Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL174C
Length:
868
Number of sequences:
5887
Description:
YPL174C NIP100 SGDID:S000006095, Chr XVI from 222773-220167, Genome Release 64-1-1, reverse complement, Verified ORF, "Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q8CI96    704   CLIP4_MOUSE CAP-Gly domain-containing linker ...420.00007     50.1     52     64
32Q5FVQ9    524   TBCE_RAT Tubulin-specific chaperone E OS=Ratt...950.001     46.2     33     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.
33Q8CIV8    524   TBCE_MOUSE Tubulin-specific chaperone E OS=Mu...920.001     46.2     36     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0051082; F:unfolded protein binding; TAS:MGI.
GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0000226; P:microtubule cytoskeleton organization; IMP:MGI.::GO:0014889; P:muscle atrophy; IMP:MGI.::GO:0048936; P:peripheral nervous system neuron axonogenesis; IMP:MGI.::GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0007021; P:tubulin complex assembly; TAS:MGI.
34P34531    937   YM92_CAEEL Uncharacterized protein M01A8.2 OS...620.001     46.2     34     55
35Q10235    234   ALP11_SCHPO Cell polarity protein alp11 OS=Sc...460.003     43.9     39     61GO:0005829; C:cytosol; IDA:PomBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0043014; F:alpha-tubulin binding; IPI:PomBase.
GO:0000226; P:microtubule cytoskeleton organization; IC:PomBase.::GO:0007023; P:post-chaperonin tubulin folding pathway; NAS:PomBase.
36Q15813    527   TBCE_HUMAN Tubulin-specific chaperone E OS=Ho...1460.004     44.7     29     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; TAS:ProtInc.
GO:0051087; F:chaperone binding; TAS:ProtInc.
GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.::GO:0007023; P:post-chaperonin tubulin folding pathway; IDA:UniProtKB.
37Q5U508    522   TBCE_XENLA Tubulin-specific chaperone E OS=Xe...810.006     43.9     32     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.
38Q21313    3672   EPI1_CAEEL Laminin-like protein epi-1 OS=Caen...2920.01     43.5     24     47GO:0005604; C:basement membrane; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:InterPro.
39Q5RBD9    527   TBCE_PONAB Tubulin-specific chaperone E OS=Po...1440.012     42.7     28     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.
40Q32KS0    528   TBCE_BOVIN Tubulin-specific chaperone E OS=Bo...550.024     42     40     47GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0007023; P:post-chaperonin tubulin folding pathway; TAS:Reactome.
41P11709    440   BIK1_YEAST Nuclear fusion protein BIK1 OS=Sac...560.031     41.6     32     57GO:0005938; C:cell cortex; IDA:SGD.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0035371; C:microtubule plus end; IDA:SGD.::GO:0005876; C:spindle microtubule; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.
GO:0008017; F:microtubule binding; IGI:SGD.::GO:0042803; F:protein homodimerization activity; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000742; P:karyogamy involved in conjugation with cellular fusion; IMP:SGD.::GO:0000092; P:mitotic anaphase B; TAS:SGD.::GO:0000022; P:mitotic spindle elongation; IGI:SGD.::GO:0030472; P:mitotic spindle organization in nucleus; TAS:SGD.::GO:0031115; P:negative regulation of microtubule polymerization; IDA:SGD.::GO:0000743; P:nuclear migration involved in conjugation with cellular fusion; IMP:SGD.
42Q55CN0    525   TBCE_DICDI Tubulin-specific chaperone E OS=Di...390.15     39.3     41     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
43Q80TQ2    952   CYLD_MOUSE Ubiquitin carboxyl-terminal hydrol...1170.36     38.1     32     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0006412; P:translation; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
44Q66H62    953   CYLD_RAT Ubiquitin carboxyl-terminal hydrolas...1170.38     38.1     32     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro.
