UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YPL157W

Length:

315

Number of sequences:

5887

Description:

YPL157W TGS1 SGDID:S000006078, Chr XVI from 254814-255761, Genome Release 64-1-1, Verified ORF, "Trimethyl guanosine synthase, conserved nucleolar methyl transferase that converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for nucleolar assembly and splicing of meiotic pre-mRNAs"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q12052	315	TGS1_YEAST Trimethylguanosine synthase OS=Sac...	315	0	660	100	100	GO:0005730; C:nucleolus; IDA:SGD.
									GO:0008173; F:RNA methyltransferase activity; IMP:SGD.
									GO:0007126; P:meiosis; IMP:SGD.::GO:0017126; P:nucleologenesis; IMP:SGD.::GO:0032210; P:regulation of telomere maintenance via telomerase; IMP:SGD.::GO:0006387; P:snRNA capping; IMP:SGD.
2	P85107	850	TGS1_RAT Trimethylguanosine synthase OS=Rattu...	214	6e-34	136	37	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009452; P:RNA capping; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3	Q96RS0	853	TGS1_HUMAN Trimethylguanosine synthase OS=Hom...	214	4e-33	134	36	54	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030532; C:small nuclear ribonucleoprotein complex; IC:BHF-UCL.
									GO:0071164; F:RNA trimethylguanosine synthase activity; IDA:BHF-UCL.
									GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0034660; P:ncRNA metabolic process; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0071167; P:ribonucleoprotein complex import into nucleus; IC:BHF-UCL.::GO:0009452; P:RNA capping; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4	Q923W1	853	TGS1_MOUSE Trimethylguanosine synthase OS=Mus...	181	6e-32	130	39	56	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009452; P:RNA capping; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5	Q09814	239	TGS1_SCHPO Trimethylguanosine synthase OS=Sch...	181	1e-26	109	38	51	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; ISS:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
									GO:0008990; F:rRNA (guanine-N2-)-methyltransferase activity; IMP:PomBase.
									GO:0006387; P:snRNA capping; IMP:PomBase.
6	Q7NJS7	286	PRMC_GLOVI Release factor glutamine methyltra...	214	0.0000002	55.5	23	40
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
7	Q7VXJ6	298	PRMB_BORPE 50S ribosomal protein L3 glutamine...	163	0.00001	49.7	25	44	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.::GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:InterPro.
8	A9WBM9	283	PRMC_CHLAA Release factor glutamine methyltra...	112	0.00003	48.1	29	42
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
9	Q99YP3	451	Y1606_STRP1 Uncharacterized RNA methyltransfe...	167	0.00005	48.5	23	43
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
10	A3MWC5	195	CBIT_PYRCJ Probable cobalt-precorrin-6Y C(15)...	64	0.00008	46.2	34	61
									GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
11	O26249	192	CBIT_METTH Probable cobalt-precorrin-6Y C(15)...	98	0.0001	45.8	33	49
									GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
12	Q5XAU1	451	Y1337_STRP6 Uncharacterized RNA methyltransfe...	166	0.0002	46.6	23	43
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
13	Q9UY84	329	TMG10_PYRAB tRNA (guanine(10)-N2)-dimethyltra...	146	0.0002	46.2	28	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004809; F:tRNA (guanine-N2-)-methyltransferase activity; IDA:UniProtKB.::GO:0000049; F:tRNA binding; IDA:UniProtKB.
14	O26820	336	TMG10_METTH tRNA (guanine(10)-N2)-dimethyltra...	104	0.0002	45.8	31	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
									GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
15	Q8P017	451	Y1615_STRP8 Uncharacterized RNA methyltransfe...	167	0.0003	45.8	22	43
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
16	P0DG17	451	Y1299_STRPQ Uncharacterized RNA methyltransfe...	167	0.0003	45.8	22	43
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
17	P0DG16	451	Y1299_STRP3 Uncharacterized RNA methyltransfe...	167	0.0003	45.8	22	43
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
18	Q89DG5	319	PRMB_BRAJA 50S ribosomal protein L3 glutamine...	82	0.0005	44.7	33	48	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.::GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:InterPro.
19	Q5E6T2	284	PRMC_VIBF1 Release factor glutamine methyltra...	85	0.001	43.9	29	52
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
20	A6UPM1	180	CBIT_METVS Probable cobalt-precorrin-6Y C(15)...	122	0.001	42.4	29	50
									GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
21	Q5UQR2	256	YL320_MIMIV Uncharacterized protein L320 OS=A...	127	0.002	42.7	28	43
									GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0009452; P:RNA capping; IEA:InterPro.::GO:0001510; P:RNA methylation; IEA:InterPro.
22	Q1RH40	556	RFTRM_RICBR Bifunctional methyltransferase OS...	83	0.003	43.1	27	48
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.::GO:0008176; F:tRNA (guanine-N7-)-methyltransferase activity; IEA:EC.
23	Q4UJU4	527	RFTRM_RICFE Bifunctional methyltransferase OS...	81	0.003	42.7	30	47
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.::GO:0008176; F:tRNA (guanine-N7-)-methyltransferase activity; IEA:EC.
24	Q9KF10	458	Y687_BACHD Uncharacterized RNA methyltransfer...	164	0.004	42	20	42
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
25	Q7NWP9	514	RLMD_CHRVO 23S rRNA (uracil(1939)-C(5))-methy...	107	0.004	42.4	26	46
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
26	Q9ZCB3	518	RFTRM_RICPR Bifunctional methyltransferase OS...	132	0.006	41.6	23	42
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.::GO:0008176; F:tRNA (guanine-N7-)-methyltransferase activity; IEA:EC.
27	Q97WC7	199	CBIT_SULSO Probable cobalt-precorrin-6Y C(15)...	91	0.008	40.4	29	52
									GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
28	Q9Y5R4	338	HEMK1_HUMAN HemK methyltransferase family mem...	84	0.009	40.8	31	42	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008170; F:N-methyltransferase activity; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
									GO:0006306; P:DNA methylation; IEA:InterPro.
29	A5UJR5	187	CBIT_METS3 Probable cobalt-precorrin-6Y C(15)...	58	0.01	40	34	55
									GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
30	Q92G13	524	RFTRM_RICCN Bifunctional methyltransferase OS...	97	0.01	41.2	28	43
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008276; F:protein methyltransferase activity; IEA:InterPro.::GO:0008176; F:tRNA (guanine-N7-)-methyltransferase activity; IEA:EC.
31	Q8ES75	459	Y768_OCEIH Uncharacterized RNA methyltransfer...	135	0.011	40.8	22	44
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.

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