Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL174C
Length:
868
Number of sequences:
5887
Description:
YPL174C NIP100 SGDID:S000006095, Chr XVI from 222773-220167, Genome Release 64-1-1, reverse complement, Verified ORF, "Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P33420    868   NIP80_YEAST Protein NIP100 OS=Saccharomyces c...8680     1740     100     100GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005869; C:dynactin complex; IDA:SGD.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0003774; F:motor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000132; P:establishment of mitotic spindle orientation; IMP:SGD.
2Q01397    1367   DYNA_NEUCR Dynactin, 150 kDa isoform OS=1257 ...910.000000000007     73.2     43     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0003774; F:motor activity; IEA:UniProtKB-KW.
3P30622    1438   CLIP1_HUMAN CAP-Gly domain-containing linker ...1030.00000000001     72.4     41     51GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; TAS:ProtInc.::GO:0005882; C:intermediate filament; TAS:ProtInc.::GO:0000776; C:kinetochore; TAS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0031116; P:positive regulation of microtubule polymerization; IMP:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
4Q922J3    1391   CLIP1_MOUSE CAP-Gly domain-containing linker ...490.0000000001     69.3     59     73GO:0005881; C:cytoplasmic microtubule; IDA:MGI.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0035371; C:microtubule plus end; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008017; F:microtubule binding; IDA:MGI.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0031116; P:positive regulation of microtubule polymerization; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
5O42184    1433   CLIP1_CHICK CAP-Gly domain-containing linker ...490.0000000001     69.3     59     73GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006810; P:transport; IEA:UniProtKB-KW.
6Q9Z0H8    1047   CLIP2_MOUSE CAP-Gly domain-containing linker ...500.0000000003     67.8     54     74GO:0005881; C:cytoplasmic microtubule; IDA:MGI.
7Q9UDT6    1046   CLIP2_HUMAN CAP-Gly domain-containing linker ...500.0000000003     67.8     54     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005875; C:microtubule associated complex; TAS:ProtInc.
8O55156    1046   CLIP2_RAT CAP-Gly domain-containing linker pr...500.0000000006     67     54     74GO:0005881; C:cytoplasmic microtubule; IDA:UniProtKB.::GO:0030425; C:dendrite; TAS:UniProtKB.::GO:0042599; C:lamellar body; TAS:RGD.::GO:0005875; C:microtubule associated complex; IDA:RGD.
GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
GO:0007026; P:negative regulation of microtubule depolymerization; NAS:UniProtKB.
9Q5R686    547   CLIP3_PONAB CAP-Gly domain-containing linker ...590.000000001     65.5     49     66GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; ISS:UniProtKB.
GO:0035594; F:ganglioside binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.
GO:0072321; P:chaperone-mediated protein transport; ISS:UniProtKB.::GO:0045444; P:fat cell differentiation; ISS:UniProtKB.::GO:0044091; P:membrane biogenesis; ISS:UniProtKB.::GO:0031115; P:negative regulation of microtubule polymerization; ISS:UniProtKB.::GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0045807; P:positive regulation of endocytosis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0010828; P:positive regulation of glucose transport; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
10Q96DZ5    547   CLIP3_HUMAN CAP-Gly domain-containing linker ...590.000000001     65.5     49     66GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; IDA:UniProtKB.
GO:0035594; F:ganglioside binding; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.
GO:0072321; P:chaperone-mediated protein transport; IMP:UniProtKB.::GO:0045444; P:fat cell differentiation; ISS:UniProtKB.::GO:0044091; P:membrane biogenesis; IMP:UniProtKB.::GO:0031115; P:negative regulation of microtubule polymerization; IMP:UniProtKB.::GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045807; P:positive regulation of endocytosis; IMP:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0010828; P:positive regulation of glucose transport; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
11B9EHT4    547   CLIP3_MOUSE CAP-Gly domain-containing linker ...590.000000001     65.1     49     66GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; ISS:UniProtKB.
GO:0035594; F:ganglioside binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.
GO:0072321; P:chaperone-mediated protein transport; ISS:UniProtKB.::GO:0045444; P:fat cell differentiation; IEP:UniProtKB.::GO:0044091; P:membrane biogenesis; ISS:UniProtKB.::GO:0031115; P:negative regulation of microtubule polymerization; ISS:UniProtKB.::GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0045807; P:positive regulation of endocytosis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IDA:UniProtKB.::GO:0010828; P:positive regulation of glucose transport; IMP:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
12Q5U243    534   CLIP3_XENLA CAP-Gly domain-containing linker ...590.000000002     65.1     49     66GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
13Q5VT06    3117   CE350_HUMAN Centrosome-associated protein 350...680.000000004     64.7     44     60GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
14Q20728    229   TBCB_CAEEL Tubulin-specific chaperone B OS=Ca...440.000000004     61.2     52     77GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
15Q54Z01    270   TBCB_DICDI Tubulin-specific chaperone B OS=Di...710.000000004     62     41     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
16Q9VJE5    1690   CL190_DROME Restin homolog OS=Drosophila mela...640.000000005     63.9     42     58GO:0045169; C:fusome; IDA:FlyBase.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005875; C:microtubule associated complex; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:FlyBase.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.
