFR1_MOUSE Transferrin receptor protein 1 OS=...4457e-20     98.6     24     44GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0070062; C:extracellular vesicular exosome; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0005381; F:iron ion transmembrane transporter activity; TAS:MGI.::GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004998; F:transferrin receptor activity; TAS:MGI.
GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0030316; P:osteoclast differentiation; IMP:DFLAT.::GO:0045780; P:positive regulation of bone resorption; IDA:DFLAT.::GO:0006508; P:proteolysis; IEA:InterPro.
8Q9CZR2    740   NALD2_MOUSE N-acetylated-alpha-linked acidic ...7229e-20     98.2     22     39GO:0016021; C:integral to membrane; IDA:MGI.
GO:0004180; F:carboxypeptidase activity; IDA:MGI.::GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0050129; F:N-formylglutamate deformylase activity; IDA:MGI.
GO:0042135; P:neurotransmitter catabolic process; IDA:MGI.::GO:0006508; P:proteolysis; IDA:MGI.
9P91406    770   GCP2_CAEEL Glutamate carboxypeptidase 2 homol...5632e-19     97.1     23     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004181; F:metallocarboxypeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; ISS:UniProtKB.
10Q9M1S8    705   GCP2_ARATH Probable glutamate carboxypeptidas...6243e-19     96.3     22     41GO:0016021; C:integral to membrane; NAS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004181; F:metallocarboxypeptidase activity; IMP:UniProtKB.
GO:0009790; P:embryo development; IMP:TAIR.::GO:0009908; P:flower development; IGI:TAIR.::GO:0010305; P:leaf vascular tissue pattern formation; IGI:TAIR.::GO:0009640; P:photomorphogenesis; IMP:TAIR.::GO:0006508; P:proteolysis; IMP:UniProtKB.::GO:0010080; P:regulation of floral meristem growth; IMP:UniProtKB.::GO:0010081; P:regulation of inflorescence meristem growth; IMP:UniProtKB.::GO:0010082; P:regulation of root meristem growth; IMP:UniProtKB.
11Q2V905    767   TFR1_HORSE Transferrin receptor protein 1 OS=...4502e-18     93.6     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
12Q9Y3Q0    740   NALD2_HUMAN N-acetylated-alpha-linked acidic ...5913e-18     93.2     23     42GO:0016021; C:integral to membrane; NAS:UniProtKB.
GO:0004180; F:carboxypeptidase activity; NAS:UniProtKB.::GO:0016805; F:dipeptidase activity; NAS:UniProtKB.::GO:0008239; F:dipeptidyl-peptidase activity; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB.
GO:0006508; P:proteolysis; NAS:UniProtKB.
13Q9UQQ1    740   NALDL_HUMAN N-acetylated-alpha-linked acidic ...5865e-18     92.4     22     40GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:UniProtKB.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14Q9MYZ3    769   TFR1_FELCA Transferrin receptor protein 1 OS=...4436e-18     92.4     22     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
15Q99376    622   TFR1_RAT Transferrin receptor protein 1 OS=Ra...4271e-17     90.9     22     43GO:0009986; C:cell surface; IDA:MGI.::GO:0070062; C:extracellular vesicular exosome; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0055038; C:recycling endosome membrane; IDA:RGD.
GO:0051087; F:chaperone binding; IPI:RGD.::GO:0030544; F:Hsp70 protein binding; IPI:RGD.::GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004998; F:transferrin receptor activity; IDA:RGD.
GO:0006953; P:acute-phase response; IEP:RGD.::GO:0007568; P:aging; IEP:RGD.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0046688; P:response to copper ion; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0010039; P:response to iron ion; IEP:RGD.::GO:0010042; P:response to manganese ion; IEP:RGD.::GO:0010033; P:response to organic substance; IEP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD.
16Q9GLD3    770   TFR1_CANFA Transferrin receptor protein 1 OS=...3293e-17     90.1     24     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
17Q07891    757   TFR1_CRIGR Transferrin receptor protein 1 OS=...3283e-17     89.7     25     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
18O54697    745   NALDL_RAT N-acetylated-alpha-linked acidic di...6034e-17     89.4     22     39GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
19Q8HZV3    768   TFR1_PIG Transferrin receptor protein 1 OS=Su...5028e-17     88.6     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
20P70627    752   FOLH1_RAT Glutamate carboxypeptidase 2 OS=Rat...4141e-16     88.2     23     44
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IDA:RGD.
21Q5WN23    770   GCP2_CAEBR Glutamate carboxypeptidase 2 homol...4091e-16     88.2     23     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004181; F:metallocarboxypeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; ISS:UniProtKB.
22Q04609    750   FOLH1_HUMAN Glutamate carboxypeptidase 2 OS=H...4195e-16     85.9     24     44GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; NAS:UniProtKB.
23Q7M758    745   NALDL_MOUSE N-acetylated-alpha-linked acidic ...6050.000000000000002     84     21     38GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
24O77564    751   FOLH1_PIG Glutamate carboxypeptidase 2 OS=Sus...4050.000000000000003     83.6     23     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
25Q5RDH6    760   TFR1_PONAB Transferrin receptor protein 1 OS=...3290.000000000000006     82.8     23     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
26P02786    760   TFR1_HUMAN Transferrin receptor protein 1 OS=...2540.000000000000008     82.4     26     45GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004998; F:transferrin receptor activity; NAS:UniProtKB.
GO:0006879; P:cellular iron ion homeostasis; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0033572; P:transferrin transport; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.
27Q90997    776   TFR1_CHICK Transferrin receptor protein 1 OS=...3790.00000000000002     81.3     25     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
28O35409    752   FOLH1_MOUSE Glutamate carboxypeptidase 2 OS=M...4130.00000000000003     80.5     22     43GO:0005887; C:integral to plasma membrane; IDA:MGI.
GO:0004180; F:carboxypeptidase activity; IDA:MGI.::GO:0016805; F:dipeptidase activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006760; P:folic acid-containing compound metabolic process; IDA:MGI.::GO:0006508; P:proteolysis; IDA:MGI.
29P47161    811   VPS70_YEAST Vacuolar protein sorting-associat...3420.0000000006     66.6     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
30Q9HBA9    442   FOH1B_HUMAN Putative N-acetylated-alpha-linke...1450.000002     54.7     22     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
31Q58DX5    795   NADL2_HUMAN Inactive N-acetylated-alpha-linke...2600.00002     52.4     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008233; F:peptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
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