GO:0003735; F:structural constituent of ribosome; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0006412; P:translation; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
45P79065    461   TIP1_SCHPO Tip elongation protein 1 OS=Schizo...630.47     37.7     35     49GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0051010; F:microtubule plus-end binding; TAS:PomBase.::GO:0046982; F:protein heterodimerization activity; IPI:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0034613; P:cellular protein localization; IMP:PomBase.::GO:0033554; P:cellular response to stress; NAS:PomBase.::GO:0030010; P:establishment of cell polarity; NAS:PomBase.::GO:0046785; P:microtubule polymerization; IGI:PomBase.::GO:0010570; P:regulation of filamentous growth; IMP:PomBase.
46Q5RED8    956   CYLD_PONAB Ubiquitin carboxyl-terminal hydrol...1170.62     37.4     32     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro.
GO:0003735; F:structural constituent of ribosome; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0006412; P:translation; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
47Q9NQC7    956   CYLD_HUMAN Ubiquitin carboxyl-terminal hydrol...1170.64     37.4     32     45GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro.
GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IDA:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IMP:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0006412; P:translation; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
48Q1RMU2    953   CYLD_BOVIN Ubiquitin carboxyl-terminal hydrol...951.1     36.6     33     46GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro.
GO:0003735; F:structural constituent of ribosome; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0006412; P:translation; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
49Q937H2    1479   MUKB_KLEPN Chromosome partition protein MukB ...2541.4     36.6     24     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
50Q62168    407   K1H2_MOUSE Keratin, type I cuticular Ha2 OS=M...3181.8     35.8     23     40GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
51Q54CS9    1351   RAD50_DICDI DNA repair protein RAD50 OS=Dicty...2472     35.8     21     51GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0030870; C:Mre11 complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:dictyBase.::GO:0003690; F:double-stranded DNA binding; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030674; F:protein binding, bridging; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:dictyBase.
GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0006303; P:double-strand break repair via nonhomologous end joining; ISS:dictyBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0000019; P:regulation of mitotic recombination; ISS:UniProtKB.::GO:0007004; P:telomere maintenance via telomerase; ISS:UniProtKB.
52Q15058    1648   KIF14_HUMAN Kinesin-like protein KIF14 OS=Hom...1053.5     35     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
53Q54IX3    2531   PKS26_DICDI Probable polyketide synthase 26 O...1403.6     35     23     44
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
54P24043    3122   LAMA2_HUMAN Laminin subunit alpha-2 OS=Homo s...2904.9     34.7     22     38GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; TAS:ProtInc.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
55P30427    4687   PLEC_RAT Plectin OS=Rattus norvegicus (Rat). ...1664.9     34.7     24     45GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0005200; F:structural constituent of cytoskeleton; IMP:RGD.
GO:0030855; P:epithelial cell differentiation; IEP:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB.::GO:0007584; P:response to nutrient; IDA:RGD.
56Q8K299    491   SCAR5_MOUSE Scavenger receptor class A member...1065     34.3     28     48GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.
GO:0070287; F:ferritin receptor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.
GO:0006879; P:cellular iron ion homeostasis; IDA:UniProtKB.::GO:0034605; P:cellular response to heat; IDA:MGI.::GO:0034755; P:iron ion transmembrane transport; IDA:UniProtKB.::GO:0070207; P:protein homotrimerization; IPI:UniProtKB.
57A6T716    1482   MUKB_KLEP7 Chromosome partition protein MukB ...2575.3     34.7     24     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
58O67610    248   FABG_AQUAE 3-oxoacyl-[acyl-carrier-protein] r...1077     33.5     31     49
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
59Q60675    3106   LAMA2_MOUSE Laminin subunit alpha-2 OS=Mus mu...2597.6     34.3     21     42GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
60Q6ZMJ2    495   SCAR5_HUMAN Scavenger receptor class A member...1578     33.9     23     43GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.
GO:0070287; F:ferritin receptor activity; ISS:UniProtKB.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.
GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0034755; P:iron ion transmembrane transport; ISS:UniProtKB.::GO:0070207; P:protein homotrimerization; ISS:UniProtKB.
61C5BAC7    1485   MUKB_EDWI9 Chromosome partition protein MukB ...1829.1     33.9     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
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