GO:0007349; P:cellularization; IMP:UniProtKB.
17O42667    670   SSM4_SCHPO Microtubule-associated protein ssm...610.00000004     60.8     46     56GO:0030981; C:cortical microtubule cytoskeleton; IDA:PomBase.::GO:0005881; C:cytoplasmic microtubule; IDA:PomBase.::GO:0005869; C:dynactin complex; ISS:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0051010; F:microtubule plus-end binding; NAS:PomBase.
GO:0030437; P:ascospore formation; IGI:PomBase.::GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; IMP:PomBase.::GO:0034613; P:cellular protein localization; IMP:PomBase.::GO:0030989; P:dynein-driven meiotic oscillatory nuclear movement; IMP:PomBase.::GO:0000743; P:nuclear migration involved in conjugation with cellular fusion; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0007129; P:synapsis; IMP:PomBase.
18Q5E951    244   TBCB_BOVIN Tubulin-folding cofactor B OS=Bos ...580.00000006     58.2     48     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007023; P:post-chaperonin tubulin folding pathway; TAS:Reactome.
19Q99426    244   TBCB_HUMAN Tubulin-folding cofactor B OS=Homo...580.00000007     57.8     47     57GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
20Q9D1E6    244   TBCB_MOUSE Tubulin-folding cofactor B OS=Mus ...580.0000001     57     47     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
21Q66HD5    599   CLIP4_RAT CAP-Gly domain-containing linker pr...670.0000002     58.5     43     58
22O08788    1281   DCTN1_MOUSE Dynactin subunit 1 OS=Mus musculu...1090.0000003     58.2     30     50GO:0031252; C:cell leading edge; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0003774; F:motor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006810; P:transport; IEA:UniProtKB-KW.
23P28023    1280   DCTN1_RAT Dynactin subunit 1 OS=Rattus norveg...1080.0000004     57.8     30     52GO:0005868; C:cytoplasmic dynein complex; IDA:RGD.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0008017; F:microtubule binding; NAS:RGD.::GO:0003777; F:microtubule motor activity; TAS:RGD.
GO:0007017; P:microtubule-based process; TAS:RGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
24Q14203    1278   DCTN1_HUMAN Dynactin subunit 1 OS=Homo sapien...790.0000005     57.4     34     53GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0003774; F:motor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; NAS:ProtInc.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
25P13496    1265   DCTN1_DROME Dynactin subunit 1 OS=Drosophila ...410.000003     55.1     51     63GO:0005869; C:dynactin complex; TAS:FlyBase.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0000776; C:kinetochore; IDA:FlyBase.::GO:0005828; C:kinetochore microtubule; IDA:FlyBase.::GO:0031616; C:spindle pole centrosome; IDA:FlyBase.
GO:0045502; F:dynein binding; TAS:FlyBase.::GO:0003774; F:motor activity; IEA:UniProtKB-KW.
GO:0001709; P:cell fate determination; IMP:FlyBase.::GO:0051299; P:centrosome separation; IMP:FlyBase.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IDA:FlyBase.::GO:0006886; P:intracellular protein transport; IMP:FlyBase.::GO:0051383; P:kinetochore organization; IMP:FlyBase.::GO:0047497; P:mitochondrion transport along microtubule; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0051028; P:mRNA transport; IMP:FlyBase.::GO:0048477; P:oogenesis; NAS:FlyBase.::GO:0042052; P:rhabdomere development; IMP:FlyBase.::GO:0016330; P:second mitotic wave involved in compound eye morphogenesis; IMP:FlyBase.::GO:0051225; P:spindle assembly; IMP:FlyBase.
26Q9NQT8    1826   KI13B_HUMAN Kinesin-like protein KIF13B OS=Ho...620.000003     54.7     40     55GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007018; P:microtubule-based movement; TAS:UniProtKB.::GO:0006605; P:protein targeting; TAS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.::GO:0042110; P:T cell activation; NAS:UniProtKB.
27Q6PCJ1    1232   DCTN1_XENLA Dynactin subunit 1 OS=Xenopus lae...860.000005     54.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0003774; F:motor activity; IEA:UniProtKB-KW.
28Q8N3C7    705   CLIP4_HUMAN CAP-Gly domain-containing linker ...420.000007     53.5     57     67
29P35458    1224   DCTN1_CHICK Dynactin subunit 1 OS=Gallus gall...1300.000007     53.9     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0003774; F:motor activity; IEA:UniProtKB-KW.
30Q5U378    521   TBCE_DANRE Tubulin-specific chaperone E OS=Da...600.00001     52.4     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.
31Q8CI96    704   CLIP4_MOUSE CAP-Gly domain-containing linker ...420.00007     50.1     52     64
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